Computational Systems Biology, 2/e : From Molecular Mechanisms to Disease (Hardcover)

This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling.

• Logical information flow aids understanding of basic building blocks of life through disease phenotypes
• Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns
• Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation
• Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.

這本經過全面修訂的第二版《計算系統生物學》討論了生物系統在分子、細胞或有機體層面上的實驗和理論基礎，涵蓋了時間和空間尺度，並且隨著系統生物學的發展，提供了解決複雜醫學問題的臨床解決方案。特別是該書聚焦於生物系統的工程和網絡建模。

- 邏輯信息流有助於通過疾病表型理解生命的基本構建塊
- 進化原則揭示了生物組織的基本組織原則和系統過程，控制著適應或響應模式等功能
- 技術工具和系統的涵蓋範圍幫助研究人員使用先進的計算方法來理解和解決特定的系統生物學問題
- 不同尺度上的多尺度建模有助於研究人員理解生物組織和功能的時空關係的相依性和限制。