Virus as Populations: Composition, Complexity, Quasispecies, Dynamics, and Biological Implications
暫譯: 病毒作為族群：組成、複雜性、準種、動態及生物學意涵

Domingo, Esteban

Virus as Populations: Composition, Complexity, Quasispecies, Dynamics, and Biological Implications
  • 出版商: Academic Press
  • 出版日期: 2019-11-15
  • 售價: $4,380
  • 貴賓價: 9.5 折 $4,161
  • 語言: 英文
  • 頁數: 424
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 0128163313
  • ISBN-13: 9780128163313

    • 海外代購書籍(需單獨結帳)

相關主題

商品描述

Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included.

The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere.

商品描述(中文翻譯)

《病毒作為組成、複雜性、準種群、動態及生物學意涵，第二版》解釋了圍繞病毒作為複雜群體在感染宿主中複製的基本概念。病毒行為中的基本現象，例如適應變化環境的能力、產生疾病的能力，以及被傳播或對治療反應的概率，均依賴於病毒群體的數量。書中包括了準種群動態、突變率、病毒適應性、瓶頸事件的影響、病毒傳播和疾病出現中的群體數量，以及新的抗病毒策略等概念。

本書的主要概念是基於最近從宏基因組研究中得出的病毒多樣性觀察，以及當前對病毒在生物圈演化中的起源和角色的看法。

目錄大綱

Introduction to Virus Origins and Their Role in Biological Evolution
2. Molecular Basis of Genetic Variation of Viruses
3. Darwinian Principles Acting on Highly Mutable Viruses
4. Dynamics of Virus Populations and Their Hosts
5. Viral Fitness as a Measure of Adaptation
6. Virus Population Dynamics Examined with Experimental Model Systems 
7. Long-term Virus Evolution in Nature
8. Quasispecies Dynamics in Disease Prevention and Control
9. Trends in Antiviral Strategies
10. Collective Population Effects in Non-Viral Systems

目錄大綱(中文翻譯)

Introduction to Virus Origins and Their Role in Biological Evolution

2. Molecular Basis of Genetic Variation of Viruses

3. Darwinian Principles Acting on Highly Mutable Viruses

4. Dynamics of Virus Populations and Their Hosts

5. Viral Fitness as a Measure of Adaptation

6. Virus Population Dynamics Examined with Experimental Model Systems 

7. Long-term Virus Evolution in Nature

8. Quasispecies Dynamics in Disease Prevention and Control

9. Trends in Antiviral Strategies

10. Collective Population Effects in Non-Viral Systems

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