Toward Replacement Parts for the Brain : Implantable Biomimetic Electronics as Neural Prostheses (Hardcover)

Theodore W. Berger, Dennis L. Glanzman

  • 出版商: A Bradford Book
  • 出版日期: 2005-06-24
  • 定價: $1,980
  • 售價: 5.0$990
  • 語言: 英文
  • 頁數: 480
  • 裝訂: Hardcover
  • ISBN: 0262025779
  • ISBN-13: 9780262025775

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Description:

The continuing development of implantable neural prostheses signals a new era in bioengineering and neuroscience research. This collection of essays outlines current advances in research on the intracranial implantation of devices that can communicate with the brain in order to restore sensory, motor, or cognitive functions. The contributors explore the creation of biologically realistic mathematical models of brain function, the production of microchips that incorporate those models, and the integration of microchip and brain function through neuron-silicon interfaces. Recent developments in understanding the computational and cognitive properties of the brain and rapid advances in biomedical and computer engineering both contribute to this cutting-edge research.

The book first examines the development of sensory system prostheses -- cochlear, retinal, and visual implants -- as the best foundation for considering the extension of neural prostheses to the central brain region. The book then turns to the complexity of neural representations, offering, among other approaches to the topic, one of the few existing theoretical frameworks for modeling the hierarchical organization of neural systems. Next, it examines the challenges of designing and controlling the interface between neurons and silicon, considering the necessity for bidirectional communication and for multiyear duration of the implant. Finally, the book looks at hardware implementations and explores possible ways to achieve the complexity of neural function in hardware, including the use of VLSI and photonic technologies.

Theodore W. Berger is Professor of Biomedical Engineering in the School of Engineering at the University of Southern California.

Dennis L. Glanzman is Program Chief for Theoretical and Computational Neuroscience at the National Institute of Mental Health (NIMH).

 

Table of Contents:

Preface vii
I SENSORY SYSTEMS 1
1 We Made the Deaf Hear. Now What?
Gerald E. Loeb
3
2 Microelectronic Array for Stimulation of Large Retinal Tissue Areas
Dean Scribner, M. Humayun, Brian Justus, Charles Merritt, R. Klein, J. G. Howard, M. Peckerar, F. K. Perkins, E. Margalit, Kah-Guan Au Eong, J. Weiland, E. de Juan, Jr., J. Finch, R. Graham, C. Trautfield and S. Taylor
15
3 Imaging Two-Dimensional Neural Activity Patterns in the Cat Visual Cortex using a Multielectrode Array
David J. Warren, Richard A. Normann and Alexei Koulakov
43
II NEURAL REPRESENTATIONS 67
4 Brain Parts on Multiple Scales: Examples from the Auditory System
Ellen Covey
69
5 A Protocol for Reading the Mind
Howard Eichenbaum
91
6 Cognitive Processes in Replacement Brain Parts: A Code for All Reasons
Robert Hampson, John Simeral and Sam A. Deadwyler
111
7 Mathematical Modeling as a Basic Tool for Neuromimetic Circuits
Gilbert A. Chauvet, P. Chauvet and Theodore W. Berger
129
8 Real-Time Spatiotemporal Databases to Support Human Motor Skills
Shahram Ghandeharizadeh
159
III NEURON/SILICON INTERFACES 175
9 Long-Term Functional Contact between Nerve Cell Networks and Microelectrode Arrays
Guenter W. Gross, Emese Dian, Edward G. Keefer, Alexandra Gramowski and Simone Stuewe
177
10 Building Minimalistic Hybrid Neuroelectric Devices
James J. Hickman
205
11 The Biotic/Abiotic Interface: Achievements and Foreseeable Challenges
Roberta Diaz Brinton, Walid Sousou, Michel Baudry, Mark Thompson and Theodore W. Berger
221
IV HARDWARE IMPLEMENTATIONS 239
12 Brain-Implantable Biomimetic Electronics as a Neural Prosthesis for Hippocampal Memory Function
Theodore W. Berger, Roberta Diaz Brinton, Vasilis Z. Marmarelis, Bing J. Sheu and Armand R. Tanguay, Jr.
241
13 Brain Circuit Implementation: High-Precision Computation from Low-Precision Components
Richard Granger
277
14 Hybrid Electronic/Photonic Multichip Modules for Vision and Neural Prosthetic Applications
Armand R. Tanguay, Jr. and B. Keith Jenkins
295
15 Reconfigurable Processors for Neural Prostheses
Jose Mumbru, Krishna V. Shenoy, George Panotopoulos, Suat Ay, Xin An, Fai Mok and Demetri Psaltis
335
16 The Coming Revolution: The Merging of Computational Neural Science and Semiconductor Engineering
Dan Hammerstorm
369
Contributors 385
Index 389