Every Living Creature: How Xenotransplantation Will Change Our Lives
暫譯: 每一個生物:異種移植將如何改變我們的生活
Mezrich, Joshua D.
- 出版商: Summit Valley Press
- 出版日期: 2026-04-07
- 售價: $1,330
- 貴賓價: 9.5 折 $1,264
- 語言: 英文
- 頁數: 264
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 0262051168
- ISBN-13: 9780262051163
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商品描述
The incredible history and promise of inter-species organ transplantation. With more than 100,000 patients in the United States waiting for life-saving organ transplants, the shortage of organs will never be solved if someone must die for someone else to be saved. And yet a solution is well within reach--xenotransplantation, or the transplanting of organs between different species--the once unimaginable scientific achievement that Joshua Mezrich explores in Every Living Creature. The story begins with efforts using chimpanzees and baboons in the 60s through the 90s, rife with ethical and practical complications and disappointments. The successful cloning of Dolly the sheep revived xeno-optimism, followed by the discovery of CRISPR-Cas9, which finally opened the door to xenotransplantation in humans, using genetically modified pigs as organ donors. The protagonists of this story are as incredible as the science it details: a transgender visionary, the highest paid female CEO in the world, who simply wants her daughter to live; the surgeon saved by a high-risk heart transplant, who swears by the promise of pigs' organs; the brilliant and brash surgeon-scientist-entrepreneur who is risking everything to make xenotransplantation a reality. Each plays a part in what is, in the end, the story of a miracle--not the answer to a prayer, as Every Living Creature makes clear, but a miracle we can breed.
商品描述(中文翻譯)
跨物種器官移植的驚人歷史與未來潛力。
在美國,有超過100,000名患者等待拯救生命的器官移植,如果必須有人死亡才能拯救他人,器官短缺的問題將永遠無法解決。然而,一個解決方案就在眼前——異種移植(xenotransplantation),即在不同物種之間進行器官移植——這一曾經難以想像的科學成就,正是喬舒亞·梅茲里奇(Joshua Mezrich)在每一個活著的生物中所探討的。 故事始於60年代至90年代使用黑猩猩和狒狒的努力,這些努力充滿了倫理和實際的複雜性以及失望。多莉羊的成功克隆重燃了對異種移植的樂觀,隨後CRISPR-Cas9的發現,最終為人類的異種移植打開了大門,使用基因改造的豬作為器官捐贈者。 這個故事的主角與其所詳述的科學一樣令人驚奇:一位跨性別的遠見者,世界上薪水最高的女性CEO,她只是希望她的女兒能活下去;一位因高風險心臟移植而獲救的外科醫生,他堅信豬的器官的潛力;一位聰明而大膽的外科醫生-科學家-企業家,他冒著一切風險使異種移植成為現實。每個人都在這個故事中扮演著角色,最終這是一個奇蹟的故事——正如每一個活著的生物所明確指出的,這不是一個祈禱的答案,而是一個我們可以培育的奇蹟。作者簡介
Joshua Mezrich is Professor of Surgery at the University of Wisconsin and holds the Mark A. Fischer Chair in Transplantation.
作者簡介(中文翻譯)
約書亞·梅茲里奇(Joshua Mezrich)是威斯康辛大學的外科教授,並擔任馬克·A·費舍爾(Mark A. Fischer)移植椅的職位。