Sinusoidal Cells in Liver Diseases: Role in Their Pathophysiology, Diagnosis, and Treatment

Gracia-Sancho, Jordi

  • 出版商: Academic Press
  • 出版日期: 2024-04-10
  • 售價: $5,750
  • 貴賓價: 9.5$5,463
  • 語言: 英文
  • 頁數: 562
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 0323952623
  • ISBN-13: 9780323952620
  • 海外代購書籍(需單獨結帳)

商品描述

Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics.

Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure.

商品描述(中文翻譯)

《肝臟疾病中的正弦細胞:其在病理生理學、診斷和治療中的角色》提供了對肝臟正弦細胞(LSECs、HSCs、巨噬細胞和其他非實質細胞)在急性和慢性肝臟疾病中角色的最新進展的綜述。該書強調疾病的病理生理學、新機制、未解決的臨床問題、生物標記物的發展和治療機會。通過關注正弦細胞在人類肝臟疾病中的角色,本書全面概述了正弦細胞在急性和慢性肝臟疾病中的角色、其病理生理學和機制,以及新生物標記物和新治療方法的發展。

肝臟血管細胞在急性和慢性肝臟疾病的病理生理學中起著重要作用,被認為是治療大多數人類肝病的關鍵治療靶點。本書涵蓋了肝臟血管細胞中發生的表型變化以及細胞如何促進微循環功能障礙、纖維化、發炎和肝功能衰竭的發展。