Biomedical Application of Nanoparticles

Biomedical Application of Nanoparticles explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system and targeted cells. Risk assessment of nanoparticles for human is described, including: cellular paradigms, transcriptomics and toxicogenomics. Finally, the applications of nanoparticles in medicine and antioxidant regenerative therapeutics are presented in several chapters with emphasis on how nanoparticles enhance transport of drugs across biological membrane barriers and therefore may enhance drug bioavailability.

Bertrand Henri Rihn, MD, DSc, professor of biochemistry and molecular biol-ogy at Lorraine University, France, is a leading expert in the field of particulate toxicology, with research topics including safety toxicology, immunotoxicology, and investigating the transcriptomic changes in macrophages following nanopar-ticle exposure. In addition to his research, Professor Rihn has also worked as a clinical toxicologist, and was awarded the Baratz Award (2004) and the E. Taub Award (2011) from the National Academy of Medicine (France). He also served as the president of the French Society of Toxicology from 2007 to 2009, and was a EUROTOX Registered Toxicologist.