Bioconductor Case Studies

Florian Hahne, Wolfgang Huber, Robert Gentleman, Seth Falcon

  • 出版商: Springer
  • 出版日期: 2008-08-15
  • 售價: $5,471
  • 貴賓價: 9.5$5,197
  • 語言: 英文
  • 頁數: 284
  • 裝訂: Paperback
  • ISBN: 0387772391
  • ISBN-13: 9780387772394

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商品描述

Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include

* import and preprocessing of data from various sources

* statistical modeling of differential gene expression

* biological metadata

* application of graphs and graph rendering

* machine learning for clustering and classification problems

* gene set enrichment analysis

Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table.