Exocytosis from Molecules to Cells

This book is divided into three sections: 1) Components of exocytotic pathways; 2) Biophysical insights from synthetic and reconstituted systems; and, 3) Physiological systems of exocytosis. The first section begins with a description of how secretory organelles form and are packaged with appropriate constituents for exocytosis. The second includes two chapters on recently published reconstituted systems of SNARE-mediated fusion. The final third of the book summarizes the cellular and molecular mechanisms of exocytosis and its regulation in diverse systems.

This book is a reference for researchers and students in the fields of exocytosis and membrane trafficking who hope to gain a broad understanding of how these processes operate in various cell types. Historical perspectives on exocytosis are also presented and discussed.

Key Features:

• Comprehensive and cohesive molecules-to-systems presentation of key features of secretory pathways.

• Presents a single volume description of exocytosis regulatory mechanisms in many different cell types.

• A number of chapter authors are highly regarded researchers in the field.

• Detailed descriptions are provided of diverse systems of exocytosis including yeast exocytosis and exosomal secretion.

• Incorporates methodologies that are routinely used by biophysicists to study exocytosis and membrane fusion including electrochemistry, electrophysiology, reconstitution assays, and high-resolution fluorescence imaging.

這本書分為三個部分：1) 胞外分泌途徑的組成部分；2) 來自合成和重構系統的生物物理洞察；以及3) 胞外分泌的生理系統。第一部分首先描述了分泌顆粒如何形成並與適當的成分一起打包進行胞外分泌。第二部分包括兩章關於最近發表的重構系統中SNARE介導的融合。該書的最後一部分總結了胞外分泌的細胞和分子機制以及其在不同系統中的調節。

這本書是胞外分泌和膜運輸領域的研究人員和學生的參考資料，他們希望對這些過程在各種細胞類型中的運作有一個廣泛的理解。書中還介紹和討論了胞外分泌的歷史觀點。

主要特點：
- 全面且連貫地介紹了分泌途徑的關鍵特點。
- 在許多不同的細胞類型中描述了胞外分泌的調節機制。
- 一些章節的作者是該領域中受到高度尊重的研究人員。
- 提供了對包括酵母胞外分泌和外泌體分泌在內的多種胞外分泌系統的詳細描述。
- 結合了生物物理學家常用的方法，如電化學、電生理學、重構試驗和高分辨率螢光成像，來研究胞外分泌和膜融合。

以上是對該段文字的翻譯。