Biotechnological Relevance of Cytochrome P450 in Boosting Agricultural Production and Food Security
暫譯: 細胞色素P450在提升農業生產與食品安全中的生物技術相關性

這本書探討了細胞色素P450單氧化酶的潛在價值；這是一類在植物代謝、防禦和生長中扮演重要角色的高度多功能酶。由於超過95%的植物P450仍未被功能性特徵化，本書作為理解它們在現代農業生物技術中多面向角色的綜合參考資料。

本書橋接了分子生物學與可持續農業，深入探討P450在激素生物合成、次級代謝、解毒以及植物與環境互動中的參與。它突顯了P450在提高作物生產力、增強對非生物和生物壓力（如乾旱、鹽分、病原體和重金屬）的抵抗力，以及通過基因工程實現精準育種中的日益重要性。

主要特點：

• 解釋植物中細胞色素P450基因的進化和功能多樣性


• 回顧它們在激素、脂肪酸、固醇、抗氧化劑和次級代謝物生物合成中的角色


• 討論P450介導的植物對壓力的反應：乾旱、高溫、病原體、洪水、寒冷等


• 介紹利用P450進行作物改良的尖端生物技術工具


• 將理論基礎與食品安全和環境可持續性的實際應用相結合

這本書是植物生物技術、農業微生物學、分子育種和環境壓力生理學領域的研究人員、研究生和行業專業人士的重要參考資料。它同時也是植物分子生物學和作物改良高級課程的核心教學文本。

通過結合科學深度與實際重點，本書提供了及時的見解，說明如何利用細胞色素P450酶來應對可持續農業和食品安全的全球挑戰。

Wadzani Palnam Dauda is a researcher, an academic mentor, and a life coach currently serving as a faculty member at the Federal University Gashua, Nigeria. His illustrious career is marked by over 130 scholarly publications reflecting his unwavering commitment to advancing scientific discourse. He was ranked number 10th by SciVal/SCOPUS in two different fields, Biological Sciences and Agricultural Science, among 500 prolific authors from 58 different countries in Africa. He holds esteemed positions, including Editorial Board memberships for Frontiers in Genome Editing, PLOS ONE, Springer Nature, Taylor & Francis, and Elsevier journals. Recognized for his scholarly eminence, he has received accolades and grants from prestigious organizations such as the Bill & Melinda Gates Foundation, UNESCO, Regeneron, American Phytopathological Society (APS), American Society of Microbiology (ASM), Department of Biotechnology (DBT) India, World Academy of Science (TWAS) Italy, Tertiary Education Trust Fund (TETFUND), and the prestigious M.J. Thirumalachar Merit Award for Young Scientists in 2022. His extensive research interests encompass diverse domains, including disease detection, mycotoxicology, agricultural microbiology, genome editing, and bioinformatics. His intellectual versatility is further highlighted by his memberships in renowned societies such as the American Society for Biochemistry and Molecular Biology (ASBMB), International Society for Computational Biology (ISCB), International Society for Molecular Plant-Microbe Interactions (IS-MPMI), Society for Applied Microbiology (SfAM), American Phytopathological Society (APS), American Society for Microbiology (ASM), the Nigerian Young Academy (NYA), and the Royal Society of Biology (RSB), UK. He has been invited as a keynote speaker at various national and international institutions and conferences, including the UNESCO International Centre for Biotechnology in Nsukka, Nigeria; the Doctoral Academy of Nigeria (DAN); National Open University of Nigeria (NOUN); University of Jos; Nnamdi Azikiwe University; Annamalai University; and several others. He holds the esteemed title of Fellow of the Society for Plant Research (FSPR). He is the Director of Research and Development at the Academic and Grant Writing Enclave (AGE).

Charles Oluwaseun Adetunji is a distinguished scholar in the Department of Microbiology, Faculty of Science, Edo State University, Uzairue (EDSU), Edo State, Nigeria. His research integrates biological techniques and microbial bioprocesses to advance sustainable development goals and foster agrarian transformation through impactful teaching, research, and community service. He currently serves as the Director of Research and Innovation and Chairman of the Grant Committee at EDSU, having previously held positions including Acting Director of Intellectual Property and Technology Transfer, Head of Department, Sub-Dean, and Dean of the Faculty of Science. He delivered the university's 11th Inaugural Lecture, titled "Microbial Biosphere: The Global Impact and Underexplored Currency," and was elected as a Senate representative for the Vice-Chancellor selection committee.

He began his career at the Nigerian Stored Products Research Institute (NSPRI), Ilorin, where he advanced from Research Officer II to Principal Scientist. His pioneering work improved food safety, shelf-life extension, and post-harvest technology. He later joined Landmark University, Omu-Aran, and served as a visiting fellow at the Hebrew University of Jerusalem and Wageningen Centre for Development and Innovation, Netherlands.

He is a fellow of the Royal Society of Biology (UK), the Biotechnology Society of Nigeria, the Nigerian Society of Microbiology, and the Nigerian Young Academy. He holds visiting professorships at Precious Cornerstone University, Trinity University, and the University of Johannesburg, among others. He serves as an external examiner and assessor for universities across Nigeria, Finland, South Africa, and Ethiopia and as an instructor at the University of the People, USA.

His global recognition includes being listed in Stanford University's "World's Top 2% Scientists" rankings (2023-2025) and named among ScholarGPS's 2024 Top 0.5% of Scholars globally in Life Sciences and Microbiology. With over 900 publications, including 60 books, 600 book chapters, and several patents, he has published in top journals such as Nature Medicine and The Lancet. His Google Scholar i10-Index exceeds 260. He is ranked first among Nigeria's top 500 prolific authors in Microbiology and Agricultural Sciences by SciVal/SCOPUS (Elsevier). He also serves as a book series editor with Wiley, Elsevier, Springer, and Taylor & Francis.

A global scientific leader, he has delivered keynote and plenary lectures at over 100 international conferences and reviews manuscripts for more than 100 journals, including Nature and PLOS One. His research contributions to the UN Sustainable Development Goals have been acknowledged by Elsevier.

He currently presides as President and Chairman of the Governing Council of the Nigerian Bioinformatics and Genomics Network Society and Vice-President of the Biotechnology Society of Nigeria. He has served on international committees, including the African Union Development Agency-NEPAD, American Society of Tropical Medicine and Hygiene, and Africa Research Excellence Fund (UK). Additionally, he consults for the Governments of Serbia and South Africa and coordinates the 1000 Scientific Trials Programme by Harvest Harmonics (USA) across 58 countries.

A mentor to numerous scholars globally, he guides postgraduate and postdoctoral researchers in translational and innovative science. Through his leadership, EDSU has signed over 30 international MoUs. As convener of the annual Recent Advances in Biotechnology Conference, he continues to inspire groundbreaking collaboration and innovation in microbiology, biotechnology, and bioinformatics.

**Wadzani Palnam Dauda** 是一位研究員、學術導師和生活教練，目前擔任尼日利亞聯邦大學 Gashua 的教職。他的卓越職業生涯以超過 130 篇學術出版物為標誌，反映出他對推進科學論述的堅定承諾。他在 SciVal/SCOPUS 的兩個不同領域——生物科學和農業科學中，於 58 個非洲國家的 500 位高產作者中排名第 10。他擔任多個期刊的編輯委員會成員，包括 *Frontiers in Genome Editing*、*PLOS ONE*、Springer Nature、Taylor & Francis 和 Elsevier。因其學術卓越而受到認可，他獲得了比爾和梅琳達·蓋茨基金會、聯合國教科文組織、Regeneron、美國植物病理學會 (APS)、美國微生物學會 (ASM)、印度生物技術部 (DBT)、意大利科學院 (TWAS)、高等教育信託基金 (TETFUND) 以及 2022 年的 M.J. Thirumalachar 年輕科學家優秀獎等多個知名組織的獎項和資助。他的廣泛研究興趣涵蓋多個領域，包括疾病檢測、真菌毒理學、農業微生物學、基因組編輯和生物信息學。他的智力多樣性還體現在他是美國生物化學與分子生物學學會 (ASBMB)、國際計算生物學學會 (ISCB)、國際分子植物-微生物相互作用學會 (IS-MPMI)、應用微生物學學會 (SfAM)、美國植物病理學會 (APS)、美國微生物學會 (ASM)、尼日利亞青年學院 (NYA) 和英國皇家生物學會 (RSB) 的成員。他曾受邀在多個國內外機構和會議上擔任主題演講者，包括尼日利亞 Nsukka 的聯合國教科文組織國際生物技術中心、尼日利亞博士學院 (DAN)、尼日利亞國立開放大學 (NOUN)、喬斯大學、南曼迪·阿齊基維大學、安納邁萊大學等。他擁有植物研究學會 (FSPR) 的榮譽會員稱號，並擔任學術與資助寫作中心 (AGE) 的研究與發展主任。

**Charles Oluwaseun Adetunji** 是尼日利亞埃多州大學 (EDSU) 科學院微生物學系的傑出學者。他的研究結合生物技術和微生物生物過程，以推進可持續發展目標，並通過有影響力的教學、研究和社區服務促進農業轉型。他目前擔任 EDSU 的研究與創新主任及資助委員會主席，曾擔任知識產權與技術轉移代理主任、系主任、副院長及科學院院長等職位。他發表了該大學的第 11 屆開幕講座，題為「微生物生物圈：全球影響與未被充分探索的貨幣」，並當選為副校長選拔委員會的參議院代表。

他在尼日利亞儲存產品研究所 (NSPRI) 開始了他的職業生涯，從研究官 II 升遷至首席科學家。他的開創性工作改善了食品安全、延長了保質期並推進了後收穫技術。之後，他加入了地標大學 (Landmark University)，並在耶路撒冷希伯來大學和荷蘭瓦赫寧根發展與創新中心擔任訪問研究員。

他是英國皇家生物學會、尼日利亞生物技術學會、尼日利亞微生物學會和尼日利亞青年學院的會員。他在珍貴基石大學、三一大學和約翰尼斯堡大學等多所大學擔任訪問教授。他還擔任尼日利亞、芬蘭、南非和埃塞俄比亞多所大學的外部考官和評估員，並在美國人民大學擔任講師。

他的全球認可包括被列入斯坦福大學的「全球前 2% 科學家」排名 (2023-2025)，並被 ScholarGPS 評選為 2024 年全球生命科學和微生物學領域的前 0.5% 學者。擁有超過 900 篇出版物，包括 60 本書、600 篇書章和多項專利，他在 *Nature Medicine* 和 *The Lancet* 等頂尖期刊上發表過文章。他的 Google Scholar i10-Index 超過 260。他在 SciVal/SCOPUS (Elsevier) 的尼日利亞前 500 位高產作者中排名第一，專注於微生物學和農業科學。他還擔任 Wiley、Elsevier、Springer 和 Taylor & Francis 的書系列編輯。

作為全球科學領袖，他在超過 100 個國際會議上發表主題演講和全體會議演講，並為超過 100 本期刊（包括 *Nature* 和 *PLOS One*）審稿。他對聯合國可持續發展目標的研究貢獻得到了 Elsevier 的認可。

他目前擔任尼日利亞生物信息學與基因組學網絡學會的會長及理事會主席，以及尼日利亞生物技術學會的副會長。他曾在非洲聯盟發展機構-NEPAD、美國熱帶醫學與衛生學會和非洲研究卓越基金 (UK) 等國際委員會任職。此外，他還為塞爾維亞和南非政府提供諮詢，並協調 Harvest Harmonics (USA) 在 58 個國家的 1000 科學試驗計劃。

作為全球眾多學者的導師，他指導研究生和博士後研究人員進行轉化和創新科學。通過他的領導，EDSU 簽署了超過 30 份國際合作備忘錄。作為年度生物技術最新進展會議的召集人，他持續激勵微生物學、生物技術和生物信息學領域的突破性合作與創新。