3D Organoids and Stem Cells in Regenerative Endodontics
暫譯: 再生根管治療中的3D器官類球與幹細胞
Tarique, Mohammed, Boreak, Nezar Mohammed
- 出版商: CRC
- 出版日期: 2026-09-22
- 售價: $4,780
- 貴賓價: 9.5 折 $4,541
- 語言: 英文
- 頁數: 186
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 1032964588
- ISBN-13: 9781032964584
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相關分類:
GAN 生成對抗網絡
尚未上市，無法訂購
商品描述
This book provides an overview of the latest advancements in the use of (three-dimensional) 3D organoids and stem cells for regenerative endodontics. It begins with an introduction to the foundational techniques for 3D organoid culture and explores cutting-edge developments in 3D bioprinting specifically tailored for dental applications. The book further examines the role of organoids in drug screening, toxicity testing, and the modulation of immune responses. It discusses the role of the microenvironment in organoid development, detailing how biophysical and biochemical factors, along with engineered niches, can influence the growth and functionality of organoids. The book reviews the use of various types of stem cells in regenerative endodontic therapies. The book explores the complex cellular and molecular interactions within organoid cultures, including stem cell-macrophage crosstalk and key signaling pathways involved in tissue regeneration. The role of the extracellular matrix (ECM) and different types of scaffolds, including nanofibrous, injectable scaffolds, bioinks, and decellularized extracellular matrices, are discussed for their importance in supporting 3D organoid integration and biocompatibility.
Key Features:
- Explores cutting-edge techniques for 3D organoid culture and bioprinting designed for dental applications
- Examines the role of organoids in drug screening, toxicity testing, and immune response modulation within endodontic research
- Highlights the importance of the microenvironment in organoid development
- Presents innovative scaffolds and biomaterials, such as nanofibrous scaffolds, bioinks, and decellularized extracellular matrices, for enhanced integration and biocompatibility in 3D organoid-based therapies
- Explores cutting-edge developments in 3D bioprinting technologies tailored for dental tissue engineering
This book is intended for researchers of tissue engineering, regenerative medicine, and endodontics and clinicians.
商品描述(中文翻譯)
這本書提供了有關使用三維 (3D) 器官類器官和幹細胞在再生根管治療中的最新進展概述。書中首先介紹了3D器官類器官培養的基礎技術，並探討了專為牙科應用量身定制的3D生物列印的前沿發展。該書進一步檢視了器官類器官在藥物篩選、毒性測試和免疫反應調節中的作用。它討論了微環境在器官類器官發展中的角色，詳細說明了生物物理和生化因素以及工程化小環境如何影響器官類器官的生長和功能。書中回顧了各類幹細胞在再生根管治療中的應用。該書探討了器官類器官培養中複雜的細胞和分子相互作用，包括幹細胞與巨噬細胞之間的交互作用以及涉及組織再生的關鍵信號通路。書中還討論了細胞外基質 (ECM) 和不同類型的支架，包括納米纖維支架、可注射支架、生物墨水和去細胞化的細胞外基質，這些在支持3D器官類器官整合和生物相容性方面的重要性。
主要特點：
- 探索專為牙科應用設計的3D器官類器官培養和生物列印的前沿技術
- 檢視器官類器官在藥物篩選、毒性測試和根管研究中的免疫反應調節作用
- 強調微環境在器官類器官發展中的重要性
- 提出創新的支架和生物材料，如納米纖維支架、生物墨水和去細胞化的細胞外基質，以增強3D器官類器官基礎治療中的整合和生物相容性
- 探索專為牙科組織工程量身定制的3D生物列印技術的前沿發展
這本書旨在為組織工程、再生醫學和根管治療的研究人員及臨床醫生提供參考。
作者簡介
Mohammed Tarique is a researcher and academic with expertise in molecular biology, biotechnology, and nanomedicine, working at Jamia Islamia. He holds a PhD from the International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, and has conducted post-doctoral research in parasite cell biology. Dr. Tarique is a member of several editorial boards. His research is published in high-impact journals, and he holds patents related to diabetic neuropathy treatment and glucose monitoring devices. Additionally, he has authored books on nanomedicine applications in cancer diagnosis and therapy, as well as the use of nanoparticles in tissue engineering and infectious diseases.
Nezar Mohammed Boreak is an academic and researcher specializing in the applications of stem cells and 3D organoids in endodontics. He earned his PhD in Dental Sciences and Clinical Certificate in Endodontics from Tohoku University, Japan, and furthered his expertise with a Certificate in Dental Implantology and the American Board in Implantology from New York University (NYU), USA. Currently, he serves as an Associate Professor and Consultant in Restorative Dentistry (Endodontics), College of Dentistry, Jazan University, Saudi Arabia. He earned his Doctor of Philosophy (PhD) in Endodontics from Tohoku University, Japan, and is American Board-certified in Implant Dentistry from New York University, USA. He previously served as Head of the Department, Vice Dean for Academic Affairs, and Head of the Alumni Unit. He is currently a member of the Curriculum Development Committee. He also served as the regional representative of the Saudi Endodontic Society in the Jazan Region and as the ICOI representative in Saudi Arabia. He is actively involved in teaching, clinical practice, research, and academic leadership in Endodontics and Restorative Dentistry.
作者簡介(中文翻譯)
**穆罕默德·塔里克**（Mohammed Tarique）是一位研究員和學者，專長於分子生物學、生物技術和奈米醫學，目前在賈米亞伊斯蘭大學（Jamia Islamia）工作。他擁有新德里國際基因工程與生物技術中心（ICGEB）的博士學位，並在寄生蟲細胞生物學方面進行了博士後研究。塔里克博士是多個編輯委員會的成員。他的研究發表在高影響力的期刊上，並持有與糖尿病神經病變治療和血糖監測設備相關的專利。此外，他還撰寫了有關奈米醫學在癌症診斷和治療中的應用，以及奈米顆粒在組織工程和傳染病中的使用的書籍。
**內扎爾·穆罕默德·博雷克**（Nezar Mohammed Boreak）是一位學者和研究員，專注於幹細胞和三維器官類似物在根管治療中的應用。他在日本東北大學獲得牙科科學博士學位及根管治療臨床證書，並在美國紐約大學（NYU）獲得牙科植牙證書和植牙美國委員會的認證。目前，他擔任沙烏地阿拉伯賈贊大學牙科學院的修復牙科（根管治療）副教授和顧問。他在日本東北大學獲得根管治療的哲學博士（PhD），並在美國紐約大學獲得植牙的美國委員會認證。他曾擔任系主任、學術事務副院長和校友單位主任，目前是課程發展委員會的成員。他還曾擔任沙烏地根管治療學會在賈贊地區的區域代表，以及沙烏地阿拉伯的ICOI代表。他積極參與根管治療和修復牙科的教學、臨床實踐、研究和學術領導。
