Coatings for Bioimplants and Their Applications
暫譯: 生物植入物的塗層及其應用

本書對生物植入物塗層的最新進展進行了徹底而詳細的探討。它強調了塗層在增強生物植入物的生物相容性和減少人體內不良反應方面所扮演的關鍵角色。主要主題包括機械性能、生物相容性、耐腐蝕性和抗菌效能。本書還從物理、化學和生物學的角度識別了改善塗層方法和協議的機會，涵蓋材料選擇、塗層過程和整體性能。

- 提供生物植入物塗層技術的綜合概述，涵蓋廣泛的材料和應用。
- 探討塗層在改善生物植入物生物相容性方面的重要性。
- 檢視植入行業中使用的材料的最新進展。
- 評估塗層在實驗室和實際條件下的性能。
- 討論生物活性塗層的新興趨勢，包括仿生和具有刺激響應行為的智能塗層。

本書適合在生物材料和塗層領域工作的研究生和研究人員。

K. Gobi Saravanan is currently working as Associate Professor (Research) and Head at Centre of Excellence for Additive Manufacturing, Sathyabama Institute of Science and Technology, Chennai, India. Currently, he is working in the field of 3D scaffolds, biomaterials, surface modification, antimicrobial coatings, corrosion protection of implant materials, bioactive and biocompatibility materials. He received various research grants including Department of biotechnology (DBT), Department of Science and Technology (DST), Indian Council of Medical Research (ICMR) All India Council for Technical Education (AICTE) and Indian Space Research Organization (ISRO), Govt. Of India with the cumulative funding of more than 2,10,00,000 INR. For his, credit, he has published more than 80 research articles in reputed International Journals with the citations of 1300 and h-index of 21 and holding 5 Indian patents with many national/international conference papers.

A.M Kamalan Kirubaharan is a researcher and ERA Talent fellow at Alexander Dubcek University in Trencin, Slovakia, presently working on thin films prepared through PVD and PECVD processes for optoelectronic applications. He has a background in ceramic coatings for corrosion and high temperature applications, ceramic matrix composites, and metal/ceramic thin films created using various physical vapor deposition (PVD) processes. He has extensive experience with thermal evaporation, electron beam evaporation (EBPVD), pulsed laser deposition (PLD), and RF/DC magnetron sputtering systems, along with strong expertise in XPS data analysis and surface characterization. Between 2019 and 2024, he led eight sponsored projects from the defense and aerospace sectors and secured institutional funding for product development and commercialization, demonstrating strong experience in industrial collaborative research. He has published 80+ papers with 1300+ citations and holds 9 Indian patents. He has served as a guest editor for Ceramics-MDPI, Coatings-MDPI, and Frontiers in Materials journals and a reviewer for a number of prestigious publications.

Ketul Popat is a Professor and Chair in the Department of Bioengineering at George Mason University. Prior to coming to George Mason University, he was Professor in Department of Mechanical Engineering/School of Biomedical Engineering at Colorado State University for 16 years. His work centers on using micro- and nanotechnology to design implants such as stents, heart valves, and hip/knee joint implants--that promote controlled, guided, and rapid healing. Specific research areas include Titanium Nanomaterials for Orthopedic Implants, Blood-Contacting Biomaterials for Cardiovascular Medical Devices, Polymeric Nanostructured Surfaces for Tissue Engineering Applications. He has authored over 175 peer-reviewed publications in journals such as Langmuir, Biomaterials, Journal of Orthopedic Research, Journal of Biomedical Materials Research, etc. and has and h-index of 54. He has presented his work at numerous national and international level conferences, has established strong research collaborations with researchers from Brazil, India, South Africa, Italy, etc. He received his Ph.D. in Bioengineering from University of Illinois at Chicago in 2003, M.S. in Chemical Engineering from Illinois Institute of Technology, Chicago in 2000 and B.E. in Chemical Engineering from M. S. University in India in 1998.

John Nesan, Director, Centre for Technology Assisted Reconstructive Surgery (CTARS) Pvt Ltd. is a maxillofacial surgeon by profession. He has over 17 years of experience in working with Rapid prototyping and stereolithographic models, and being associated with market leaders like Materialise, 3DSystems etc. CTARS is an exclusive healthcare 3D design and print unit. CTARS is the India's first and only 3D design and print unit for VSP (Virtual surgical planning) and 3D Splint fabrication for Orthognathic Surgery (correction of the jaws). CTARS is one of the very few units in India who design, print, and surgically operate on patients needing patient specific implants. John Nesan is well connected with a wide network of surgeons across India. CTARS is just one year into running and already has one patent and two more are in the process. He is also a member of the Association of Oral and Maxillofacial Surgeons of India, International Congress of Oral Implantologists, and Indian Society of Oral Implantologist. His passion is to bring the best in technology to needing patients in India. He is actively promoting the applications of 3D printing to the healthcare community. He regularly conducts CME and CDE programs on 3D printing in medical and dental universities across India

D. Dinesh Kumar is an Associate Professor and Head of the Centre for Nanoscience and Nanotechnology at Sathyabama Institute of Science and Technology, Chennai, India. He holds a Master of Science from Physics from Periyar University, a Master's in Nanoscience and Technology, and a Ph.D. from Anna University, Chennai. Dr Dinesh has received several prestigious fellowships, including CSIR-Senior Research Fellowship (SRF) and SERB-National Postdoctoral Fellowship (NPDF) awarded by various funding agencies of Government of India. He is the Principal Investigator of multiple funded research projects sponsored by DST-SERB, VSSC & LPSC-ISRO. His research focuses on the development of adaptive self-lubricating hard coatings for extreme environmental applications and biocompatible wear resistant coatings for orthopedic implants using Physical Vapor Deposition (PVD) techniques. He also investigates the phase transformation and oxidation kinetics of nickel-based superalloys used in space engine components. He has authored over 30 Web of Science-indexed publications, 07 book chapters, and 03 patents. He has guided several undergraduate and postgraduate students and currently supervises 04 doctoral scholars. His research contributions advance the understanding of nanostructured coatings and functional materials, building fundamental science with practical applications in aerospace, biomedical, and high-temperature engineering domains.

Sudip Mondal is an Assistant Professor at the Digital Healthcare Research Center, Pukyong National University, Busan, South Korea, specializing in Photomedicine. His pioneering research in photothermal and photodynamic therapies has significantly advanced disease treatment, with additional expertise in bioimaging using photoacoustic and fluorescence techniques. He received his Ph.D. in 2015 from the CSIR-Central Mechanical Engineering Research Institute and the National Institute of Technology Durgapur, India, followed by postdoctoral research at the Autonomous University of Puebla, Mexico (2015-2017). He was subsequently awarded the National Scientific Investigator Fellowship (CONACyT, Government of Mexico, 2017-2019) and served as a Research Professor (2017-2023) at Pukyong National University, South Korea. He has been continuously recognized from 2021 to 2025 in the Elsevier-Stanford University World's Top 2% Scientist List, reflecting his sustained global research impact. His research interests include Nano-Biomedicine, Tissue Engineering, and Cancer Therapy, focusing on the synthesis of nanostructured materials and their biomedical applications. Till date He has published over 75 international journal papers, holds 3 patents, and has an impressive Google Scholar h-index of 39, i10-index of 54, and 4,608 citations (as of October 2025). He serves as Guest Editor and reviewer for the International acclaimed publishing houses. He is also an active member of the External Ph.D. Review Committee and the Regional Research Laboratory Centre in Busan, South Korea.

**K. Gobi Saravanan** 目前擔任印度金奈Sathyabama科學與技術學院增材製造卓越中心的副教授（研究）及主任。他目前的研究領域包括3D支架、生物材料、表面改性、抗菌塗層、植入材料的防腐蝕保護以及生物活性和生物相容性材料。他獲得了多項研究資助，包括生物技術部（DBT）、科學與技術部（DST）、印度醫學研究委員會（ICMR）、全印度技術教育委員會（AICTE）和印度空間研究組織（ISRO）等機構的資助，累計資金超過21,000,000印度盧比。他已在國際知名期刊上發表超過80篇研究文章，引用次數達1300次，h指數為21，並持有5項印度專利及多篇國內/國際會議論文。

**A.M Kamalan Kirubaharan** 是斯洛伐克特倫欽亞歷山大·杜布切克大學的研究員及ERA人才研究員，目前專注於通過物理氣相沉積（PVD）和等離子體增強化學氣相沉積（PECVD）工藝製備的薄膜，用於光電應用。他擁有陶瓷塗層在防腐和高溫應用方面的背景，並且在使用各種物理氣相沉積（PVD）工藝製作金屬/陶瓷薄膜方面具有豐富經驗。他在熱蒸發、電子束蒸發（EBPVD）、脈衝激光沉積（PLD）和射頻/直流磁控濺射系統方面擁有廣泛的經驗，並在XPS數據分析和表面表徵方面具有強大的專業知識。在2019年至2024年間，他主導了來自國防和航空航天領域的八個贊助項目，並為產品開發和商業化獲得了機構資金，顯示出他在產業合作研究方面的豐富經驗。他已發表超過80篇論文，引用次數超過1300次，並持有9項印度專利。他曾擔任《Ceramics-MDPI》、《Coatings-MDPI》和《Frontiers in Materials》期刊的客座編輯，並為多個知名出版物擔任審稿人。

**Ketul Popat** 是喬治梅森大學生物工程系的教授及系主任。在來到喬治梅森大學之前，他在科羅拉多州立大學的機械工程系/生物醫學工程學院擔任教授16年。他的研究重點是利用微納米技術設計植入物，如支架、心臟瓣膜和髖/膝關節植入物，以促進受控、引導和快速癒合。具體研究領域包括用於骨科植入物的鈦納米材料、用於心血管醫療設備的血液接觸生物材料、以及用於組織工程應用的聚合物納米結構表面。他在《Langmuir》、《Biomaterials》、《Journal of Orthopedic Research》、《Journal of Biomedical Materials Research》等期刊上發表了超過175篇同行評審的出版物，h指數為54。他在多個國內和國際會議上展示了他的研究成果，並與來自巴西、印度、南非、意大利等國的研究人員建立了強有力的研究合作。他於2003年在伊利諾伊大學芝加哥分校獲得生物工程博士學位，2000年在伊利諾伊理工學院獲得化學工程碩士學位，1998年在印度M.S.大學獲得化學工程學士學位。

**John Nesan** 是技術輔助重建外科中心（CTARS）私人有限公司的主任，專業為顱面外科醫生。他在快速原型製作和立體光刻模型方面擁有超過17年的經驗，並與Materialise、3DSystems等市場領導者合作。CTARS是印度首個也是唯一的3D設計和打印單位，專注於虛擬手術規劃（VSP）和正顎手術（矯正下顎）的3D夾板製作。CTARS是印度少數幾個設計、打印並對需要特定患者植入物的患者進行手術的單位之一。John Nesan與印度各地的外科醫生建立了廣泛的聯繫網絡。CTARS運營僅一年，已擁有一項專利，另外兩項正在申請中。他還是印度口腔和顱面外科醫生協會、國際口腔植牙學會和印度口腔植牙學會的成員。他的熱情是將最好的技術帶給印度需要的患者，並積極推廣3D打印在醫療界的應用。他定期在印度的醫學和牙科大學舉辦有關3D打印的持續醫學教育（CME）和持續牙科教育（CDE）計劃。

**D. Dinesh Kumar** 是印度金奈Sathyabama科學與技術學院納米科學與納米技術中心的副教授及主任。他擁有來自Periyar大學的物理碩士學位、納米科學與技術碩士學位，以及來自金奈Anna大學的博士學位。Dinesh博士獲得了多項著名獎學金，包括由印度政府各資助機構頒發的CSIR高級研究獎學金（SRF）和SERB國家博士後獎學金（NPDF）。他是多個由DST-SERB、VSSC和LPSC-ISRO贊助的研究項目的首席研究員。他的研究重點是開發適應性自潤滑硬塗層，用於極端環境應用，以及使用物理氣相沉積（PVD）技術製作的生物相容性耐磨塗層，用於骨科植入物。他還研究用於太空引擎部件的鎳基超合金的相變化和氧化動力學。他已發表超過30篇Web of Science索引的出版物、7章書籍和3項專利。他指導了多名本科生和研究生，並目前指導4名博士生。他的研究貢獻推進了對納米結構塗層和功能材料的理解，建立了基礎科學與航空航天、生物醫學和高溫工程領域的實際應用。

**Sudip Mondal** 是韓國釜山國立大學數位醫療研究中心的助理教授，專攻光醫學。他在光熱和光動力療法方面的開創性研究顯著推進了疾病治療，並在使用光聲和螢光技術進行生物成像方面擁有額外專長。他於2015年在CSIR中央機械工程研究所和印度杜爾加普爾國立技術學院獲得博士學位，隨後在墨西哥普埃布拉自治大學進行博士後研究（2015-2017）。他隨後獲得了墨西哥政府的國家科學研究員獎學金（CONACyT，2017-2019），並在釜山國立大學擔任研究教授（2017-2023）。他自2021年至2025年持續被認可為Elsevier-史丹佛大學全球前2%科學家名單，反映了他持續的全球研究影響力。他的研究興趣包括納米生物醫學、組織工程和癌症療法，專注於納米結構材料的合成及其生物醫學應用。至今，他已發表超過75篇國際期刊論文，持有3項專利，並擁有令人印象深刻的Google Scholar h指數39，i10指數54，以及4608次引用（截至2025年10月）。他擔任國際知名出版商的客座編輯和審稿人，並且是釜山國立大學外部博士審查委員會和區域研究實驗室中心的活躍成員。