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商品描述
In a world where the quest for longevity has long been dominated by creams, supplements, and surgical interventions, a revolutionary shift is underway. Regeneration: The New Frontier in Anti-Aging delves into the emerging science that no longer seeks to slow aging--but to reverse it. This book explores how breakthroughs in cellular rejuvenation, tissue engineering, gene editing, and regenerative medicine are redefining what it means to grow old.
Drawing from cutting-edge research across molecular biology, biotechnology, and clinical practice, this work offers a panoramic view of how scientists and innovators are unlocking the body's innate capacity to repair, renew, and regenerate. What sets this book apart is its holistic integration of frontier science with ethical, social, and economic dimensions--bridging the lab and the living experience of aging.
Key Features:
- A comprehensive overview of regenerative biology and its implications for human longevity.
- In-depth analysis of breakthrough technologies such as stem cell therapy, CRISPR-based rejuvenation, and senolytic interventions.
- Case studies of leading laboratories, clinical trials, and biotech startups driving the field forward.
- Discussion of ethical challenges, accessibility, and future directions of age-reversal science.
- Insights from leading researchers, physicians, and futurists on what lies ahead.
Regeneration: The New Frontier in Anti-Aging is an essential read for medical professionals, researchers, bioethicists, and curious readers eager to understand how science is rewriting humanity's oldest story--aging itself.
商品描述(中文翻譯)
在這個長久以來都以乳霜、補充品與外科手術介入為主要延壽手段的世界中，一場革命性的轉變正在展開。《Regeneration: The New Frontier in Anti-Aging》深入探討新興科學：研究目標不再只是延緩老化，而是逆轉老化。本書探索細胞 rejuvenation（再生與年輕化）、組織工程、基因編輯與再生醫學等領域的突破，如何重新定義人類老去的意義。
本書汲取分子生物學、生物技術與臨床實務的前沿研究成果，全面呈現科學家與創新者如何解鎖人體與生俱來的修復、更新與再生能力。本書的獨特之處，在於將前沿科學與倫理、社會及經濟層面整合起來，串聯實驗室研究與人們實際經歷老化的生活體驗。
主要特色：
• 全面介紹再生生物學，以及其對人類長壽的影響。
• 深入分析幹細胞療法、以 CRISPR 為基礎的年輕化技術，以及 senolytic（衰老細胞清除）介入療法等突破性技術。
• 探討推動此領域持續發展的頂尖實驗室、臨床試驗與生技新創公司的案例。
• 討論逆齡科學所面臨的倫理挑戰、可及性問題與未來發展方向。
• 分享頂尖研究人員、醫師與未來學家的觀點，洞見這個領域的未來。
《Regeneration: The New Frontier in Anti-Aging》是醫療專業人員、研究人員、生物倫理學家，以及渴望了解科學如何改寫人類最古老故事——老化本身——的好奇讀者不可錯過的讀物。
作者簡介
Dr. Sandeep Kumar Singh is working as Assistant Professor in the All India Institute of Medical Sciences (AIIMS), Nagpur, MH, India. He is a well-trained neuroscientist with a strong background in Biochemistry and Biomedicine. He earned his PhD Degree in Biotechnology from the most prestigious institution, the "Capital of Knowledge" Banaras Hindu University, Varanasi, UP, India. His research interests include Neuroscience, Molecular Biology, Neurodegenerative diseases, Aging, Nutraceuticals and Nanomedicines. He has more than 12 years of experience in neuroscience research. He has used animal models' system to investigate the therapeutic potential for Alzheimer's disease using synthetic as well as natural compounds in Drosophila as a model system. Dr. Singh has published more than 65 articles in journals of international repute such as, (Journal of Alzheimer's disease, Pharmacological Research, Current Neuropharmacology, Open Biology (Royal Society), Neurotherapeutics, Neurotoxicity Research, Oxidative Medicine and Cellular Longevity, BBRC, Neurochemical Research, Neuroscience Letter, and Current Drug Metabolism etc.). He has been also credited with 12 book chapters and Editors of 5 books. He is also the member of editorial boards of several international journals related to field of neuroscience. He served as Guest Editor and handled a special issue in various International Journal related to the field of Neuroscience. He is also the member of several scientific societies viz. Indian Academy of Neurosciences, Alzheimer's and Related Disorders Society of India, American Academy of Neurology, International Society of Neurochemistry, American, and Society of Neurochemistry. Bentham Science Publisher (USA) has also appointed Dr. Singh as Bentham Ambassador. He has attended several scientific national and international conferences/symposium/workshops in India and abroad and presented his research work. As a resource person, he has delivered lectures and seminars in various schools and colleges across the country.
Shailendra Kumar Mishra is a molecular biologist with over five years of research experience in anti-ageing biology, longevity science, and age-related neurodegenerative disorders, with a particular emphasis on Alzheimer's disease. His research focuses on the molecular and genetic mechanisms underlying biological aging and their convergence with neurodegeneration, with the aim of identifying therapeutic strategies that promote healthy aging and extended health span.
Mishra has made notable contributions to aging research through his work on the hallmarks of aging and anti-ageing drug discovery. His scholarly contributions emphasize drug discovery and intervention strategies targeting genomic instability, mitochondrial dysfunction, cellular senescence, and altered intercellular communication. He co-authored the book Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging (Elsevier, 2022) and published the review article Therapeutic Antiaging Strategies (2022), which outlines key genetic, cellular, and pharmacological interventions targeting aging pathways. He is also the co-editor of the forthcoming volume Reverse Aging: Current Research and Future Directions (expected 2026).
In similar, his Alzheimer's disease research addresses neuroinflammation, immune response, biomarkers, cerebrovascular pathology, and nutraceutical-based interventions. His recent book chapters published by Academic Press, Elsevier (2024) focus on biomarkers for Alzheimer's diagnosis, cerebrovascular targets, nutraceuticals, and genome-editing approaches for neurodegenerative diseases. Mishra is the co-founder of the Indian Scientific Education and Technology (ISET) Foundation and actively promotes interdisciplinary research and scientific education in aging and brain health.
作者簡介(中文翻譯)
Dr. Sandeep Kumar Singh 任職於印度那格浦爾（Nagpur, MH, India）的全印度醫學科學研究院（All India Institute of Medical Sciences, AIIMS），擔任助理教授。他是一名受過良好訓練的神經科學家，在生物化學與生物醫學領域具備深厚背景。他於印度北方邦瓦拉納西（Varanasi, UP, India）最負盛名、素有「知識之都」之稱的 Banaras Hindu University 取得生物技術博士學位。他的研究興趣包括神經科學、分子生物學、神經退化性疾病、老化、營養保健品與奈米醫學。他在神經科學研究領域擁有超過 12 年的經驗。他曾使用動物模型系統，並以果蠅（Drosophila）作為模式系統，利用合成化合物與天然化合物，探討其治療阿茲海默症的潛力。Singh 博士已在國際知名期刊發表超過 65 篇論文，例如 Journal of Alzheimer's Disease、Pharmacological Research、Current Neuropharmacology、Open Biology（Royal Society）、Neurotherapeutics、Neurotoxicity Research、Oxidative Medicine and Cellular Longevity、BBRC、Neurochemical Research、Neuroscience Letters 及 Current Drug Metabolism 等。他也參與撰寫了 12 本書籍章節，並擔任 5 本書的編輯。他同時是多本神經科學相關國際期刊編輯委員會的成員。他曾擔任 Guest Editor，並負責處理多本神經科學相關國際期刊的特刊。他也是多個科學學會的會員，包括 Indian Academy of Neurosciences、Alzheimer's and Related Disorders Society of India、American Academy of Neurology、International Society of Neurochemistry、American Society of Neurochemistry。Bentham Science Publishers（USA）亦任命 Singh 博士為 Bentham Ambassador。他曾在印度及海外參加多場國內與國際科學會議、研討會及工作坊，並發表研究成果。作為專題講者，他曾在全國各地的多所學校與大專院校進行演講及研討會。
Shailendra Kumar Mishra 是一名分子生物學家，在抗老化生物學、長壽科學及與年齡相關的神經退化性疾病領域擁有超過五年的研究經驗，尤其專注於阿茲海默症。他的研究聚焦於生物老化背後的分子與遺傳機制，以及這些機制與神經退化之間的交集，旨在找出能促進健康老化並延長健康壽命的治療策略。
Mishra 透過對老化特徵（hallmarks of aging）及抗老化藥物開發的研究，對老化研究做出了重要貢獻。他的學術成果著重於以基因體不穩定性、粒線體功能障礙、細胞衰老及細胞間通訊異常為標的的藥物開發與介入策略。他與他人合著了 Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging（Elsevier，2022），並發表評論文章 Therapeutic Antiaging Strategies（2022）；該文概述了針對老化途徑的關鍵遺傳、細胞與藥理學介入措施。他也是即將出版的專書 Reverse Aging: Current Research and Future Directions（預計於 2026 年出版）的共同編輯。
同樣地，他在阿茲海默症方面的研究涵蓋神經發炎、免疫反應、生物標記、腦血管病理，以及以營養保健品為基礎的介入措施。他近期由 Academic Press、Elsevier 出版的書籍章節（2024）聚焦於阿茲海默症診斷生物標記、腦血管標的、營養保健品，以及神經退化性疾病的基因組編輯方法。Mishra 是 Indian Scientific Education and Technology（ISET）Foundation 的共同創辦人，並積極推動老化與腦部健康領域的跨學科研究及科學教育。
