Biophysical Models of Radiation Action
暫譯: 輻射作用的生物物理模型
Nikjoo, Hooshang, Taleei, Reza
- 出版商: CRC
- 出版日期: 2026-10-27
- 售價: $5,080
- 貴賓價: 9.5 折 $4,826
- 語言: 英文
- 頁數: 418
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 1041073259
- ISBN-13: 9781041073253
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相關分類:
物理學 Physics
海外代購書籍(需單獨結帳)
商品描述
Three distinct processes occur in sequence when human cells encounter environmental toxins like radiation. Firstly, physical damage occurs as radiation particles deposit energy into cellular structures. A chemical reaction follows, as this energy creates fast-moving ions that attack and damage DNA. Lastly a biological response is initiated as the cells attempt to repair the damage.
Understanding this interaction is essential for assessing radiation risks, developing cancer treatments, and protecting human health.
Unlike traditional texts that focus solely on mathematical modelling, this work integrates the physics, chemistry, and biology of radiation damage into a unified framework. It provides researchers, students, and professionals with the tools to understand not just what happens when cells are irradiated, but how and why.
It presents comprehensive mathematical models for all three parts of this process, complete with computer programs that generate testable predictions. By comparing simulated data with experimental results, this book validates theoretical frameworks and bridges the gap between abstract mathematics and biological reality.
Each chapter is complemented by computer code, intended to support and encourage learning and understanding of the knowledge underlying biophysics and biology of this topic.
This will be a valuable guide for final year master's and PhD students in radiation related topics in addition to postdoctoral researchers seeking to understand the fundamental mechanisms of radiation-induced cellular damage. It will also be a useful reference for radiobiologists, medical physicists, and radiation oncologists involved in teaching and developing mathematical models in radiobiology.
Key features:
- Written by one of the world's leading experts in biophysical modelling of radiation interaction with living material.
- Offers researchers, teachers and students in the field a resource and programs for computer experimentation and learning.
- Accompanied by computer codes used for the development of the models presented.
商品描述(中文翻譯)
當人類細胞遭遇輻射等環境毒物時，會依序發生三個截然不同的過程。首先，輻射粒子將能量沉積於細胞結構中，造成物理損傷。接著發生化學反應，這些能量會產生高速移動的離子，進而攻擊並損傷 DNA。最後，細胞會嘗試修復損傷，並啟動生物反應。
了解這些交互作用，對於評估輻射風險、開發癌症治療方法，以及保護人類健康都至關重要。
不同於僅著重於數學建模的傳統著作，本書將輻射損傷的物理、化學與生物學整合至一個統一的架構中。本書為研究人員、學生與專業人士提供所需工具，使其不僅能了解細胞受到輻射照射時會發生什麼，也能理解這些現象如何發生，以及為什麼會發生。
本書針對上述過程的三個部分，提出完整的數學模型，並搭配可產生可驗證預測結果的電腦程式。透過比較模擬資料與實驗結果，本書驗證理論架構，並彌合抽象數學與生物現實之間的落差。
每一章皆搭配電腦程式碼，旨在支援並鼓勵讀者學習與理解本主題背後的生物物理學與生物學知識。
本書將是輻射相關領域碩士班最後一年學生與 PhD 學生，以及希望了解輻射誘發細胞損傷基本機制之博士後研究人員的重要指南。此外，對於參與放射生物學教學與數學模型開發的放射生物學家、醫學物理學家及放射腫瘤科醫師而言，本書也將是實用的參考資料。
主要特色：
• 由全球領先的生物物理建模專家之一撰寫，探討輻射與生命物質之間的交互作用。
• 為該領域的研究人員、教師與學生提供電腦實驗與學習所需的資源及程式。
• 隨書附上用於開發書中模型的電腦程式碼。
作者簡介
Hooshang Nikjoo is a retired Professor of Radiation Biophysics and currently a research visitor in the Department of Physiology, Anatomy and Genetics at the University of Oxford. He has lived in Oxford for more than 40 years. Previously, he spent many successful years at the Karolinska Institutet, Stockholm, the NASA Johnson Space Center in Houston, Texas, and the MRC Radiobiology/Genome Stability Unit in Harwell. His scientific work is reflected in the chapters of this book. Outside academia, he enjoys cycling and dancing Argentine tango.
Reza Taleei is an Associate Professor of Medical Physics and Director of Brachytherapy at Thomas Jefferson University. He earned his PhD in Medical Radiation Physics from the Karolinska Institutet. His work spans radiobiology, Monte Carlo-based radiation modeling, DNA Damage and Repair, and clinical medical physics. He has published widely, contributed to multiple book chapters, and serves as Associate Editor of Radiation Research
作者簡介(中文翻譯)
Hooshang Nikjoo 是退休的放射生物物理學教授，目前擔任 Oxford University 生理學、解剖學與遺傳學系的訪問研究員。他在 Oxford 居住超過 40 年。過去，他曾在 Stockholm 的 Karolinska Institutet、位於 Texas 州 Houston 的 NASA Johnson Space Center，以及 Harwell 的 MRC 放射生物學／基因組穩定性部門，度過多年卓有成效的研究生涯。他的科學研究成果反映於本書各章之中。在學術研究之外，他喜歡騎自行車和跳阿根廷探戈。
Reza Taleei 是 Thomas Jefferson University 的醫學物理學副教授兼近接治療部主任。他在 Karolinska Institutet 取得醫學輻射物理學博士學位。其研究涵蓋放射生物學、以 Monte Carlo 為基礎的輻射建模、DNA 損傷與修復，以及臨床醫學物理學。他發表了廣泛的研究成果，參與撰寫多本書籍的章節，並擔任 Radiation Research 的副主編。
