Artificial Intelligence and Precision Fermentation for Sustainable Energy Production
暫譯: 人工智慧與精準發酵：永續能源生產

人工智慧與精準發酵：永續能源生產

《人工智慧與精準發酵：永續能源生產》探討 AI 與精準發酵在永續生物能源生產上的融合。內容涵蓋理論基礎與實務應用，說明如何運用 AI 工具最佳化微生物菌株，並即時監控生物反應器。

採用基因工程微生物的精準發酵技術，可克服傳統發酵的限制，將農業廢棄物轉化為生質燃料與生物化學品。本書：

- 涵蓋規模放大、法規架構、倫理考量與資料限制等實作挑戰
- 整合人工智慧（Artificial Intelligence）與機器學習（Machine Learning）於生物製程與生物能源中的應用
- 討論生物反應器的預測建模與即時監控
- 介紹用於設計與最佳化精準發酵酵素的新型 AI 工具，包括生成模型與分子動力學模擬
- 涵蓋已開發市場與新興市場中由 AI 驅動的生物能源解決方案案例研究，並收錄不同國家的政策架構、法規挑戰與經濟可行性等內容

本書適合生物製程、AI、發酵技術與再生能源工程領域的研究生及研究人員閱讀。

Ooi Chien Wei is an Associate Professor and Head of the Department of Chemical Engineering at Monash University Malaysia, and Deputy Director of the Centre for Net Zero Technology working within the BIO-Trans theme. His expertise centres on bioprocess design and biocatalysis, with emphasis on integrated microbial fermentation systems and predictive bioprocess models for efficient expression of industrial enzymes and recombinant proteins. Recent research targets biomass biotransformation using efficient pretreatment and enzymatic hydrolysis to generate platform chemicals; he also advances bio-derived ionic liquids and stimuli-responsive polymers for novel bioprocesses, bioseparations and biosensing. Beyond core bioprocessing, his group develops food-grade emulsions and green extraction technologies for food-waste valorisation and recovery of phytonutrients from microalgae and agro-residues, and collaborates with industry on smart hydrogels and biocatalytic route re-engineering, spanning enzyme engineering, production and molecular dynamics simulations. He has been a lead editor of a book published by CRC Press and has contributed book chapters to Academic Press. He has published more than 138 ISI-indexed journal articles, holds six patents across bioprocess technology, biomass processing and smart hydrogel applications, and has secured over RM 1 million in competitive government and industry funding. His work integrates mechanistic insight, process development, scale-up, techno-economic analysis, and life-cycle assessment, underpinning collaborative, industry-facing research in bioprocessing.

Ramalakshmi Subbarayalu is an Assistant Professor (Research) in the Department of Bioengineering at Vels Institute of Science, Technology and Advanced Studies (VISTAS), Chennai. Her expertise lies in translational bioengineering, with a focus on microbial systems and advanced characterization techniques, including fluorescence microscopy, SEM, AFM, and biosensing technologies. She has received prestigious fellowships such as the Australian Endeavour Fellowship and JASSO fellowship, Japan. She has published in reputed journals while holding patents in diagnostic device development. She has also contributed several book chapters to leading publishers including Springer Nature and CRC Press, and has secured competitive research funding, demonstrating her ability to translate laboratory innovations into impactful, field-deployable technologies aligned with One Health and antimicrobial resistance mitigation.

Lo Sewn Cen is a Research Fellow at the Future Centre for Net-Zero Technology, Monash University Malaysia. She drives innovation in sustainable biotechnologies. Her work focuses on transforming chemical and agricultural waste into high-value products, supporting net-zero carbon goals and the circular bioeconomy. Dr. Lo has led and contributed to numerous industry-linked projects, bridging fundamental research with real-world applications. She brings extensive expertise in genetic engineering, bioprocessing, biotransformation, and sustainable process design, integrating innovative microbial platforms with process optimisation to enable efficient and scalable bioconversion systems.

N. Gnanasankaran is an Associate Professor in the Department of Computer Science, Thiagarajar College, Madurai, Tamil Nadu, India. His areas of research specialization include Software Engineering, SQA, SQM, Data Science, Machine Learning, Big Data Analytics, and IoT. He has contributed more than 35 research articles in Scopus and Web of Science Indexed journals/ conferences. He has contributed four edited book volumes and has published 43 book chapters in prominent publishers. He holds eight patent work (two Indian design and one utility patent/ three UK design patent/ two German utility patent) in the field of Cyber Security, IoT, Drone Technology and Healthcare.

Ooi Chien Wei 是 Monash University Malaysia 化學工程系副教授兼系主任，也是 Future Centre for Net-Zero Technology 副主任，負責 BIO-Trans 主題的相關工作。他的專長集中於生物製程設計與生物催化，尤其著重於整合式微生物發酵系統，以及用於高效率表現工業酵素與重組蛋白的預測性生物製程模型。近期研究以生質物轉化為主，透過高效的前處理與酵素水解生成平台化學品；此外，他也致力於開發生物衍生離子液體與刺激響應型聚合物，應用於新型生物製程、生物分離與生物感測。在核心生物製程之外，其研究團隊也開發食品級乳液與綠色萃取技術，用於食品廢棄物高值化，以及從微藻與農業殘餘物中回收植物營養素；同時與業界合作開發智慧水凝膠及生物催化路徑再工程技術，研究範圍涵蓋酵素工程、生產與分子動力學模擬。他曾擔任一本由 CRC Press 出版之書籍的主編，並為 Academic Press 出版的書籍撰寫章節。他已發表超過 138 篇收錄於 ISI 索引的期刊論文，並在生物製程技術、生質物處理及智慧水凝膠應用等領域持有六項專利；此外，也取得超過 100 萬馬來西亞令吉（RM）的政府與業界競爭型研究經費。他的研究整合機理洞察、製程開發、放大、技術經濟分析與生命週期評估，為以合作及產業應用為導向的生物製程研究奠定基礎。

Ramalakshmi Subbarayalu 是 Vels Institute of Science, Technology and Advanced Studies（VISTAS，位於 Chennai）生物工程系的研究助理教授。她專長於轉譯生物工程，研究重點涵蓋微生物系統與先進表徵技術，包括螢光顯微鏡、SEM、AFM 及生物感測技術。她曾獲得 Australian Endeavour Fellowship 及日本 JASSO fellowship 等著名獎學金。她曾在知名期刊發表論文，並持有診斷裝置開發相關專利。此外，她也為 Springer Nature、CRC Press 等知名出版社出版的書籍撰寫多個章節，並取得競爭型研究經費，展現其將實驗室創新轉化為具影響力且可部署於實際場域之技術的能力；這些技術與 One Health 理念及抗微生物藥物抗藥性防治目標相符。

Lo Sewn Cen 是 Monash University Malaysia Future Centre for Net-Zero Technology 的研究員，致力於推動永續生物技術的創新。她的研究聚焦於將化學與農業廢棄物轉化為高附加價值產品，以支持淨零碳排目標與循環生物經濟。Lo 博士曾領導並參與多項與產業合作的計畫，致力於連結基礎研究與實際應用。她在基因工程、生物製程、生物轉化及永續製程設計方面具備廣泛專業，並將創新的微生物平台與製程最佳化相結合，以實現高效率且可擴展的生物轉化系統。

N. Gnanasankaran 是印度 Tamil Nadu 州 Madurai Thiagarajar College 電腦科學系的副教授。他的研究專長包括軟體工程、SQA、SQM、資料科學、Machine Learning、Big Data Analytics 及 IoT。他已在 Scopus 與 Web of Science 收錄的期刊及研討會中發表超過 35 篇研究論文。他曾參與編輯四本書籍，並在知名出版社出版的書籍中發表 43 個章節。他持有八項專利，包括兩項印度設計專利、一項印度實用專利、三項英國設計專利，以及兩項德國實用專利，研究領域涵蓋 Cyber Security、IoT、Drone Technology 與 Healthcare。