Bayesian Approaches to Clinical Trials and Health Technology Assessment

Bayesian methods have increasingly become the standard statistical approach in medical research. Their use is encouraged by regulatory bodies, such as the FDA, due to the versatility of the methodology. This new edition of the leading text on Bayesian approaches to clinical trials has been extensively revised and updated to reflect recent developments in the field, and places greater emphasis on health technology assessment. New material on missing data and longitudinal analysis issues is also included. The book is introductory in nature and covers a broad array of essential topics.

The first edition received universal praise. This update is designed to meet the developing needs of statisticians in the pharmaceutical industry, and anyone involved in conducting clinical trials and HTA work.

貝葉斯方法在醫學研究中越來越成為標準統計方法。由於這種方法的多功能性，監管機構如FDA鼓勵使用。這本領先的貝葉斯臨床試驗方法的新版已經經過廣泛修訂和更新，以反映該領域的最新發展，並更加強調健康技術評估。書中還包括了有關缺失數據和長期分析問題的新材料。這本書是入門性質的，涵蓋了廣泛的基本主題。

第一版獲得了普遍好評。這次更新旨在滿足製藥行業統計學家和從事臨床試驗和健康技術評估工作的人的不斷發展的需求。