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商品描述
Comprehensive coverage of major families of viruses, including human pathogens and viruses of organisms from bacteria to plants, with updated information on antiviral drugs, vaccines, antiviral immunity, and gene therapy
Fundamentals of Molecular Virology is a textbook designed for university students learning about viruses at the undergraduate or graduate levels. Chapters contributed by prominent virologists cover many of the major virus families. Each chapter is designed to tell a story about the viruses covered, including information on discovery, diseases and pathogenesis, virus structure, steps in replication, and interaction with cellular signaling pathways. This approach portrays the "personality" of each virus, helping students to learn the material and build up their knowledge of virology starting with smaller and simpler viruses and proceeding to more complex viruses.
Major importance is given to viruses that infect humans and cause disease, but coverage is broad, including viruses of bacteria, Archaea, algae, invertebrates, and plants. Information boxes highlight applications and research directions of particular significance. Chapters conclude with sections presenting fundamental concepts, review questions, and lists of key terms, which are defined in a glossary at the end of the book.
This 3rd edition of Fundamentals of Molecular Virology includes detailed information on the recent COVID-19 pandemic and mRNA vaccine technology, additional sections on pathogenic herpesviruses, and updates on recent outbreaks of Zika virus, Ebola virus and mpox diseases. New chapters describe hepatitis C virus, rhabdoviruses, viruses of invertebrates, oncolytic viruses, and virus-mediated gene therapy. All chapters, including those on innate and adaptive immune responses to virus infections, virus vaccines, and antiviral agents, were revised and updated.
商品描述(中文翻譯)
全面涵蓋主要病毒家族，包括人類病原體及從細菌到植物的生物病毒，並提供有關抗病毒藥物、疫苗、抗病毒免疫及基因治療的最新資訊
分子病毒學基礎 是一本為大學本科或研究生學習病毒的學生設計的教科書。由知名病毒學家撰寫的章節涵蓋了許多主要的病毒家族。每一章都旨在講述所涵蓋病毒的故事，包括發現、疾病及發病機制、病毒結構、複製步驟以及與細胞信號通路的互動。這種方法描繪了每種病毒的「個性」，幫助學生學習材料，並從較小且簡單的病毒開始，逐步建立對病毒學的知識，最終進入更複雜的病毒。
特別重視感染人類並引起疾病的病毒，但涵蓋範圍廣泛，包括細菌、古菌、藻類、無脊椎動物及植物的病毒。資訊框突顯了特別重要的應用及研究方向。章節結尾提供基本概念、複習問題及關鍵術語列表，這些術語在書末的詞彙表中有定義。
這本分子病毒學基礎的第三版包含有關近期COVID-19疫情及mRNA疫苗技術的詳細資訊，增加了有關致病性皰疹病毒的部分，以及對近期茲卡病毒、埃博拉病毒和mpox疾病疫情的更新。新章節描述了丙型肝炎病毒、彈狀病毒、無脊椎動物病毒、腫瘤溶解病毒及病毒介導的基因治療。所有章節，包括有關病毒感染的先天及適應性免疫反應、病毒疫苗及抗病毒藥物的內容，都已修訂和更新。
作者簡介
Christopher D. Richardson is Professor, Department of Microbiology & Immunology, Department of Pediatrics, Dalhousie University, Canada. Dr. Chris Richardson is a molecular virologist with 35 years of experience working with a variety of viruses. He earned his PhD at the University of British Columbia and did postdoctoral work at The Rockefeller University and the National Institutes of Health (Bethesda, USA). He previously held faculty positions at the National Research Council of Canada, McGill University, and the University of Toronto.
Nicholas H. Acheson is Emeritus Professor of Microbiology & Immunology at McGill University, Quebec, Canada. He earned his PhD from The Rockefeller University and was a postdoctoral fellow at the Swiss Institute for Experimental Cancer Research (Lausanne) and Institut Pasteur (Paris). He carried out research on Semliki Forest virus and mouse polyomavirus, and taught a virology course for advanced undergraduate students at McGill University.
作者簡介(中文翻譯)
克里斯多福·D·理查森是加拿大達爾豪斯大學微生物學與免疫學系及兒科系的教授。克里斯·理查森博士是一位分子病毒學家，擁有35年的各類病毒研究經驗。他在不列顛哥倫比亞大學獲得博士學位，並在洛克菲勒大學及美國國立衛生研究院（貝塞斯達）進行博士後研究。他曾在加拿大國家研究委員會、麥吉爾大學及多倫多大學擔任教職。
尼古拉斯·H·艾奇森是加拿大魁北克省麥吉爾大學微生物學與免疫學的名譽教授。他在洛克菲勒大學獲得博士學位，並曾在瑞士實驗癌症研究所（洛桑）及巴斯德研究所（巴黎）擔任博士後研究員。他對塞姆利基森林病毒和小鼠多瘤病毒進行了研究，並在麥吉爾大學教授高年級本科生的病毒學課程。
