BioBuilder (Paperback)

Natalie Kuldell, Rachel Bernstein, Karen Ingram, Kathryn M Hart

  • 出版商: O'Reilly
  • 出版日期: 2015-07-28
  • 定價: $1,750
  • 售價: 8.0$1,400
  • 語言: 英文
  • 頁數: 238
  • 裝訂: Paperback
  • ISBN: 1491904291
  • ISBN-13: 9781491904299
  • 相關分類: 生物資訊 Bioinformatics資訊科學
  • 立即出貨 (庫存=1)

商品描述

Today’s synthetic biologists are in the early stages of engineering living cells to help treat diseases, sense toxic compounds in the environment, and produce valuable drugs. With this manual, you can be part of it. Based on the BioBuilder curriculum, this valuable book provides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories. It also serves as an introduction to the field for science and engineering enthusiasts.

Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering that researchers are exploring in labs throughout the world. These lessons will empower teachers and students to explore and be part of solving persistent real-world challenges.

  • Learn the fundamentals of biodesign and DNA engineering
  • Explore important ethical issues raised by examples of synthetic biology
  • Investigate the BioBuilder labs that probe the design-build-test cycle
  • Test synthetic living systems designed and built by engineers
  • Measure several variants of an enzyme-generating genetic circuit
  • Model "bacterial photography" that changes a strain’s light sensitivity
  • Build living systems to produce purple or green pigment
  • Optimize baker’s yeast to produce ?-carotene

商品描述(中文翻譯)

今天的合成生物學家正處於利用活體細胞來治療疾病、感應環境中的有毒化合物和生產有價值的藥物的早期階段。透過這本手冊,您可以成為其中的一員。基於BioBuilder課程,這本寶貴的書籍為中學和大學課堂以及實驗室提供了開放式、模塊化、實踐性的合成生物學教學。同時,它也是科學和工程愛好者進入這個領域的入門指南。

BioBuilder是在麻省理工學院與屢獲殊榮的高中教師合作下開發的,它教授新興合成生物學領域的基礎概念,以及研究人員在全球各地實驗室中正在探索的生物工程的關鍵方面。這些課程將使教師和學生能夠探索並參與解決持續存在的現實世界挑戰。

本書內容包括:
- 學習生物設計和DNA工程的基礎知識
- 探索合成生物學案例所引發的重要倫理問題
- 調查BioBuilder實驗室中的設計-構建-測試循環
- 測試工程師設計和構建的合成生物系統
- 測量幾種變異的酶生成基因電路
- 模擬改變菌株光敏度的“細菌攝影”
- 構建生物系統以產生紫色或綠色色素
- 優化麵包酵母以產生β-胡蘿蔔素