Anti-Coronavirus Marine Bioactive Compounds
暫譯: 抗冠狀病毒海洋生物活性化合物
Chen, Jen-Tsung
- 出版商: Apple Academic Press
- 出版日期: 2025-11-25
- 售價: $9,260
- 貴賓價: 9.5 折 $8,797
- 語言: 英文
- 頁數: 440
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 1779640102
- ISBN-13: 9781779640109
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相關分類:
生物資訊 Bioinformatics
海外代購書籍(需單獨結帳)
商品描述
This unique volume summarizes emerging approaches based on in silico, in vitro, in vivo, and clinical studies to uncover the potential and the underlying mechanisms of diverse marine bioactive compounds to inhibit SARS-CoV-2 and its variants and, hence, pave the way for drug discovery devoted to the management of COVID-19.
Investigating a range of natural compounds for their anti-SARS-CoV-2 activity, this volume offers in-depth insights into molecular mechanisms that can inhibit viral/host protein targets of SARS-CoV-2. It highlights the action of marine bioactive compounds based on advanced bioinformatics tools such as molecular docking, computer simulation, and systems pharmacology, as well as multiple omics and high-throughput technologies. Chapters discuss the modes of action by selected marine polysaccharides, terpenoids, astaxanthin, and an indole-alkaloid (holyrine A) for combating SARS-CoV-2, and propose their potential role in COVID-19 management. Finally, a chapter discusses the role of marine bioactive compounds that include some traditional remedies from Southeast Asia for combating SARS-CoV-2 infection.
Providing valuable knowledge based on state-of-the-art literature that highlights the anti-SARS-CoV-2 activity of marine bioactive compounds, this work will be an important resource for researchers, professors, and experts in diverse sub-fields of life sciences, such as virology, pharmaceutical science and drug discovery, medical research, biochemistry, bioinformatics, biomedical science, computational biology, epidemiology, and other areas. The book presents approaches that are potentially useful for the management of global public health and can support the goal of establishing "Good Health and Well-Being," which is one of the "Sustainable Development Goals (SDGs) 2030" of the United Nations.
商品描述(中文翻譯)
這本獨特的著作總結了基於計算機模擬（in silico）、體外（in vitro）、體內（in vivo）和臨床研究的新興方法，以揭示各種海洋生物活性化合物抑制SARS-CoV-2及其變異株的潛力及其潛在機制，從而為針對COVID-19管理的藥物發現鋪平道路。
本書調查了一系列天然化合物的抗SARS-CoV-2活性，提供了對能夠抑制SARS-CoV-2病毒/宿主蛋白靶點的分子機制的深入見解。它強調了基於先進生物信息學工具（如分子對接、計算機模擬和系統藥理學）以及多重組學和高通量技術的海洋生物活性化合物的作用。各章節討論了選定的海洋多醣、萜類化合物、蝦青素和一種吲哚生物鹼（holyrine A）對抗SARS-CoV-2的作用模式，並提出它們在COVID-19管理中的潛在角色。最後，一章討論了包括一些來自東南亞的傳統療法在內的海洋生物活性化合物在對抗SARS-CoV-2感染中的作用。
本書基於最前沿的文獻提供了有價值的知識，突顯了海洋生物活性化合物的抗SARS-CoV-2活性，將成為生命科學各個子領域的研究人員、教授和專家的重要資源，如病毒學、藥學和藥物發現、醫學研究、生物化學、生物信息學、生物醫學科學、計算生物學、流行病學等。本書提出的各種方法對於全球公共衛生管理可能具有實用價值，並能支持建立「良好健康與福祉」的目標，這是聯合國「2030可持續發展目標（SDGs）」之一。
作者簡介
Jen-Tsung Chen, PhD, is a Professor of Cell Biology at the National University of Kaohsiung in Taiwan, where he teaches genomics, proteomics, plant physiology, and plant biotechnology. Dr. Chen's research interests include bioactive compounds, chromatography techniques, plant molecular biology, plant biotechnology, bioinformatics, and systems pharmacology. He is an active editor of academic books and journals in an effort to advance the exploration of multidisciplinary knowledge involving plant physiology, plant biotechnology, nanotechnology, ethnopharmacology, systems biology, and drug discovery. He serves as an editorial board member and a guest editor for several reputed journals. Dr. Chen has published books in collaboration with international publishers on diverse topics such as drug discovery, herbal medicine, medicinal biotechnology, nanotechnology, bioengineering, plant functional genomics, plant speed breeding, CRISPR-based plant genome editing, and artificial intelligence. He has been included in the list of the World's Top 2% Scientists 2023 by Stanford University.
作者簡介(中文翻譯)
陳仁宗博士是台灣高雄國立大學的細胞生物學教授，教授基因組學、蛋白質組學、植物生理學和植物生物技術。陳博士的研究興趣包括生物活性化合物、色譜技術、植物分子生物學、植物生物技術、生物資訊學和系統藥理學。他積極擔任學術書籍和期刊的編輯，以推進涉及植物生理學、植物生物技術、奈米技術、民族藥理學、系統生物學和藥物發現的多學科知識探索。他擔任多本知名期刊的編輯委員會成員和客座編輯。陳博士與國際出版商合作出版了多本書籍，涵蓋藥物發現、草藥醫學、醫藥生物技術、奈米技術、生物工程、植物功能基因組學、植物快速育種、基於CRISPR的植物基因組編輯和人工智慧等多樣主題。他被史丹佛大學列入2023年全球前2%科學家名單。
