Difficult to Treat Asthma: Clinical Essentials
暫譯: 難治性哮喘:臨床要點

Khurana, Sandhya, Holguin, Fernando

  • 出版商: Humana Press
  • 出版日期: 2020-09-25
  • 售價: $3,980
  • 貴賓價: 9.5$3,781
  • 語言: 英文
  • 頁數: 334
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3030208141
  • ISBN-13: 9783030208141
  • 無法訂購

商品描述

This book provides a practical, stepwise, evidence-based approach to effective management of patients with difficult to treat asthma. The impact of asthma on morbidity and healthcare utilization increases exponentially with severity. Severe refractory asthma accounts for less than 5% of all asthma. Its prevalence, however, is often overestimated as there are several other confounding factors that make asthma 'difficult to treat'. Many novel (albeit expensive) therapies are now available and providers caring for patients with severe asthma are charged with selecting the best evidence treatment. This calls for complex and nuanced decision-making. Whether people with asthma gain and maintain control over their condition depends not only on the availability of effective drugs, but also multiple patient and healthcare provider behaviors. Therefore, now more than ever, it has become increasingly important to differentiate "difficult" from "severe refractory" asthma to allow identification of patients most likely to benefit from these therapies. This volume delves into the current understanding of mechanisms and increasingly recognized heterogeneity of this complex disease. It discusses a structured approach to identification and optimization of factors contributing to poor asthma control, including nonadherence, comorbidities and occupational/environmental triggers. The book includes 'state of the art' reviews on recent advances in traditional and targeted asthma therapies, as well as a glimpse into what the future may hold. Highlights include a comprehensive guide to management of severe asthma in children and pregnancy, as well as practical considerations to management of asthma based on different clinical phenotypes. Each chapter is authored by leading experts in the field who share their own clinical approach. This is an ideal guide for clinical pulmonologists and allergist/immunologists, as well as primary care providers, physician extenders in specialty practice, physicians in pulmonary/allergy training, and even industry partners.

商品描述(中文翻譯)

本書提供了一種實用的、逐步的、基於證據的方法,以有效管理難以治療的哮喘患者。哮喘對發病率和醫療利用的影響隨著病情的嚴重程度呈指數增長。重度難治性哮喘佔所有哮喘病例的比例不到5%。然而,由於存在多種其他混淆因素,使得哮喘被認為是「難以治療」的,因此其流行率往往被高估。現在有許多新型(儘管昂貴)療法可供使用,照顧重度哮喘患者的醫療提供者需要選擇最佳的證據治療方案。這需要複雜且細緻的決策過程。哮喘患者是否能夠獲得並維持對其病情的控制,不僅取決於有效藥物的可用性,還取決於多種患者和醫療提供者的行為。因此,現在比以往任何時候都更重要的是區分「難治性」與「重度難治性」哮喘,以便識別最有可能從這些療法中受益的患者。本書深入探討了對這種複雜疾病的機制及日益被認識的異質性的當前理解。它討論了一種結構化的方法,以識別和優化導致哮喘控制不良的因素,包括不依從性、合併症以及職業/環境觸發因素。本書包括對傳統和靶向哮喘療法最近進展的「最新技術」評論,以及對未來可能發展的展望。重點包括針對兒童和妊娠期重度哮喘管理的綜合指南,以及根據不同臨床表型進行哮喘管理的實用考量。每一章均由該領域的領先專家撰寫,他們分享自己的臨床方法。這是臨床肺科醫生和過敏免疫科醫生,以及初級護理提供者、專科實踐中的醫生助理、肺科/過敏訓練中的醫生,甚至是產業夥伴的理想指南。

作者簡介

Sandhya Khurana, MD is an Associate Professor of Medicine at the University of Rochester and the Co-Director of Mary Parkes Center for Asthma, Allergy & Pulmonary Care. Dr. Khurana is an adult pulmonologist with a specialized focus in management of severe and difficult to treat asthma. She is the immediate past chair of the Airways Disorders NetWork of the American College of Chest Physicians. Dr. Khurana has chaired asthma-focused sessions and participated as faculty at national and international meetings. She also serves on the American Thoracic Society and European Respiratory Society joint taskforce on severe asthma.

Fernando Holguin, MD., MPH., is Professor of Medicine and Pediatrics and the Director of the Asthma Clinical and Research Programs at the University of Colorado. Dr Holguin has been involved in asthma clinical and translational research for over 20 years. His research work primarily focuses on the intersection of obesity and asthma. Dr. Holguin co-chairs the American Thoracic Society and European Respiratory Society taskforce on Severe Asthma.

作者簡介(中文翻譯)

桑迪亞·庫拉納醫學博士(Sandhya Khurana, MD)是羅徹斯特大學(University of Rochester)內科的副教授,並擔任瑪麗·帕克斯哮喘、過敏與肺部護理中心的共同主任。庫拉納醫生是一位成人肺科醫生,專注於嚴重及難以治療的哮喘管理。她是美國胸科醫師學會(American College of Chest Physicians)氣道疾病網絡的前任主席。庫拉納醫生曾主持以哮喘為主題的會議,並在國內外會議中擔任講師。她還參與美國胸科學會(American Thoracic Society)和歐洲呼吸學會(European Respiratory Society)聯合工作小組,專注於嚴重哮喘的研究。

費爾南多·霍爾金醫學博士(Fernando Holguin, MD., MPH.)是科羅拉多大學(University of Colorado)內科和小兒科的教授,並擔任哮喘臨床與研究計劃的主任。霍爾金醫生在哮喘臨床和轉化研究方面已有超過20年的經驗。他的研究主要集中在肥胖與哮喘的交集上。霍爾金醫生共同主持美國胸科學會和歐洲呼吸學會的嚴重哮喘工作小組。