Atlas of Lymphoscintigraphy and Sentinel Node Mapping: A Pictorial Case-Based Approach
暫譯: 淋巴掃描與哨兵淋巴結定位圖譜:案例導向的圖解方法
Mariani, Giuliano, Vidal-Sicart, Sergi, Valdés Olmos, Renato A.
商品描述
The main goal of the second edition of this book is to update the content on the rapidly growing field of lymphoscintigraphy, a radionuclide-based imaging procedure that provides information on the functional status of the lymphatic system. Although the technique was originally introduced to identify the cause of peripheral edema (i.e., blockage of the venous or lymphatic circulation), more recent and widespread applications include radioguided biopsy of the sentinel lymph node in patients with solid cancers. This procedure is crucial for the adequate planning of oncologic surgery in a growing number of cancers, most notably breast cancer, cutaneous melanoma, head and neck cancers, penile cancer, and cervical cancer.
The book focuses on the latest advances in lymphoscintigraphy techniques, including both novel tracers recently approved for clinical use (especially in the field of sentinel lymph node mapping) and the expanding role of hybrid imaging with SPECT/CT - and in sentinel node detection using hybrid tracers (radiolabeled and fluorescent) for dual-signature guidance. Each chapter addresses the clinical application of lymphoscintigraphy in different anatomic areas or disease conditions. After an introductory section concerning the pathophysiology of the specific site/disease, the clinical relevance and impact of lymphoscintigraphy is demonstrated by a collection of richly illustrated teaching cases describing the lymphoscintigraphic patterns most commonly observed, as well as anatomic variants and technical pitfalls. Emphasis is placed on tomographic multimodality imaging.
The book gathers contributions by experts in nuclear oncology, who have revised their chapters by updating the didactic material and adding clinical cases. Regarding sentinel lymph node biopsy in particular, a major distinction of this text is the incorporation of the staging guidelines of the American Joint Committee on Cancer (8th edition) into the didactic material.
商品描述(中文翻譯)
本書第二版的主要目標是更新有關淋巴顯像(lymphoscintigraphy)這一快速發展領域的內容,這是一種基於放射性核素的影像程序,提供有關淋巴系統功能狀態的信息。雖然該技術最初是為了識別周邊水腫的原因(即靜脈或淋巴循環的阻塞),但最近更廣泛的應用包括對固體癌症患者的哨兵淋巴結進行放射引導活檢。這一程序對於越來越多癌症的腫瘤外科手術的充分規劃至關重要,尤其是乳腺癌、皮膚黑色素瘤、頭頸癌、陰莖癌和宮頸癌。
本書專注於淋巴顯像技術的最新進展,包括最近獲得臨床使用批准的新型示蹤劑(特別是在哨兵淋巴結定位領域)以及SPECT/CT混合影像的擴展角色——以及使用混合示蹤劑(放射性標記和螢光)進行雙重標記引導的哨兵淋巴結檢測。每一章都針對不同解剖區域或疾病狀況下淋巴顯像的臨床應用。在介紹特定部位/疾病的病理生理學後,通過一系列豐富插圖的教學案例展示淋巴顯像的臨床相關性和影響,描述最常見的淋巴顯像模式,以及解剖變異和技術陷阱。重點放在斷層多模態影像上。
本書匯集了核醫學腫瘤學專家的貢獻,他們通過更新教學材料和添加臨床案例來修訂各自的章節。特別是在哨兵淋巴結活檢方面,本書的一個主要特點是將美國癌症聯合委員會(American Joint Committee on Cancer)第八版的分期指導方針納入教學材料中。
作者簡介
From 2001 to 2014, Dr. Giuliano Mariani was a Full Professor of Nuclear Medicine and Director of the Postgraduate Specialty School in Nuclear Medicine at the University of Pisa, as well as Director of the Regional Center of Nuclear Medicine at the University Hospital of Pisa (Pisa, Italy). He had previously held similar appointments at the University and the University Hospital of Genoa (Genoa, Italy), as Associate Professor of Nuclear Medicine. His academic career began at the CNR Institute of Clinical Physiology and at the University of Pisa in 1968. He was also a Visiting Scientist and Expert Consultant at the National Cancer Institute of the National Institutes of Health (NCI, NIH), Bethesda, Maryland, USA (between 1974-1978), and Visiting Professor and Lecturer of Radiology at the Harvard Medical School, Boston, Massachusetts, USA (between 1986-1990).
Dr. Mariani's interests span virtually all of the clinical applications of Nuclear Medicine, including both diagnostic and therapeutic applications, with an emphasis on the development of novel techniques for radionuclide-based diagnosis and therapy of different tumors. He has published over 320 articles in international peer-reviewed journals. In addition to serving on the Editorial Boards of the most prestigious international journals on nuclear medicine and diagnostic imaging in general, Dr. Mariani has edited or co-edited 20 books and authored or coauthored over 100 book chapters. In addition, he currently serves as an Expert Consultant to the International Atomic Energy Agency (IAEA, Vienna) for developing and implementing nuclear medicine training programs around the world.
Sergi Vidal-Sicart is a Senior Consultant and Research Coordinator at the Nuclear Medicine Department of the Hospital Clínic Barcelona (University Hospital) and Specialist Physician at the Nuclear Medicine Department of Parc de Salut Mar (University Hospital del Mar). He is involved in projects concerning radioguided intervention and sentinel node biopsy using both conventional tracers and hybrid approaches for simultaneous radioactivity/fluorescence detection and intraoperative navigation in several malignancies. He is a founding member of the International Sentinel Node Society and member of the editorial boards of the Spanish Journal of Nuclear Medicine & Molecular Imaging and BMC Cancer. He is Former President of the Task Group on Radioguided Surgery within the Spanish Society of Nuclear Medicine and Molecular Imaging. In addition, he has been a contributing expert to training initiatives organized by the International Atomic Energy Agency (IAEA) and the European Association of Nuclear Medicine (EANM).
Renato Alfredo Valdés Olmos is a former Nuclear Medicine Consultant at the Netherlands Cancer Institute-Antoni van Leeuwenhoek (NKI-AVL). Currently, he is Clinical Researcher and Senior Consultant at the Interventional Molecular Imaging laboratory and Nuclear Medicine Section of the Department of Radiology of the Leiden University Medical Center (LUMC). He has been involved in projects concerning image guided intervention and sentinel node biopsy using hybrid approaches for radioactivity/fluorescence detection and intraoperative navigation in various malignancies as well as in molecular imaging and biopsy of breast cancer resulting in more than three-hundred PubMed indexed publications and numerous PhD theses. Former member of the editorial board of the European Journal Nuclear Medicine & Molecular Imaging, he is member of the editorial board of the Spanish Journal of Nuclear Medicine & Molecular Imaging and also editor-in-chief of the Dutch Journal of Nuclear Medicine. He is a founding member of the International Sentinel Node Society and currently member of its board. Following participation as expert in training initiatives organized by the International Atomic Energy Agency (IAEA) and the European Association of Nuclear Medicine (EANM), he has been one of the initiators of the European network RADIOguide for training and research on radioguided intervention. Former training coordinator on nuclear oncology at the NKI-AVL, he has also been in charge of training for nuclear medicine residents at the LUMC. He is currently involved in the fused radiology/nuclear medicine resident training at the Onze Lieve Vrouwe Hospital, Amsterdam.
作者簡介(中文翻譯)
從2001年到2014年,Giuliano Mariani博士擔任比薩大學核醫學的全職教授及核醫學研究所的研究生專業學校主任,同時也是比薩大學醫院(意大利比薩)的區域核醫學中心主任。他之前在熱那亞大學及熱那亞大學醫院擔任核醫學的副教授。他的學術生涯始於1968年在CNR臨床生理學研究所及比薩大學。他還曾於1974年至1978年間擔任美國國立衛生研究院(NCI, NIH)國家癌症研究所的訪問科學家及專家顧問,並於1986年至1990年間擔任哈佛醫學院(美國波士頓)的放射學訪問教授及講師。
Mariani博士的研究興趣幾乎涵蓋了核醫學的所有臨床應用,包括診斷和治療應用,特別強調開發基於放射性核素的不同腫瘤診斷和治療的新技術。他在國際同行評審期刊上發表了超過320篇文章。除了擔任核醫學及診斷影像領域最具聲望的國際期刊的編輯委員會成員外,Mariani博士還編輯或共同編輯了20本書籍,並撰寫或共同撰寫了超過100章書籍。此外,他目前擔任國際原子能機構(IAEA,維也納)的專家顧問,負責在全球範圍內開發和實施核醫學培訓計劃。
Sergi Vidal-Sicart是巴塞隆納臨床醫院(大學醫院)核醫學部的高級顧問和研究協調員,並且是Mar健康公園(大學醫院)核醫學部的專科醫生。他參與有關放射導向介入和哨兵淋巴結活檢的項目,使用傳統示蹤劑和混合方法進行同時的放射性/螢光檢測及術中導航,應用於多種惡性腫瘤。他是國際哨兵淋巴結學會的創始成員,並且是《西班牙核醫學與分子影像期刊》和《BMC癌症》的編輯委員會成員。他曾擔任西班牙核醫學與分子影像學會放射導向手術工作組的主席。此外,他還是國際原子能機構(IAEA)和歐洲核醫學協會(EANM)組織的培訓計劃的貢獻專家。
Renato Alfredo Valdés Olmos是荷蘭癌症研究所-安東尼·范·李文虎克(NKI-AVL)的前核醫學顧問。目前,他是萊頓大學醫學中心(LUMC)介入分子影像實驗室和核醫學部的臨床研究員和高級顧問。他參與有關影像導向介入和哨兵淋巴結活檢的項目,使用混合方法進行放射性/螢光檢測及術中導航,應用於各種惡性腫瘤,以及乳腺癌的分子影像和活檢,發表了超過三百篇PubMed索引的出版物和多篇博士論文。他曾是《歐洲核醫學與分子影像期刊》的編輯委員會成員,目前是《西班牙核醫學與分子影像期刊》的編輯委員會成員,並且是《荷蘭核醫學期刊》的主編。他是國際哨兵淋巴結學會的創始成員,並且目前是其董事會成員。在參與IAEA和EANM組織的培訓計劃後,他成為歐洲網絡RADIOguide的發起人之一,該網絡專注於放射導向介入的培訓和研究。他曾擔任NKI-AVL的核腫瘤學培訓協調員,並負責LUMC的核醫學住院醫師培訓。目前,他參與阿姆斯特丹Onze Lieve Vrouwe醫院的融合放射學/核醫學住院醫師培訓。