Voltage-Gated Ca2+ Channels: Pharmacology, Modulation and Their Role in Human Disease
暫譯: 電壓閘控鈣離子通道:藥理學、調節及其在人類疾病中的角色

Striessnig, Jörg

  • 出版商: Springer
  • 出版日期: 2024-08-02
  • 售價: $6,750
  • 貴賓價: 9.5$6,413
  • 語言: 英文
  • 頁數: 316
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3031384393
  • ISBN-13: 9783031384394
  • 相關分類: 電機學 Electric-machinery
  • 海外代購書籍(需單獨結帳)

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商品描述

The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.

商品描述(中文翻譯)

本卷的目的是總結有關電壓閘控鈣離子通道(voltage-gated Ca2+ channels)功能、病理生理學及其調控的新發現,以及其藥理調節的新概念。來自影響孔形成及輔助亞單元和通道相互作用蛋白的鈣通道病(Ca2+ channelopathies)提供了對通道功能和調控角色的深刻見解。此外,長期以來尋求的關鍵調控途徑的分子基礎已被發現,並且對其亞型選擇性藥理調節的令人興奮的概念也隨之而來。