Activation and Detoxification Enzymes: Functions and Implications
Chen, Chang-Hwei
- 出版商: Springer
- 出版日期: 2024-04-14
- 售價: $6,190
- 貴賓價: 9.5 折 $5,881
- 語言: 英文
- 頁數: 254
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 3031552865
- ISBN-13: 9783031552861
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商品描述
This book discusses the many advances in the understanding of the functions and implications of activation and detoxification enzymes. This organized, concise overview will meet the needs of those who are initially exposed to this important subject, particularly for students and researchers in the areas of biomedical sciences, biochemistry, nutrition, pharmacology, and chemistry. The book will also be valuable to advanced researchers. The book discusses subjects associated with foreign-compound-metabolizing enzymes with emphasis on biochemical aspects, including lipophilic foreign compounds, activation and detoxification enzymes, metabolic enzyme catalytic properties, reactive metabolic intermediates, biomedical and biochemical effects, genetic polymorphisms, enzyme inducibility, enzyme modulation for health benefits, dietary-related enzyme modulators, and structural characteristics of enzyme inducers. This new edition is updated throughout and features completely new chapters on Oxidative and Electrophilic Stresses, Metabolite- Mediated Disease Conditions, and Defense Mechanism: Nrf2-ARE Pathway.
商品描述(中文翻譯)
本書討論了對活化和解毒酶的功能和影響的許多進展。這本有組織、簡明的概述將滿足那些初次接觸這一重要主題的人的需求,特別是生物醫學科學、生物化學、營養學、藥理學和化學領域的學生和研究人員。本書對高級研究人員也具有價值。本書討論了與外源化合物代謝酶相關的主題,重點放在生化方面,包括親脂性外源化合物、活化和解毒酶、代謝酶催化特性、反應性代謝中間體、生物醫學和生化效應、基因多態性、酶誘導性、為了健康益處的酶調節、與飲食相關的酶調節劑以及酶誘導劑的結構特徵。本新版全面更新,並新增了關於氧化和電子應激、代謝物介導的疾病狀態以及防禦機制:Nrf2-ARE途徑的全新章節。
作者簡介
Chang-Hwei Chen, PhD, is a biophysicist at the Institute of Health and the Environment, Professor Emeritus of Department of Biomedical Sciences at the School of Public Health, and Former Adjunct Professor of Physics at the University of Albany, Albany, New York
作者簡介(中文翻譯)
Chang-Hwei Chen博士是健康與環境研究所的生物物理學家,也是公共衛生學院生物醫學科學系的名譽教授,以及紐約州奧爾巴尼大學物理學的前兼職教授。