Studies on the Confocal Laser Microscope
暫譯: 共焦雷射顯微鏡研究

Hamed, Abdallah Mohamed

  • 出版商: Springer
  • 出版日期: 2025-03-30
  • 售價: $2,570
  • 貴賓價: 9.5$2,442
  • 語言: 英文
  • 頁數: 143
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3031872746
  • ISBN-13: 9783031872747
  • 相關分類: 光學 Optics
  • 海外代購書籍(需單獨結帳)

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商品描述

This book provides a thorough exploration of various modulated apertures and their impact on improving microscope resolution, with a focus on confocal scanning laser microscopy (CSLM). Over the course of eleven chapters, it looks at both the theoretical aspects and practical applications of different aperture shapes.

Chapters 1 and 2 review apertures with linear, quadratic, and concentric black-and-white (B/W) zones, along with linear-quadratic and polynomial designs. Additionally, apertures with Hamming, Cauchy, rectangular, and hexagonal shapes are analyzed for their potential to enhance imaging performance.

Chapter 3 presents the computation of coherent transfer functions (CTFs) for selected modulated apertures, offering insights into their influence on imaging quality. Chapter 4 focuses on confocal microscopes, exploring how these apertures affect the imaging of microscopic objects.

A theoretical study of coherent non-scanned laser microscopes (CNSM) is covered in Chapter 5. Chapter 6 addresses the computation of lateral and axial point spread functions (PSFs) in confocal imaging systems that use binary amplitude masks, while Chapter 7 investigates the effects of misalignment errors combined with wavefront aberrations in systems using linear and quadratic apertures.

In Chapter 8, diffraction intensity is calculated for a confocal microscope with a laterally displaced truncated Gaussian aperture, extending the principles of Marechal microscopy to confocal scanning microscopy. Chapters 9 and 10 examine spatial coherence in confocal optical systems, particularly in the context of quadratic and concentric B/W apertures.

The book concludes in Chapter 11 with an application of cardiac apertures in CSLM, demonstrating their use in processing cardiac images. This work serves as a valuable reference for researchers and professionals interested in advancing microscope resolution through innovative aperture design and analysis.

商品描述(中文翻譯)

本書深入探討各種調變孔徑及其對提高顯微鏡解析度的影響,特別聚焦於共焦掃描雷射顯微鏡(Confocal Scanning Laser Microscopy, CSLM)。全書共分為十一章,涵蓋不同孔徑形狀的理論面與實際應用。

第一章和第二章回顧了具有線性、二次和同心黑白(B/W)區域的孔徑,以及線性-二次和多項式設計。此外,還分析了具有哈明(Hamming)、柯西(Cauchy)、矩形和六邊形形狀的孔徑,以評估其增強成像性能的潛力。

第三章介紹了選定調變孔徑的相干傳遞函數(Coherent Transfer Functions, CTFs)的計算,提供了對其對成像質量影響的見解。第四章專注於共焦顯微鏡,探討這些孔徑如何影響微觀物體的成像。

第五章涵蓋了相干非掃描雷射顯微鏡(Coherent Non-Scanned Laser Microscopes, CNSM)的理論研究。第六章討論了在使用二進位振幅遮罩的共焦成像系統中,橫向和軸向點擴散函數(Point Spread Functions, PSFs)的計算,而第七章則研究了在使用線性和二次孔徑的系統中,錯位誤差與波前像差的結合效應。

在第八章中,計算了具有橫向位移的截斷高斯孔徑的共焦顯微鏡的衍射強度,將Marechal顯微鏡的原則擴展到共焦掃描顯微鏡。第九章和第十章檢視了共焦光學系統中的空間相干性,特別是在二次和同心B/W孔徑的背景下。

本書在第十一章以心臟孔徑在CSLM中的應用作結,展示了其在處理心臟影像中的使用。這部作品為有興趣通過創新孔徑設計和分析來提升顯微鏡解析度的研究人員和專業人士提供了寶貴的參考。

作者簡介

Abdallah Mohamed Hamed graduated from Ain Shams University with a B.Sc. in Physics in 1973, achieving an Excellent with Honors degree. Subsequently, he earned an M.Sc. in Laser Optics from the same university in 1976. In 1978, he was awarded a scholarship in France, culminating in the acquisition of a Doctor of Physics degree in 1985.

His scholarly contributions include 95 scientific publications, with 66 of these publications are indexed in Scopus, reflecting their notable impact in the field. Moreover, he actively participates in international scientific organizations and serves as Reviewer for various scientific journals such as Opt. Eng., J. Modern Opt., Opt. & Laser Tech., and Opt. Communication. Since 2011 he has been Emeritus Professor of Physics at Ain Shams University.

作者簡介(中文翻譯)

阿卜杜拉·穆罕默德·哈梅德於1973年畢業於艾因沙姆斯大學,獲得物理學學士學位,並以優異的成績榮譽畢業。隨後,他於1976年在同一所大學獲得激光光學碩士學位。1978年,他獲得法國的獎學金,最終於1985年獲得物理學博士學位。

他的學術貢獻包括95篇科學出版物,其中66篇被Scopus索引,顯示出其在該領域的顯著影響。此外,他積極參與國際科學組織,並擔任多本科學期刊的審稿人,如Opt. Eng.、J. Modern Opt.、Opt. & Laser Tech.和Opt. Communication。自2011年以來,他一直擔任艾因沙姆斯大學的名譽物理學教授。