Physiology and Pathophysiology of Oligodendroglia
暫譯: 少突膠質細胞的生理學與病理生理學

Yi, Chenju, Butt, Arthur, Verkhratsky, Alexei

  • 出版商: Springer
  • 出版日期: 2025-06-16
  • 售價: $9,740
  • 貴賓價: 9.5$9,253
  • 語言: 英文
  • 頁數: 433
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 303187918X
  • ISBN-13: 9783031879180
  • 尚未上市,無法訂購

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商品描述

This single volume provides a comprehensive description of oligodendroglia, the neural cells responsible for myelination of axons throughout the central nervous system. Myelinated axons create the white matter (connectome) of the human brain and spinal cord, which connect and synchronize hundreds of billions of neurons, thus defining the information processing function of the central nervous system. Oligodendrocytes and myelination play an essential role in regulating every bodily function and behavior. Damage to white matter, myelin, and oligodendrocytes results in severe diseases of the CNS. Pathology and Pathophysiology of Oligodendroglia, presented by the major authorities in the field, is the very first reference to combine, under a single cover, a full and detailed description of the physiology and pathophysiology of oligodendroglia, with a particular emphasis on neurodegenerative diseases.


商品描述(中文翻譯)

這本單卷書全面描述了寡突膠質細胞(oligodendroglia),這些神經細胞負責中樞神經系統中軸突的髓鞘化。髓鞘化的軸突形成了人腦和脊髓的白質(connectome),這些白質連接並同步數以千億計的神經元,從而定義了中樞神經系統的信息處理功能。寡突膠質細胞和髓鞘化在調節每一種身體功能和行為中扮演著至關重要的角色。白質、髓鞘和寡突膠質細胞的損傷會導致中樞神經系統的嚴重疾病。《寡突膠質細胞的病理學與病理生理學》(Pathology and Pathophysiology of Oligodendroglia)由該領域的主要權威人士呈現,是首部在單一書籍中綜合全面且詳細描述寡突膠質細胞的生理學和病理生理學的參考書,特別強調神經退行性疾病。

作者簡介

Chenju Yi, MD, Ph.D. is Professor of Neuroscience and Neurology at the Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China. She obtained MD and PhD from Eberhard Karls Universität Tübingen, Germany and Huazhong University of Science and Technology, China, respectively. She carried out postdoctoral research mentored by Prof. Christian Giaume at the Collège de France in Paris, followed by a Senior Research Fellowship at National University of Singapore. Her research has made groundbreaking contributions to understanding the mechanisms by which glia drive the pathophysiology of brain disorders, such as Alzheimer's disease, with a particular focus on glial connexins.

Alexei Verkhratsky, MD, Ph.D., D.Sc. is Professor of Neurophysiology in the Faculty of Biology, Medicine and Health at The University of Manchester in Manchester, England. Verkhratsky is an internationally recognized scholar in the field of cellular neurophysiology, best known for his contributions to our knowledge of the physiology and pathophysiology of neuroglia.

Jianqin Niu, Ph.D., is Professor of Neuroscience in the Third Military Medical University, Chongqing, China. Niu graduated from the Third Military Medical University and completed a postdoctoral fellowship at both the Collège de France in Paris and the University of California, San Francisco (UCSF). His research primarily investigates oligodendrocyte precursor cells (OPCs), exploring both their myelinating and non-myelinating roles within the central nervous system. His work emphasizes cellular mechanisms and pathological processes underlying neurological and psychiatric disorders, with particular focus on how OPCs interact with other glial cell populations to influence disease pathogenesis.

Arthur M. Butt, Ph.D., is Professor of Cellular Neurophysiology at the University of Portsmouth, U.K.. He obtained his PhD on the blood brain barrier in King's College London and the Marine Laboratories Plymouth. After postdoctoral research on glial cells and the blood brain barrier as a Grass Fellow at Wood's Hole Marine Laboratories and Yale University USA, Arthur obtained his first independent position at Guy's and St Thomas' Hospitals, London, and later obtained his personal chair at King's College London. He is an international expert in glial cell biology.

作者簡介(中文翻譯)

陳居怡醫學博士、哲學博士是中國深圳中山大學第七附屬醫院的神經科學與神經學教授。她分別在德國圖賓根大學和中國華中科技大學獲得醫學博士和哲學博士學位。她在法國巴黎的法國學院進行了由克里斯蒂安·吉奧梅教授指導的博士後研究,隨後在新加坡國立大學擔任高級研究員。她的研究對於理解膠質細胞如何驅動大腦疾病的病理生理學(如阿茲海默症)機制做出了開創性的貢獻,特別專注於膠質連接蛋白。

阿列克謝·維克拉茨基醫學博士、哲學博士、科學博士是英國曼徹斯特大學生物、醫學與健康學院的神經生理學教授。維克拉茨基是細胞神經生理學領域的國際知名學者,以其對神經膠質的生理學和病理生理學知識的貢獻而聞名。

牛建勤哲學博士是中國重慶第三軍醫大學的神經科學教授。牛教授畢業於第三軍醫大學,並在法國學院和加州大學舊金山分校(UCSF)完成了博士後研究。他的研究主要探討寡突膠質細胞前體(OPCs),研究其在中樞神經系統中的髓鞘形成和非髓鞘形成角色。他的工作強調神經和精神疾病的細胞機制和病理過程,特別關注OPCs如何與其他膠質細胞群體互動以影響疾病的發病機制。

亞瑟·M·巴特哲學博士是英國朴茨茅斯大學的細胞神經生理學教授。他在倫敦國王學院和普利茅斯海洋實驗室獲得了有關血腦屏障的博士學位。在伍茲霍爾海洋實驗室和美國耶魯大學作為草地研究員進行了有關膠質細胞和血腦屏障的博士後研究後,亞瑟在倫敦的蓋伊醫院和聖托馬斯醫院獲得了第一個獨立職位,並在倫敦國王學院獲得了個人講座。他是膠質細胞生物學的國際專家。

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