Immunotherapies in Solid Tumors: A Team Medicine Approach
暫譯: 實體腫瘤中的免疫療法：團隊醫療方法

本書涵蓋了最先進的免疫療法模式，並討論了癌細胞的表型可塑性在免疫抗性出現中的關鍵角色。

本書針對醫學腫瘤學家和基礎癌症研究人員，填補了一個重要的空白，強調了團隊醫學方法的重要性，該方法整合了主要醫療中心及其網絡中的臨床實踐。其目標是教育專業人士了解整合方法的重要性，以提升腫瘤學研究和病人護理的質量。本書作為一個重要資源，對於面臨整合基礎與轉譯研究以及臨床醫學的學術中心及其全球臨床網絡的社群而言，具有重要意義。

本書由該領域的世界知名專家撰寫，專注於整合基礎科學家和臨床醫生在學術中心及其臨床網絡中的經驗和專業知識，填補了文獻中的一個重要空白。

Ravi Salgia, MD, PhD

Professor and Arthur & Rosalie Kaplan Chair in Medical Oncology

City of Hope National Medical Center

Duarte, California, USA

Ravi Salgia, MD, PhD, is Chair of Medical Oncology & Therapeutics Research at City of Hope National Medical Center, in Duarte, California. Dr. Salgia also holds the Arthur and Rosalie Kaplan Chair in Medical Oncology. Previously, Dr. Salgia was Professor of Medicine, Pathology and Dermatology, and the Director of the Thoracic Oncology Program, and Aerodigestive Tract Program Translational Research at the University of Chicago. His research interests focus on novel therapeutics against lung cancer. Dr. Salgia has been honored with numerous awards, including being named one of the Top Doctors in America and awarded the Sun Pharma Distinguished Scientist Award (Clinical Sciences). Prior to his tenure at University of Chicago School of Medicine, Dr. Salgia was faculty at the Dana-Farber Cancer Institute and Harvard Medical School. He earned his undergraduate summa cum laude in mathematics, biology, and chemistry, and then his MD and PhD degrees from Loyola University in Chicago, IL, where he also completed fellowships in neurochemistry and physiology. He continued his postgraduate training with an internship and residency in internal medicine at The Johns Hopkins University School of Medicine in Baltimore, MD, followed by a fellowship in medical oncology at Dana-Farber Cancer Institute in Boston, MA, during which time he also served as a clinical fellow at Harvard Medical School in Boston.

Prakash Kulkarni, Ph.D., is Research Professor and Director of Translational Research in the Department of Medical Oncology and has a courtesy appointment in the Department of Systems Biology at the City of Hope National Medical Centre in Duarte, California. After receiving his PhD in biochemistry from India, he did postdoctoral training in biochemistry at the Indian Institute of Science and in cell biology at the New York University School of Medicine. He was an Assistant Professor at Johns Hopkins University School of Medicine where he was named the Irene and Bernard L. Schwartz Scholar of the Patrick Walsh Fund. He then moved to the W. M. Keck Laboratory for Structural Biology, University of Maryland Institute for Bioscience and Biotechnology Research, as a Research Associate Professor. Prior to joining Johns Hopkins, Prof. Kulkarni held Staff Scientist positions in the Division of Chemistry & Chemical Engineering, the Division of Biology at Caltech, and in the Department of Genetics at Yale University School of Medicine. His research interests are interdisciplinary and are focused on understanding at a system level how conformational dynamics of intrinsically disordered proteins and noise contribute to phenotypic switching, especially in cancer and evolution. Prof. Kulkarni was a Visiting Professor in the Department of Mathematics, and the Department of Bioengineering at the Indian Institute of Science and is currently a Visiting Professor in the Division of Biology and Biological Engineering at Caltech. He is a Fellow of the Royal Society of Biology, UK, and inducted Member, Sigma Xi, The Scientific Research Honor Society.

Ravi Salgia, MD, PhD
醫學腫瘤學教授及亞瑟與羅莎莉·卡普蘭醫學腫瘤學講座教授
希望之城國家醫療中心
美國加州杜阿特

Ravi Salgia, MD, PhD，現任希望之城國家醫療中心醫學腫瘤學與治療研究主任，位於加州杜阿特。Salgia醫生同時擔任亞瑟與羅莎莉·卡普蘭醫學腫瘤學講座教授。之前，Salgia醫生曾擔任芝加哥大學的內科、病理學和皮膚科教授，以及胸腔腫瘤計畫和氣道消化道計畫的轉譯研究主任。他的研究興趣集中在針對肺癌的新型治療方法。Salgia醫生曾獲得多項榮譽，包括被評選為美國頂尖醫生之一，以及獲得陽光製藥傑出科學家獎（臨床科學）。在芝加哥大學醫學院任職之前，Salgia醫生曾在達納法伯癌症研究所和哈佛醫學院任教。他在數學、生物學和化學方面以優異成績獲得學士學位，隨後在伊利諾伊州的洛約拉大學獲得醫學博士和博士學位，並在該校完成神經化學和生理學的研究員訓練。他在馬里蘭州巴爾的摩的約翰霍普金斯大學醫學院進行內科實習和住院醫師訓練，之後在麻薩諸塞州波士頓的達納法伯癌症研究所進行醫學腫瘤學的研究員訓練，期間也在波士頓的哈佛醫學院擔任臨床研究員。

Prakash Kulkarni, Ph.D.
研究教授及醫學腫瘤學部門轉譯研究主任
希望之城國家醫療中心
美國加州杜阿特

Prakash Kulkarni, Ph.D.，是希望之城國家醫療中心醫學腫瘤學部門的研究教授及轉譯研究主任，並在系統生物學部門擔任兼任職位。Kulkarni博士在印度獲得生物化學博士學位後，於印度科學研究所進行生物化學的博士後訓練，並在紐約大學醫學院進行細胞生物學的博士後訓練。他曾在約翰霍普金斯大學醫學院擔任助理教授，並被評選為帕特里克·沃爾什基金的艾琳和伯納德·L·施瓦茨學者。隨後，他轉至馬里蘭大學生物科學與生物技術研究所的W. M. Keck結構生物學實驗室擔任研究副教授。在加入約翰霍普金斯之前，Kulkarni教授曾在加州理工學院的化學與化學工程部門、加州理工學院的生物學部門以及耶魯大學醫學院的遺傳學部門擔任科學家職位。他的研究興趣跨學科，專注於從系統層面理解內在無序蛋白質的構象動力學和噪音如何影響表型轉換，特別是在癌症和進化方面。Kulkarni教授曾在印度科學研究所的數學系和生物工程系擔任訪問教授，目前是加州理工學院生物學與生物工程部門的訪問教授。他是英國皇家生物學會的會員，並是Sigma Xi科學研究榮譽學會的入會成員。