Salivary Gland Development and Regeneration: Advances in Research and Clinical Approaches to Functional Restoration
暫譯: 唾液腺發展與再生：研究與臨床方法在功能恢復上的進展

Seunghee Cha, DDS, PhD, is a Professor of Oral & Maxillofacial Diagnostic Sciences at the University of Florida College of Dentistry. Dr. Cha is actively involved in basic and clinical science research while attending patients and serving in leadership roles for various international scientific communities. She was the former President of the Salivary Research Group of the American/International Association for Dental Research and currently oversees research and patient care as the Director of the Center for Orphaned Autoimmune Disorders. Dr. Cha's research focuses on the pathogenesis of autoimmune Sjӧgren's disease (SS-> SjD) and cell replacement therapy to improve dry mouth in SS ->SjD patients. In particular, she has investigated the pathological roles of anti-muscarinic type 3 receptor autoantibodies in hyposalivation, epigenetic regulation of microRNA and its functions in innate immunity, self-nucleic acid sensing mechanisms in monocytes, susceptibility genes by high-throughput genomics and proteomics, and diagnostic and therapeutic strategies for SS-> SjD. Dr. Cha has published extensively in peer-reviewed international journals.

車承熙，牙醫學博士，哲學博士，是佛羅里達大學牙醫學院口腔與顎面診斷科的教授。車博士積極參與基礎與臨床科學研究，同時照顧病人並在各種國際科學社群中擔任領導角色。她曾擔任美國/國際牙科研究協會唾液研究小組的主席，目前擔任孤兒自體免疫疾病中心的主任，負責研究和病人護理。車博士的研究專注於自體免疫性乾燥症（SS -> SjD）的發病機制以及細胞替代療法，以改善SS -> SjD病人的口乾症。特別是，她研究了抗毒蕈鹼型3受體自體抗體在唾液減少中的病理角色、微小RNA的表觀遺傳調控及其在先天免疫中的功能、單核細胞中的自我核酸感知機制、高通量基因組學和蛋白質組學的易感基因，以及針對SS -> SjD的診斷和治療策略。車博士在同行評審的國際期刊上發表了大量研究成果。