Single-Molecule Super-Resolution Optical Microscopy
暫譯: 單分子超解析光學顯微鏡技術
Mondal, Partha Pratim, Hess, Samuel
相關主題
商品描述
This book provides a comprehensive introduction to the field of single-molecular super-resolution microscopy. It covers the behavior of light as it propagates through optical elements and specially designed optical systems, the wave nature of light and its interaction with single molecules, the photophysics of single molecules, the instrumentation and dedicated single-photon detectors necessary for single-molecule detection, and the future of quantum aspects of light in super-resolution microscopy.
With its gradual progression from the basics of light to the most advanced techniques in single-molecule-based super-resolution microscopy, this book's easy-to-understand language and focus on the interdisciplinary nature of single-molecule science make it ideal for students from a wide range of research disciplines across physics, chemistry, biology, medicine, and engineering. Written in a way that is accessible to everyone, from undergraduates to experts, this book does not require a strong background in physics or optics and deliberately avoids the use of extreme mathematics in favor of logical arguments and simple reasoning to explain complex concepts. Chapter-end questions and worked examples round out this entirely self-contained textbook, making it the ideal accompaniment to courses on imaging optics and single-molecule science.
商品描述(中文翻譯)
這本書提供了單分子超解析顯微鏡領域的全面介紹。內容涵蓋了光在光學元件和專門設計的光學系統中傳播的行為、光的波動性質及其與單分子的相互作用、單分子的光物理學、單分子檢測所需的儀器和專用單光子探測器，以及光在超解析顯微鏡中量子特性的未來。
本書從光的基本概念逐步進入單分子超解析顯微鏡中最先進的技術，使用易於理解的語言，並專注於單分子科學的跨學科特性，使其成為來自物理、化學、生物、醫學和工程等多個研究領域的學生的理想選擇。這本書的寫作方式使其對所有人都易於接觸，無論是本科生還是專家，並不需要強大的物理或光學背景，故意避免使用極端的數學，而是通過邏輯論證和簡單推理來解釋複雜概念。章末問題和實例分析使這本完全自足的教科書更加完善，成為影像光學和單分子科學課程的理想輔助教材。
作者簡介
Partha P. Mondal was born in Hanskhali, West Bengal, India, on February 21, 1978, received his Ph.D. in physics in 2006 from the Indian Institute of Science, Bangalore, India. He was Researcher at the Massachusetts Institute of Technology (USA), International Center for Theoretical Physics (Italy), and University of Genova (Italy). Subsequently, he joined the Indian Institute of Science as Assistant Professor in 2010 and currently serves as Full Professor and Chairman of Centre for Cryogenic Technology. He is credited with the invention of iLIFE lightsheet imaging cytometry, iCLASS lightsheet nanolithography and Lightsheet Optical Tweezer (LOT). He visited several universities as visiting Professor and has served on the editorial board of several journals. He authored three books: classical & quantum optics, light sheet microscopy & imaging, and fundamentals of fluorescence microscopy. His laboratory (Nanobioimaging Lab) specializes in optical tweezer, imaging cytometry, optical instrumentation, fluorescence spectroscopy, super-resolution microscopy, nanobiology, fluorescence imaging, cell & disease biophysics and single molecule physics.
Samuel T. Hess developed fluorescence photoactivation localization microscopy (FPALM), one of three new techniques to break the diffraction barrier in 2006, offering life scientists an incredible boost in imaging power. He is a professor of physics in the Department of Physics and Astronomy at the University of Maine, Orono, Maine. Prof. Hess earned all of his degrees in physics: his B.S. at Yale and M.S. and Ph.D. at Cornell University.
作者簡介(中文翻譯)
Partha P. Mondal 於1978年2月21日出生於印度西孟加拉邦的 Hanskhali，並於2006年在印度班加羅爾的印度科學研究所獲得物理學博士學位。他曾在美國麻省理工學院、意大利國際理論物理中心及意大利熱那亞大學擔任研究員。隨後，他於2010年加入印度科學研究所擔任助理教授，目前擔任冷凍技術中心的正教授及主任。他因發明 iLIFE 燈片成像細胞計數技術、iCLASS 燈片納米光刻技術及燈片光學鉗 (LOT) 而受到讚譽。他曾作為訪問教授造訪多所大學，並在多本期刊的編輯委員會中任職。他著有三本書籍：經典與量子光學、燈片顯微鏡與成像，以及螢光顯微鏡的基本原理。他的實驗室 (Nanobioimaging Lab) 專注於光學鉗、成像細胞計數、光學儀器、螢光光譜學、超解析顯微鏡、納米生物學、螢光成像、細胞與疾病生物物理學及單分子物理學。
Samuel T. Hess 開發了螢光光激活定位顯微鏡 (FPALM)，這是2006年三種突破衍射極限的新技術之一，為生命科學家提供了驚人的成像能力提升。他是美國緬因州奧羅諾的緬因大學物理與天文系的物理學教授。Hess 教授在物理學領域獲得了所有學位：在耶魯大學獲得學士學位，並在康奈爾大學獲得碩士及博士學位。
