Cancer Metabolism: Molecular Mechanisms and Therapeutic Strategies
暫譯: 癌症代謝:分子機制與治療策略

Ashique, Sumel, Taghizadeh-Hesary, Farzad, Debnath, Biplab

  • 出版商: Springer
  • 出版日期: 2026-05-19
  • 售價: $6,000
  • 貴賓價: 9.5 折 $5,700
  • 語言: 英文
  • 頁數: 275
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 3032218608
  • ISBN-13: 9783032218605
  • 相關分類: 理工類
  • 海外代購書籍(需單獨結帳)

相關主題

商品描述

Cancer cells survive and thrive by radically reshaping the way they use energy, nutrients, and metabolic pathways. This book offers a clear and comprehensive exploration of this rapidly evolving field, revealing how tumors rewire core biochemical processes to sustain proliferation, evade cell death, and adapt to the pressures of the tumor microenvironment. From foundational concepts to cutting-edge discoveries, the book provides an essential entry point for understanding the metabolic logic that underlies cancer progression.

Central to this volume is an in-depth examination of glutamine metabolism. Alongside this focus, the book extends broadly across the metabolic landscape, covering glycolysis, lipid synthesis and utilization, redox regulation, mitochondrial dynamics, and metabolic communication between cancer cells and their surrounding stromal and immune partners. Each chapter distills mechanistic insight while emphasizing translational relevance, bridging basic science with the latest therapeutic strategies and clinical applications.

Written by leading researchers and clinicians, this book serves as a valuable resource for scientists, oncologists, and drug developers seeking to understand and target the metabolic vulnerabilities of cancer. Whether exploring metabolic reprogramming in cancer stem cells, evaluating biomarkers of metabolic states, or assessing emerging therapies and clinical trial data, readers will gain an integrated perspective on how metabolism shapes tumor behavior and influences treatment outcomes. This is an indispensable guide for anyone committed to advancing cancer research, improving patient care, and translating metabolic insights into meaningful therapeutic advances.

商品描述(中文翻譯)

癌細胞透過徹底重塑其能量、營養和代謝途徑的使用方式來生存和繁衍。本書提供了對這一快速發展領域的清晰且全面的探索,揭示腫瘤如何重新連接核心生化過程,以維持增殖、逃避細胞死亡並適應腫瘤微環境的壓力。從基礎概念到前沿發現,本書為理解癌症進展背後的代謝邏輯提供了重要的入門點。

本書的核心是對谷氨酰胺代謝的深入探討。除了這一重點外,本書還廣泛涵蓋了代謝領域,包括糖解作用、脂質合成與利用、氧化還原調控、線粒體動態以及癌細胞與其周圍基質和免疫夥伴之間的代謝通信。每一章都提煉出機制性見解,同時強調轉化相關性,橋接基礎科學與最新的治療策略和臨床應用。

本書由領先的研究人員和臨床醫生撰寫,是科學家、腫瘤學家和藥物開發者了解和針對癌症代謝脆弱性的寶貴資源。無論是探索癌症幹細胞中的代謝重編程、評估代謝狀態的生物標記,還是評估新興療法和臨床試驗數據,讀者將獲得一個整合的視角,了解代謝如何塑造腫瘤行為並影響治療結果。這是一本對於致力於推進癌症研究、改善病人護理以及將代謝見解轉化為有意義的治療進展的人士來說不可或缺的指南。

作者簡介

Sumel Ashique

Pharmaceutical Technology, Bharat Technology
Howrah, West Bengal, India

Farzad Taghizadeh-Hesary

Assistant Professor,

Breast Cancer Research Center, Iran University of Medical Sciences

Iran University of Medical Sciences

Tehran, Iran

Biplab Debnath

Professor & Principal

Bharat Technology

Uluberia

West Bengal, India

Ayush Madan, B.Tech., M.Tech., DBT-JRF, Ph.D. (p)

Assistant Professor,

Department of Biotechnology,

School of Research & Technology,

People's University, Bhanpur, Bhopal.

Former Graduate Research Assistant,

Institute of Tropical Aquaculture and Fisheries,

Universiti Malaysia Terengganu,

21030 Kuala Nerus, Terengganu, Malaysia

作者簡介(中文翻譯)

Sumel Ashique
製藥科技,巴拉特科技
印度西孟加拉邦霍拉

Farzad Taghizadeh-Hesary
助理教授
乳腺癌研究中心,伊朗醫科大學
伊朗醫科大學
伊朗德黑蘭

Biplab Debnath
教授及校長
巴拉特科技
烏魯貝里亞
印度西孟加拉邦

Ayush Madan, B.Tech., M.Tech., DBT-JRF, Ph.D. (p)
助理教授
生物技術系
研究與技術學院
人民大學,班普爾,博帕爾
前研究生助理
熱帶水產養殖與漁業研究所
馬來西亞登嘉樓大學
21030 登嘉樓,馬來西亞