Extracellular Matrix Biomimicking for Theranostics
暫譯: 細胞外基質仿生技術於治療診斷中的應用

Suhag, Deepa

  • 出版商: Springer
  • 出版日期: 2026-05-25
  • 售價: $8,190
  • 貴賓價: 9.5$7,780
  • 語言: 英文
  • 頁數: 342
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 981957899X
  • ISBN-13: 9789819578993
  • 相關分類: 材料科學 Meterials
  • 海外代購書籍(需單獨結帳)

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商品描述

This book explores the rapidly advancing intersection of biomaterials science and clinical diagnostics and therapeutics, collectively known as Theranostics. It focuses on the design, development, and translational application of extracellular matrix (ECM)-mimicking biomaterials as next-generation platforms for improving diagnostic accuracy, therapeutic delivery, and treatment predictability--particularly in cancer, tissue regeneration, and personalized medicine.

At its core, the book examines how biomimetic ECM systems replicate the structural, biochemical, and mechanical cues of native tissues, enabling more physiologically relevant in vitro and in vivo environments. By emulating the dynamic and hierarchical architecture of the ECM, these materials demonstrate significant potential in enhancing drug delivery, predicting therapeutic efficacy, and facilitating tissue repair and regeneration.

The book provides in-depth coverage of advanced fabrication strategies, including 3D bioprinting, molecular self-assembly, and decellularization-based approaches, for creating functional ECM analogs. Each chapter presents case studies, experimental findings, and applied methodologies, illustrating how ECM biomimicry is being integrated into theranostic systems across diverse biomedical applications. A distinguishing feature of this volume is its incorporation of high-quality illustrations, 3D renderings, and comprehensive tables, which visually elucidate complex mechanisms, material architectures, and data interpretation.

This book offers a holistic framework for leveraging ECM biomimicking in Theranostics by bridging fundamental biomaterials research with applied clinical translation. It serves as a valuable resource for biomaterials scientists, bioengineers, clinicians, and translational researchers seeking to stay at the forefront of regenerative medicine, cancer therapy, and diagnostic innovation.

商品描述(中文翻譯)

這本書探討了生物材料科學與臨床診斷和治療之間快速發展的交集,統稱為治療診斷學(Theranostics)。它專注於設計、開發和轉譯應用模仿細胞外基質(extracellular matrix, ECM)的生物材料,作為改善診斷準確性、治療傳遞和治療預測性的下一代平台,特別是在癌症、組織再生和個人化醫療方面。

本書的核心在於檢視生物模擬ECM系統如何複製天然組織的結構、生化和機械信號,從而實現更具生理相關性的體外和體內環境。通過模仿ECM的動態和分層結構,這些材料在增強藥物傳遞、預測治療效果以及促進組織修復和再生方面顯示出顯著潛力。

本書深入探討了先進的製造策略,包括3D生物列印、分子自組裝和去細胞化方法,以創建功能性ECM類似物。每一章節都呈現案例研究、實驗結果和應用方法,說明ECM生物模擬如何被整合到各種生物醫學應用的治療診斷系統中。本書的一個顯著特點是其包含高品質的插圖、3D渲染和綜合表格,這些視覺資料清晰闡明了複雜的機制、材料結構和數據解釋。

這本書提供了一個整體框架,通過將基礎生物材料研究與應用臨床轉譯相結合,來利用ECM生物模擬於治療診斷學中。它是生物材料科學家、生物工程師、臨床醫生和轉譯研究人員的寶貴資源,幫助他們在再生醫學、癌症治療和診斷創新方面保持領先地位。

作者簡介

Dr. Deepa Suhag is an Assistant Professor at the Amity School of Applied Sciences, Amity University Haryana, India. She has authored several peer-reviewed research articles published in leading international journals and has filed six patents, including two granted patents by the Government of India, as of now. One of her granted patents, titled "Method for preparation of highly fluorescent biocompatible sulphur-doped graphene quantum dots from affordable agro-industrial bio-waste cane molasses using hydrothermal synthesis for bioimaging applications," was awarded on 19 May 2022. Dr. Suhag has also authored research monographs and edited scholarly books. She is also the recipient of competitive research funding from prestigious Indian government agencies, including DRDO and ICMR, supporting her work in advanced biomaterials and regenerative medicine. Her research interests include biomaterials engineering, wound healing, and tissue regeneration, with a strong focus on developing translational, clinically relevant biomimetic materials.

作者簡介(中文翻譯)

深帕·蘇哈格博士是印度哈里亞納邦阿米提大學應用科學學院的助理教授。她已發表多篇經過同行評審的研究文章,這些文章刊登於領先的國際期刊,並且目前已申請六項專利,其中包括兩項由印度政府授予的專利。她的一項授予專利的標題為「從可負擔的農業工業生物廢料甘蔗糖蜜中使用水熱合成法製備高螢光生物相容性硫摻雜石墨烯量子點的方法,用於生物成像應用」,該專利於2022年5月19日獲得授權。蘇哈格博士還撰寫了研究專著並編輯了學術書籍。她也是來自印度政府機構(包括DRDO和ICMR)競爭性研究資助的獲得者,支持她在先進生物材料和再生醫學方面的研究工作。她的研究興趣包括生物材料工程、傷口癒合和組織再生,並強調開發轉化性、臨床相關的仿生材料。