商品描述
The book offers a timely and comprehensive overview of how oxidative stress influences chronic disease onset, progression, and management. A balanced view of antioxidants and their protective and potentially harmful effects is presented in this book, which combines cutting-edge biochemical research with practical health applications. A review of mechanisms that regulate cellular health, immune function, and disease resistance is presented in this book. The book focuses on key antioxidative enzymes and redox biology. The book covers topics such as the interactions between reactive oxygen, nitrogen, and sulfur species, as well as the therapeutic use of natural antioxidants. There will be valuable insights to be gained by readers into: (i) The role that oxidative stress plays in the development of chronic diseases like cardiovascular disorders, neurodegenerative disorders, and metabolic syndromes. (ii) In terms of their molecular mechanism and biological impact, antioxidants and prooxidants play important roles. (iii) In the fields of food, cosmetics, and medicine, natural product pharmacology, antioxidant delivery systems, and redox-active formulations are of particular interest. For these reasons, the book starts by pointing out that chronic diseases are becoming a global burden and that a deeper understanding of their molecular basis is urgently needed. A key goal of this book is to bridge the gap between fundamental research and clinical applications by providing an overview of recent advances in mechanisms, biomarkers, and therapeutic strategies for oxidative stress. A valuable resource for biotechnologists, biochemists, biomedical sciences and healthcare professionals working in biochemistry, pharmacology, nutrition and natural product chemistry and doctoral students who wish to understand and address the complex interactions between oxidative stress and chronic diseases, this book can be of great assistance to them.
商品描述(中文翻譯)
本書提供了一個及時且全面的概述，說明氧化壓力如何影響慢性疾病的發生、進展和管理。本書以平衡的視角探討抗氧化劑及其保護和潛在有害的效果，結合了前沿的生化研究與實用的健康應用。書中回顧了調節細胞健康、免疫功能和疾病抵抗的機制。本書專注於關鍵的抗氧化酶和氧化還原生物學，涵蓋了反應性氧、氮和硫物種之間的相互作用，以及天然抗氧化劑的治療用途。讀者將能獲得寶貴的見解，包括：(i) 氧化壓力在心血管疾病、神經退行性疾病和代謝綜合症等慢性疾病發展中的角色。(ii) 抗氧化劑和促氧化劑在其分子機制和生物影響方面扮演的重要角色。(iii) 在食品、化妝品和醫學領域，自然產品藥理學、抗氧化劑傳遞系統和氧化還原活性配方特別受到關注。
基於這些原因，本書首先指出慢性疾病正成為全球負擔，迫切需要對其分子基礎有更深入的了解。本書的一個主要目標是通過提供氧化壓力機制、標誌物和治療策略的最新進展概述，來彌補基礎研究與臨床應用之間的鴻溝。本書對於生物技術學家、生化學家、生物醫學科學和醫療專業人員，特別是在生化學、藥理學、營養學和天然產品化學領域工作的博士生，都是一個寶貴的資源，幫助他們理解和應對氧化壓力與慢性疾病之間的複雜相互作用。
作者簡介
Dr. Azhaguchamy Muthukumaran is a Professor in the Department of Biotechnology at Kalasalingam Academy of Krishnankoil, India. With over 16 years of experience teaching undergraduate and postgraduate biotechnology courses, he has made significant academic and research contributions. His primary research interests are cardiac tissue engineering, nanotoxicology, and the antioxidative applications of selenium nanoparticles. Dr. Muthukumaran has successfully led research grants funded by various national agencies to develop selenium-based biomaterials for cardiac tissue regeneration. His work is distinguished by its translational value and its emphasis on the protective and regenerative properties of nanomaterials. Dr. Muthukumaran has supervised numerous doctoral scholars in the field of selenium-based materials for cardiac applications and has established strong collaborative research partnerships with national and international institutions. His academic leadership is evident through his roles, which have played a key role in global academic quality assurance. He has served as Programme Chair for the Accreditation Board for Engineering and Technology (ABET) for the Biotechnology programme at Kalasalingam Academy of Research and Education. Dr. Muthukumaran continues to make significant contributions to the advancement of biotechnology through his interdisciplinary research, academic leadership, and dedication to training the next generation of scientists. Kasinathan Kaviyarasu is a researcher at the University of South Africa (UNISA) under the UNESCO Africa Chair in Nanosciences/Nanotechnology category. He is a emerging researcher who has made significant contributions to biomedical applications through his research in nanoscience and nanotechnology. Functional materials for bio-catalysis, tissue engineering, and hierarchical nanostructures for bio-interfaces are the focus of his research. Intriguingly, Dr. Kasinathan Kaviyarasu has contributed to several textbooks published by Springer, focusing on nanomaterials, energy conversion, biomedical applications, and environmental sustainability.
作者簡介(中文翻譯)
阿扎古查米·穆圖庫馬蘭博士是印度克里希南科伊爾的卡拉薩林甘學院生物技術系教授。他在本科和研究生生物技術課程的教學上擁有超過16年的經驗，並在學術和研究方面做出了重要貢獻。他的主要研究興趣包括心臟組織工程、奈米毒理學以及硒奈米顆粒的抗氧化應用。穆圖庫馬蘭博士成功主導了由多個國家機構資助的研究計畫，旨在開發基於硒的生物材料以促進心臟組織再生。他的工作以其轉化價值和對奈米材料保護性及再生特性的強調而著稱。穆圖庫馬蘭博士在基於硒的心臟應用材料領域指導了眾多博士生，並與國內外機構建立了強有力的合作研究夥伴關係。他的學術領導力在其角色中得以體現，這些角色在全球學術質量保證中發揮了關鍵作用。他曾擔任卡拉薩林甘研究與教育學院生物技術課程的工程與技術認證委員會（ABET）項目主席。穆圖庫馬蘭博士通過其跨學科研究、學術領導力以及對培養下一代科學家的奉獻，持續為生物技術的發展做出重要貢獻。
卡西納坦·卡維亞拉蘇是南非大學（UNISA）在聯合國教科文組織非洲奈米科學/奈米技術類別下的研究員。他是一位新興研究者，通過在奈米科學和奈米技術方面的研究對生物醫學應用做出了重要貢獻。他的研究重點是用於生物催化、組織工程的功能材料以及用於生物介面的分層奈米結構。有趣的是，卡西納坦·卡維亞拉蘇博士為施普林格出版的幾本教科書做出了貢獻，這些書籍專注於奈米材料、能源轉換、生物醫學應用和環境可持續性。
