New Biology for Engineers and Computer Scientists
暫譯: 工程師與計算機科學家的新生物學

Aydin Tozeren, Stephen W. Byers

New Biology for Engineers and Computer Scientists
  • 出版商: Prentice Hall
  • 出版日期: 2003-05-09
  • 售價: $850
  • 貴賓價: 9.8 折 $833
  • 語言: 英文
  • 頁數: 304
  • 裝訂: Paperback
  • ISBN: 0130664634
  • ISBN-13: 9780130664631
  • 相關分類: 生物資訊 Bioinformatics

    • 下單後立即進貨 (約5~7天)

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商品描述

 

For biology courses in engineering and computer science departments.

Taking a system approach to expose modern biology, this book presents the fundamental system principles and parameters common to all living species. The straightforward examination begins with a presentation of molecular cell biology and progresses to the complex interrelationship between genes and proteins as observed in metabolic process, signal transduction, cell division and embryonic development. The text's unique approach provides a depiction of the human genome project, a review of high throughput biology and bioinformatic tools and a presentation of gene circuitry and pathway analysis as applied to cell division, development of embryo and metabolic pathways and expose of emerging proteomic science.

Table of Contents：

1. The Chemistry of Life.

Atoms. Molecules and Covalent Bonds. Ionic Compounds and Electrostatic Bonds. Water and Hydrogen Bonds. Lipids and Van der Waals Attratction. Acids and Bases. Chemical Reactions. Enzymes. More on Bioelements.

2. Macromolecules of Life.

Fundamentals. Carbohydrates. Lipids. DNA & RNA. Proteins. Genetic Code. Protein Structure and Function.

3. Cells and Their Housekeeping Functions.

Prokaryotes and Eukaryotes. Nuceleus. Organelles for Protein Synthesis and Transport. Cytoskeleton. Metabolic Processes and Mitochondria. Molecular Motors. Cell Membrane. Active Membrane Transport.

4. Gene Circuits.

Gene to Protein. Gene Anatomy. Gene Circuits. Bionetworks.

5. Genomics.

History of the Genome. Sequence Similarity and Homologous Genes. Decoding the Human Genome. Cutting and Sizing DNA. Making Multiple Copies. Sequencing. Gene Annotation. Plants and Animals with Modified Genomes.

6. Cell Adhesion and Communication.

Modes of Cell Communication. Extracellular Matrix and Integrins. Cell-cell Adhesions and Cadherine. Examples from Signal Transduction Pathways. Crosstalk between Signal Transduction Pathways.

7. Cell Division and its Regulation.

Modes of Cell Division. Molecular Basis of Cell Division. Cell Cycle Check Points. Phases of the Cell Cycle. Cell Culture.

8. Development of Multicellular Organisms.

From Unfertilized Egg to Zygote. Cleavage: First Stage of Development. Gastrulation. Pattern-Generating Genes. Stem Cells and Tissue Engineering.

9. Large Scale Biology.

Microarrays. Proteomics. Protein Structure. System Biology.

Glossary.

商品描述(中文翻譯)

 

適用於工程與計算機科學系的生物學課程。


本書採取系統方法來揭示現代生物學，介紹所有生物物種共同的基本系統原則和參數。這本書的簡明檢視從分子細胞生物學的介紹開始，逐步深入到基因與蛋白質之間在代謝過程、信號傳遞、細胞分裂和胚胎發育中所觀察到的複雜相互關係。文本的獨特方法提供了人類基因組計畫的描述，回顧高通量生物學和生物信息學工具，並介紹基因電路和通路分析在細胞分裂、胚胎發育和代謝通路中的應用，以及新興的蛋白質組學科學。


目錄：


1. 生命的化學。



原子、分子與共價鍵。離子化合物與靜電鍵。水與氫鍵。脂質與范德瓦耳斯吸引力。酸與鹼。化學反應。酶。更多生物元素的內容。

2. 生命的大分子。


基本原理。碳水化合物。脂質。DNA與RNA。蛋白質。遺傳密碼。蛋白質的結構與功能。

3. 細胞及其維持功能。


原核生物與真核生物。細胞核。蛋白質合成與運輸的細胞器。細胞骨架。代謝過程與線粒體。分子馬達。細胞膜。主動膜運輸。

4. 基因電路。


基因到蛋白質。基因解剖。基因電路。生物網絡。

5. 基因組學。


基因組的歷史。序列相似性與同源基因。解碼人類基因組。切割與調整DNA。製作多重拷貝。測序。基因註釋。具有改造基因組的植物與動物。

6. 細胞黏附與通訊。


細胞通訊的模式。細胞外基質與整合素。細胞-細胞黏附與鈣黏蛋白。來自信號傳遞通路的例子。信號傳遞通路之間的交叉通訊。

7. 細胞分裂及其調控。


細胞分裂的模式。細胞分裂的分子基礎。細胞週期檢查點。細胞週期的階段。細胞培養。

8. 多細胞生物的發展。


從未受精卵到合子。卵裂：發展的第一階段。原腸形成。模式生成基因。幹細胞與組織工程。

9. 大規模生物學。


微陣列。蛋白質組學。蛋白質結構。系統生物學。

術語表。

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