Physical Principles in Sensing and Signaling: With an Introduction to Modeling in Biology
暫譯: 感測與信號中的物理原理:生物建模入門

Endres, Robert G.

  • 出版商: Oxford University
  • 出版日期: 2013-03-21
  • 售價: $1,890
  • 貴賓價: 9.5$1,796
  • 語言: 英文
  • 頁數: 184
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 0199600643
  • ISBN-13: 9780199600649
  • 相關分類: 理工類
  • 無法訂購

相關主題

商品描述

Although invisible to the bare eye, bacterial cells are large enough to make complex decisions. Cells are composed of thousands of different molecular species including DNA, proteins, and smaller molecules, allowing them to sense their environment, to process this information, and to respond accordingly. Such responses include expression of genes or the control of their movement. Despite these properties, a living cell exists in the physical world and follows its laws. Keeping this in mind can help answer questions such as how cells work and why they implement solutions to problems the way they do. Applying physical principles in biology allows researchers to solve challenging problems at the interface between biology and the physical sciences, including how accurately biological cells can sense chemicals in their environment, how cells encode physical stimuli in biochemical pathways, or how cells amplify signals and adapt to persistent stimulation. In this book, the reader is
introduced to this fascinating topic without the need for extensive mathematical details or huge prior knowledge in biological physics.

商品描述(中文翻譯)

雖然肉眼無法看見,細菌細胞卻足夠大,可以做出複雜的決策。細胞由成千上萬種不同的分子組成,包括DNA、蛋白質和較小的分子,使它們能夠感知環境、處理這些信息並作出相應的反應。這些反應包括基因表達或運動控制。儘管具備這些特性,活細胞仍然存在於物理世界中,並遵循其法則。記住這一點有助於回答細胞如何運作以及為何以特定方式解決問題等問題。在生物學中應用物理原則使研究人員能夠解決生物學與物理科學交界處的挑戰性問題,包括生物細胞如何準確感知環境中的化學物質、細胞如何在生化途徑中編碼物理刺激,或細胞如何放大信號並適應持續的刺激。在本書中,讀者將接觸到這一迷人的主題,而無需深入的數學細節或大量的生物物理學先前知識。

作者簡介


At Imperial College Robert Endres heads the Biological Physics Group. Recently he won the prestigious ERC Strating Grant award. Before moving to the United Kingdom, Robert was a postdoc with Prof. Ned Wingreen in the Molecular Biology Department at Princeton University, where his main research accomplishments were the understanding of the remarkable signalling properties of bacterial chemotaxis and the atomistic prediction of protein-DNA binding sites.

作者簡介(中文翻譯)

在帝國學院,羅伯特·恩德雷斯(Robert Endres)負責生物物理小組。最近,他獲得了享有盛譽的歐洲研究委員會(ERC)起始獎(Strating Grant)。在移居英國之前,羅伯特曾在普林斯頓大學的分子生物學系擔任奈德·溫格林(Ned Wingreen)教授的博士後研究員,他的主要研究成就包括理解細菌趨化的卓越信號特性以及原子層級預測蛋白質-DNA結合位點。