Molecular and Cellular Mechanisms of Toxicity

First Published in 1995: Written by specialists in their fields, this book contains short reviews intended to highlight points of growing interest in mechanistic toxicology. The first section considers selected aspects of molecular mechanisms, including selectivity of toxic agents and repair processes in the nervous system, toxicity of oxygen, fibers and aflatoxins. The second section discusses the interactions of carcinogens with DNA, and other targets, and their relevance to both molecular dosimetry of exposure and development of cancer. The final part is concerned with cellular and genetic aspects and includes coverage of some of the most recent and rapidly developing problems in toxicology.

Francesco De Matteis is a Professor at the Institute of Pharmacology, University of Turin, Italy.

Lewis L. Smith is a Professor at the MRC Toxicology Unit, University of Leicester, England.