Environmental Toxicology: Xenobiotics and Effects on Human Genetic Material
暫譯: 環境毒理學：外來物質及其對人類遺傳物質的影響
Priya, Kanu, Giri, Shiv Kumar
商品描述
This contributed volume is a comprehensive resource on the eventual fate of xenobiotics in the environment and their impact on the human genetic material in one integrated approach. The book offers a multi-disciplinary expertise of authors who are specialized in environmental science, toxicology, genetics, and epidemiology for a thorough understanding of complex interactions of xenobiotics with the environment and human health. The book offers both theory chapters and case studies, including studies on how omics technologies like genomics, transcriptomics, and epigenomics may be applied in order to assess the effect of xenobiotics on human genetic material.
Environmental toxicology is a multidisciplinary field that investigates adverse effects of xenobiotics, such as pollutants and toxic substances, on living organisms and the environment. The fate of xenobiotics in the environment is characterized by their release, transport, transformation, and degradation, which can cause bioaccumulation and biomagnification in food chains. The impact of exposure to xenobiotics has been documented to be catastrophic for human health, ranging from genetic damage to mutations and epigenetic changes. Exposure to pesticides, heavy metals, and industrial chemicals has been identified to increase the risk of cancer, reproductive problems, and neurodevelopmental disorders. Such influences of xenobiotics on human genetic material are the reason for much concern, because this can lead to heritable changes and affect not only the person but also his future generations. Epigenetic modification, such as DNA methylation and histone modification, can also influence the expression of genes and raise susceptibility to diseases.
商品描述(中文翻譯)
這本貢獻集是關於外來物質在環境中的最終命運及其對人類遺傳物質影響的綜合資源。該書提供了多學科的專家知識，作者專精於環境科學、毒理學、遺傳學和流行病學，以便深入理解外來物質與環境及人類健康之間的複雜互動。書中包含理論章節和案例研究，包括如何應用基因組學（genomics）、轉錄組學（transcriptomics）和表觀基因組學（epigenomics）等組學技術來評估外來物質對人類遺傳物質的影響。
環境毒理學是一個多學科領域，研究外來物質（如污染物和有毒物質）對生物體和環境的負面影響。外來物質在環境中的命運特徵包括其釋放、運輸、轉化和降解，這可能導致食物鏈中的生物累積和生物放大。接觸外來物質對人類健康的影響已被記錄為災難性的，範圍從遺傳損傷到突變和表觀遺傳變化。接觸農藥、重金屬和工業化學品已被確定會增加癌症、生殖問題和神經發展障礙的風險。外來物質對人類遺傳物質的這些影響引起了極大的關注，因為這可能導致可遺傳的變化，影響不僅是個體，還有其未來的後代。表觀遺傳修飾，如DNA甲基化和組蛋白修飾，也可以影響基因的表達並提高對疾病的易感性。
作者簡介
Dr. Kanu Priya, is working as an Associate Professor in the Department of Life Science in the School of Bioscience and Technology at Sharda University, Greater Noida, India. Her specialization is in animal biotechnology, nanobiotechnology, environmental biotechnology, and pharmacology and toxicology. She has been teaching graduate and postgraduate students of biotechnology with total experience of more than 9 years. She had served as head of the department in her previous institution. She has taught topics related to animal biotechnology, microbiology, genetic engineering, and IPR. She has authored more than 35 scientific articles and 6 book chapters from international publishers. She has 14 patents published (4 granted). She has received 40 lakhs project from Ministry of Ayush. She has also completed 2 small granted projects. She received a best women research award for excellence in research in 2025 by Springer Nature under "Her research, our future". She has presented her work on national and international platforms in conferences and workshops. She has served as an editorial board member and reviewer for several reputed international journals.
Dr. Shiv Kumar Giri is a renowned academic and researcher, currently serving as the Head of Department and Professor in the Department of Biotechnology at Maharaja Agrasen University, Baddi, Himachal Pradesh. With over 15 years of research expertise and a decade of teaching experience, Dr. Giri's areas of specialization include environmental toxicology, genomics, bioinformatics, and stem cell technology. Dr. Giri has successfully guided four PhD scholars and completed a prestigious research project on stem cell funded by the DST-SERB, Government of India, in 2016, showcasing his ability to lead impactful research initiatives. He has also made significant contributions to scientific literature through numerous research papers, book chapters, and as an editor of three books within his field. Prior to his current role, Dr. Giri served as an Assistant Professor in the Department of Biotechnology at University College, Kurukshetra University. His career reflects a strong commitment to advancing biotechnology education and research innovation.
作者簡介(中文翻譯)
Dr. Kanu Priya 現任印度大諾伊達沙達大學生命科學系副教授。她的專業領域包括動物生物技術、奈米生物技術、環境生物技術以及藥理學和毒理學。她擁有超過9年的生物技術研究生和碩士生教學經驗，曾在前任機構擔任系主任。她教授的課題包括動物生物技術、微生物學、基因工程和智慧財產權（IPR）。她已發表超過35篇科學文章和6章國際出版社的書籍章節，並擁有14項已發表的專利（其中4項已獲得批准）。她獲得了來自Ayush部的400萬印度盧比的項目資助，並完成了2個小型資助項目。她於2025年獲得Springer Nature頒發的最佳女性研究獎，以表彰其在研究方面的卓越表現，主題為「她的研究，我們的未來」。她在國內外的會議和研討會上展示了她的研究成果，並擔任多本國際知名期刊的編輯委員會成員和審稿人。
Dr. Shiv Kumar Giri 是一位著名的學者和研究人員，目前擔任印度喜馬偕爾邦巴迪的Maharaja Agrasen University生物技術系系主任及教授。擁有超過15年的研究專業知識和10年的教學經驗，Giri博士的專業領域包括環境毒理學、基因組學、生物資訊學和幹細胞技術。Giri博士成功指導了四位博士生，並於2016年完成了一項由印度政府DST-SERB資助的幹細胞研究項目，展現了他在推動有影響力的研究計畫方面的能力。他還通過多篇研究論文、書籍章節以及擔任三本專業書籍的編輯，對科學文獻做出了重要貢獻。在擔任目前職位之前，Giri博士曾在庫魯克舍特拉大學的生物技術系擔任助理教授。他的職業生涯反映了他對推進生物技術教育和研究創新的堅定承諾。
