Cell Signaling, 2nd Edition: Principles and Mechanisms
暫譯: 細胞信號傳遞(第二版):原則與機制

Lim, Wendell A., Mayer, Bruce J.

  • 出版商: CRC
  • 出版日期: 2024-10-30
  • 售價: $3,660
  • 貴賓價: 9.5$3,477
  • 語言: 英文
  • 頁數: 441
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 0367279371
  • ISBN-13: 9780367279370
  • 相關分類: 生物資訊 Bioinformatics
  • 海外代購書籍(需單獨結帳)

相關主題

商品描述

Cell Signaling provides undergraduate and graduate students with the conceptual tools needed to make sense of the dizzying array of pathways that cells use to detect, process, and respond to signals from the environment. By emphasizing the common design principles and molecular processes that underlie all signaling mechanisms, the book develops a broad conceptual framework through which students can understand diverse signaling pathways and networks. The book first examines the common currencies of cellular information processing and the core components of the signaling machinery. It then shows how these individual components link together into networks and pathways to perform more sophisticated tasks. Many specific examples are provided throughout to illustrate common principles, and to provide a comprehensive overview of major signaling pathways.

Thoroughly revised, this second edition includes two new chapters and substantial updates to the text and figures throughout the book.

Key features:

  • The book provides a conceptual framework through which all signaling pathways can be understood without memorization of details
  • It is extensively illustrated, including high-quality diagrams and schematics to elucidate important concepts and processes
  • Each chapter concludes with a useful summary section that brings together the key concepts
  • End-of-chapter review questions test the reader's understanding of the material covered
  • Two new chapters have been written especially for this edition: "Signaling and Disease" and "Diversity in Signaling across Phylogeny"

商品描述(中文翻譯)

《細胞訊號傳遞》為本科生和研究生提供了理解細胞用來檢測、處理和回應環境信號的眾多途徑所需的概念工具。通過強調所有訊號機制背後的共同設計原則和分子過程,本書建立了一個廣泛的概念框架,使學生能夠理解多樣的訊號途徑和網絡。本書首先檢視細胞信息處理的共同貨幣和訊號機械的核心組件。接著展示這些個別組件如何連結成網絡和途徑,以執行更複雜的任務。全書提供了許多具體範例,以說明共同原則,並提供主要訊號途徑的全面概述。

這一版經過徹底修訂,包含兩個新章節,並對全書的文本和圖形進行了大量更新。

主要特點:
- 本書提供了一個概念框架,使所有訊號途徑能夠在不需記憶細節的情況下被理解
- 本書插圖豐富,包括高品質的圖表和示意圖,以闡明重要概念和過程
- 每章結尾都有一個有用的總結部分,整合關鍵概念
- 章末的回顧問題測試讀者對所涵蓋材料的理解
- 這一版特別撰寫了兩個新章節:'訊號與疾病'和'系統發育中的訊號多樣性'

作者簡介

Wendell A. Lim is Professor of Cellular and Molecular Pharmacology at the University of California, San Francisco. The principal focus of his research is the structure and mechanism of protein interaction domains and the logic by which these components are used to build complex cellular signaling systems.

Bruce J. Mayer is Professor of Genetics and Genome Sciences at the University of Connecticut, School of Medicine. Current work of his group focuses on characterizing and manipulating tyrosine kinase-mediated signal transduction pathways.

作者簡介(中文翻譯)

Wendell A. Lim 是加州大學舊金山分校細胞與分子藥理學的教授。他的研究主要集中在蛋白質相互作用區域的結構和機制,以及這些組件用來構建複雜細胞信號系統的邏輯。

Bruce J. Mayer 是康乃爾大學醫學院遺傳學與基因組科學的教授。他的研究小組目前專注於表徵和操控酪氨酸激酶介導的信號傳導途徑。