Molecular Targets and Therapeutic Design: Volume 153
暫譯: 分子靶點與治療設計:第153卷

Donev, Rossen

  • 出版商: Academic Press
  • 出版日期: 2026-07-20
  • 售價: $6,040
  • 貴賓價: 9.5$5,738
  • 語言: 英文
  • 頁數: 528
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 0443345236
  • ISBN-13: 9780443345234
  • 海外代購書籍(需單獨結帳)

商品描述

Molecular Targets and Therapeutic Design, Volume 152 provides a comprehensive overview of the current landscape and future directions in the identification and exploitation of molecular targets for the development of new therapeutics. This volume brings together leading experts to discuss the fundamental principles of target discovery, validation, and the strategies used to design molecules that modulate biological pathways in disease. Topics covered in this new release include Recent Strategies and Approaches for the Development of Molecularly Targeted Nanomedicine, Transcriptomic Profiling for Therapeutic Target Discovery in Neuropsychiatric Conditions, Transcriptomic Insights into Hormone-Driven Malignancies: Toward Targeted Therapeutic Strategies, and much more.

Additional chapters cover Targeting Kinases in Neurodegenerative Diseases and Cancer: Structural Insights and Therapeutic Strategies, Small molecular therapeutic targets for neurodegenerative diseases, Signaling cascades of Tau protein, Understanding molecular role of lipids for Alzheimer's disease, Clinical Challenges and Therapeutic Strategies in Chordoma, Molecular Characterization and Experimental Models of Chordoma, Disordered Proteins as Fuzzy Viral Drug Targets, amongst other timely topics.

商品描述(中文翻譯)

《分子靶點與治療設計,第152卷》提供了當前分子靶點識別與利用的全景概述,以及未來在新療法開發中的方向。本卷匯集了領先的專家,討論靶點發現、驗證的基本原則,以及用於設計能調節疾病生物途徑的分子的策略。本次新書涵蓋的主題包括:分子靶向納米醫學的最新策略與方法、神經精神疾病中治療靶點發現的轉錄組分析、激素驅動的惡性腫瘤的轉錄組見解:朝向靶向治療策略等。

其他章節則涵蓋了針對神經退行性疾病和癌症的激酶靶向:結構見解與治療策略、小分子治療靶點在神經退行性疾病中的應用、Tau蛋白的信號傳遞級聯、理解脂質在阿茲海默症中的分子角色、脊索瘤的臨床挑戰與治療策略、脊索瘤的分子特徵與實驗模型、無序蛋白作為模糊病毒藥物靶點等及其他及時的主題。