Apolipoprotein E in Health and Disease: Unravelling Its Intricate Roles
暫譯: 健康與疾病中的載脂蛋白E:揭示其複雜角色

Kumar, Dileep, Ganeshpurkar, Ankit, Ganeshpurkar, Aditya

  • 出版商: Academic Press
  • 出版日期: 2026-06-26
  • 售價: $6,080
  • 貴賓價: 9.5$5,776
  • 語言: 英文
  • 頁數: 326
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 0443405638
  • ISBN-13: 9780443405631
  • 海外代購書籍(需單獨結帳)

相關主題

商品描述

Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease.

In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.

商品描述(中文翻譯)

健康與疾病中的載脂蛋白E:揭開其複雜角色》深入探討了載脂蛋白E(ApoE)在各種健康狀況和疾病中的多面向功能。這本綜合性著作提供了對ApoE的深入探索,闡明其結構洞察、功能意義和遺傳變異性。每一章節都檢視了ApoE在不同疾病背景下的角色,包括心血管疾病、阿茲海默症、神經系統疾病、代謝症候群、肝臟健康、癌症和炎症性疾病。關鍵章節調查了ApoE對脂質代謝、動脈粥樣硬化和心臟健康的影響,同時探討了其在阿茲海默症中的遺傳易感性和機制意涵。

此外,本書還擴展了對ApoE在認知衰退和其他神經系統疾病、代謝健康、肝功能、癌症風險和免疫調節等更廣泛影響的探索。書中強調了ApoE的藥物基因組學,為精準醫療鋪平了道路,提供了ApoE基因型如何影響藥物反應和治療策略的見解。未來在利用ApoE進行疾病管理方面的前景和挑戰也被討論,並探討了其在傳染病、基因工程創新和靶向藥物傳遞系統中的角色。