Computational Intelligence and Pattern Analysis in Biology Informatics (Hardcover)

Ujjwal Maulik, Sanghamitra Bandyopadhyay, Jason T. Wang

  • 出版商: Wiley
  • 出版日期: 2010-11-30
  • 定價: $3,998
  • 售價: 9.5$3,798
  • 語言: 英文
  • 頁數: 372
  • 裝訂: Hardcover
  • ISBN: 047058159X
  • ISBN-13: 9780470581599
  • 立即出貨 (庫存=1)

買這商品的人也買了...

商品描述

An invaluable tool in Bioinformatics, this unique volume provides both theoretical and experimental results, and describes basic principles of computational intelligence and pattern analysis while deepening the reader's understanding of the ways in which these principles can be used for analyzing biological data in an efficient manner.

This book synthesizes current research in the integration of computational intelligence and pattern analysis techniques, either individually or in a hybridized manner. The purpose is to analyze biological data and enable extraction of more meaningful information and insight from it. Biological data for analysis include sequence data, secondary and tertiary structure data, and microarray data. These data types are complex and advanced methods are required, including the use of domain-specific knowledge for reducing search space, dealing with uncertainty, partial truth and imprecision, efficient linear and/or sub-linear scalability, incremental approaches to knowledge discovery, and increased level and intelligence of interactivity with human experts and decision makers

  • Chapters authored by leading researchers in CI in biology informatics.
  • Covers highly relevant topics: rational drug design; analysis of microRNAs and their involvement in human diseases.
  • Supplementary material included: program code and relevant data sets correspond to chapters.

商品描述(中文翻譯)

這本書是生物信息學中一個非常寶貴的工具,提供了理論和實驗結果,並描述了計算智能和模式分析的基本原理,同時加深讀者對這些原理如何以高效的方式用於分析生物數據的理解。

這本書綜合了目前在計算智能和模式分析技術的整合方面的研究,無論是單獨使用還是混合使用。其目的是分析生物數據,並從中提取更有意義的信息和洞察力。進行分析的生物數據包括序列數據、二級和三級結構數據以及微陣列數據。這些數據類型很複雜,需要使用先進的方法,包括使用領域特定知識來減少搜索空間,處理不確定性、部分真實性和不確定性,實現高效的線性和/或次線性可擴展性,增量式的知識發現方法,以及與人類專家和決策者的互動水平和智能程度的提高。

本書的章節由生物信息學中的領先研究人員撰寫。涵蓋了非常相關的主題,包括合理的藥物設計、微小RNA的分析及其在人類疾病中的作用。附帶的資料包括程式碼和相應的數據集。