Protein Bioinformatics: An Algorithmic Approach to Sequence and Structure Analysis (Hardcover)

Genomics and bioinformatics play an increasingly important and transformative role in medicine, society and agriculture. The mapping of the human genome has revealed 35,000 or so genes which might code for more than one protein, resulting in 100,000 proteins for the humans alone. Since proteins are attractive targets for developing drugs, efforts are now underway to map sequences and assign functions to many novel proteins. This book takes the novel approach to cover both the sequence and structure analysis of proteins in one volume and from an algorithmic perspective.

Key features of the book include:

• Provides a comprehensive introduction to the analysis of protein sequence and structure analysis.
• Takes an algorithmic approach, relying on computational methods rather than theoretical.
• Provides an integrated presentation of theory, examples, exercises and applications.
• Includes coverage of both protein structure, and sequence, analysis.
• Accessible enough for biologists, yet rigorous enough for computer scientists and mathematicians.
• Supported by a Web site featuring exercises, solutions, images, and computer programs.

Visit this website for exercises with solutions, computer programs, errata and additional material:

http://www.ii.uib.no/proteinbioinformatics/

基因組學和生物信息學在醫學、社會和農業中扮演著越來越重要和轉型的角色。人類基因組的映射揭示了大約35,000個可能編碼超過一種蛋白質的基因，僅僅對於人類而言就可能產生100,000種蛋白質。由於蛋白質是開發藥物的有吸引力的目標，現在正在進行努力對許多新型蛋白質進行序列映射和功能分配。本書採用新穎的方法，從算法的角度涵蓋了蛋白質的序列和結構分析。

本書的主要特點包括：

• 提供了對蛋白質序列和結構分析的全面介紹。


• 採用算法方法，依賴於計算方法而不是理論方法。


• 提供了理論、示例、練習和應用的綜合呈現。


• 包括對蛋白質結構和序列分析的涵蓋。


• 對生物學家來說足夠易懂，對計算機科學家和數學家來說足夠嚴謹。


• 配有包含練習、解答、圖片和計算機程序的網站支持。

請訪問以下網站以獲取練習解答、計算機程序、勘誤和其他資料：

http://www.ii.uib.no/proteinbioinformatics/