RNA Synthetic Biology: Fundamentals and Applications
暫譯: RNA 合成生物學：基礎與應用

Singh, Vijai

RNA Synthetic Biology: Fundamentals and Applications
  • 出版商: CRC
  • 出版日期: 2026-03-31
  • 售價: $6,040
  • 貴賓價: 9.8 折 $5,919
  • 語言: 英文
  • 頁數: 282
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 1032660805
  • ISBN-13: 9781032660806
  • 相關分類: 生物資訊 Bioinformatics

    • 海外代購書籍(需單獨結帳)

商品描述

This reference book discusses the fundamental principles and applications of RNA synthetic biology. The initial section of the book provides on fundamental concepts including RNA synthetic biology, the use computational biology tools for RNA design, the SELEX (Systematic Evolution of Ligands by EXponential enrichment) method, artificial intelligence for design and prediction of RNA circuits, RNA structure prediction and folding algorithms, non-coding RNA, and in vitro selection of functional RNA. While this book also highlights the practical applications of RNA synthetic Biology. It offers design, construction and testing of riboswitches, riboregulators, RNA based biosensors, CRISPR for RNA detection, RNA editing, application in nanotechnology, RNA economics, ethics and regulatory issues. This book is intended for researchers and students of molecular biology, genetics, synthetic biology, and RNA biology.

Key feature

1) Presents fundamental principles and advanced applications of RNA Synthetic Biology

2) Reviews the applications of computational tools and artificial intelligence in the design, prediction, and analysis of RNAs and RNA circuits

3) Explores the role of RNA modifications on function and the regulatory roles of non-coding RNAs

4) Examines CRISPR-based RNA detection and RNA-based therapeutics for genetic diseases, cancer, and infectious diseases.

商品描述(中文翻譯)

這本參考書探討了RNA合成生物學的基本原則和應用。書的初始部分提供了基本概念，包括RNA合成生物學、使用計算生物學工具進行RNA設計、SELEX（系統性進化配體的指數富集）方法、人工智慧在RNA電路設計和預測中的應用、RNA結構預測和摺疊算法、非編碼RNA，以及體外篩選功能性RNA。這本書同時強調RNA合成生物學的實際應用，提供了設計、構建和測試核糖開關、核糖調節因子、基於RNA的生物感測器、用於RNA檢測的CRISPR、RNA編輯、在納米技術中的應用、RNA經濟學、倫理和監管問題。本書旨在為分子生物學、遺傳學、合成生物學和RNA生物學的研究人員和學生提供參考。

主要特點

1) 提出RNA合成生物學的基本原則和先進應用
2) 回顧計算工具和人工智慧在RNA及RNA電路的設計、預測和分析中的應用
3) 探討RNA修飾對功能的影響及非編碼RNA的調控角色
4) 檢視基於CRISPR的RNA檢測和針對遺傳疾病、癌症及傳染病的基於RNA的治療方法。

作者簡介

Dr. Vijai Singh is currently serving as Professor and Head of the Department of Biosciences, School of Science and Dean (Research & Innovation) at Indrashil University, Rajpur, Mehsana, India. Prior to this, he held the position of Associate Professor in the same department at Indrashil University. He has also served as Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, and in the Department of Biotechnology at the Invertis University, Bareilly, India. Earlier of his career, Dr Singh worked as a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and at the School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He earned his Ph.D. in Biotechnology in 2009 from the ICAR-National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. His doctoral research focused on the development of molecular and immunoassays for the diagnosis of Aeromonas hydrophila. Dr. Singh's research interests lies in the design and construction of novel biosynthetic pathways for production of medically and industrially important biomolecules. His laboratory is also actively engaged in developing CRISPR-Cas systems for gene knock out, knock in, gene regulation and diagnostic. With over 15 years of research and teaching experience, his areas of expertise include synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has an extensive academic record, with over 110 articles, 89 book chapters, 26 books and 3 patents to his credits. Dr. Singh has received number of prestigious awards, including the Bioclues Innovation, Research and Development Award (2023) from the BIOCLUES Society, the Vice Chancellor's Best Research Award (2023) from Indrashil University, and the Agathiyar Chemical Biology Award (2023) from the Society of Chemical and Synthetic Biology. At Indrashil University, he currently serves as chairman of the Board of Study, and is a member of the Academic Council of Indrashil University. He also holds the position of the Member Secretary of the Institutional Biosafety Committee (IBSC) at the university.

作者簡介(中文翻譯)

維賽·辛格博士目前擔任印度梅沙納拉吉普爾印德拉希爾大學生物科學系教授及系主任，以及研究與創新院長。在此之前，他曾在印德拉希爾大學的同一系別擔任副教授。他還曾在甘地納格爾的高級研究所生物科學與生物技術系，以及印度巴雷利的英維提斯大學生物技術系擔任助理教授。在職業生涯早期，辛格博士曾在法國巴黎的系統與合成生物學研究所的合成生物學小組及韓國蔚山科學技術院的能源與化學工程學院擔任博士後研究員。他於2009年在印度烏塔爾邦技術大學的ICAR-國家魚類遺傳資源局獲得生物技術博士學位。他的博士研究專注於開發用於診斷Aeromonas hydrophila的分子和免疫檢測。辛格博士的研究興趣在於設計和構建新穎的生物合成途徑，以生產醫療和工業上重要的生物分子。他的實驗室也積極從事開發CRISPR-Cas系統，用於基因敲除、敲入、基因調控和診斷。擁有超過15年的研究和教學經驗，他的專業領域包括合成生物學、代謝工程、生物資訊學、微生物學和工業微生物學。他擁有豐富的學術記錄，發表了超過110篇文章、89章書籍、26本書籍和3項專利。辛格博士獲得了多項著名獎項，包括2023年BIOCLUES協會的Bioclues創新、研究與發展獎、印德拉希爾大學的副校長最佳研究獎（2023年）以及化學與合成生物學協會的阿卡提亞化學生物學獎（2023年）。在印德拉希爾大學，他目前擔任學術委員會主席，並是印德拉希爾大學學術委員會的成員。他還擔任該大學機構生物安全委員會（IBSC）的成員秘書。

類似商品