Immuno-Model in Cancer: Methods and Protocols
暫譯: 癌症中的免疫模型:方法與實驗程序

Rani, Sweta, Skalniak, Lukasz

  • 出版商: Humana Press
  • 出版日期: 2025-10-02
  • 售價: $2,620
  • 貴賓價: 9.5$2,489
  • 語言: 英文
  • 頁數: 306
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 1071647334
  • ISBN-13: 9781071647332
  • 相關分類: 生物資訊 Bioinformatics
  • 無法訂購

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商品描述

This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA; immune checkpoint inhibitors; interactions of PD-1/PD-L1 and T cells; immunocompetent preclinical mouse models to study primary and metastatic brain cancer; and methods to generate CAR T-cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and comprehensive, Immuno-Model in Cancer: Methods and Protocols is a valuable resource for both new and experienced researchers who want to learn more about this important and developing field.

商品描述(中文翻譯)

這本開放存取的書籍描述了幫助研究人員理解癌症中免疫系統反應的計算和實驗模型,並測試實驗性的免疫腫瘤學方法。本書的章節涵蓋了多種方法,例如使用ELISA進行巨噬細胞的極化分析;免疫檢查點抑制劑;PD-1/PD-L1與T細胞的相互作用;用於研究原發性和轉移性腦癌的免疫功能前臨床小鼠模型;以及生成CAR T細胞的方法。本書採用成功的《Methods in Molecular Biology》系列格式撰寫,章節包括各自主題的介紹、所需材料和試劑的清單、逐步的可重複實驗室操作流程,以及故障排除和避免已知陷阱的提示。

前沿且全面的《Immuno-Model in Cancer: Methods and Protocols》是新手和經驗豐富的研究人員了解這一重要且不斷發展領域的寶貴資源。