Quantitative MRI of the Brain: Principles of Physical Measurement, Second edition (Series in Medical Physics and Biomedical Engineering)
暫譯: 腦部定量MRI：物理測量原理（醫學物理與生醫工程系列，第二版）

Quantitative MRI of the Brain: Principles of Physical Measurement, Second edition (Series in Medical Physics and Biomedical Engineering)
  • 出版商: CRC
  • 出版日期: 2018-01-26
  • 售價: $5,770
  • 貴賓價: 9.5 折 $5,482
  • 語言: 英文
  • 頁數: 360
  • 裝訂: Hardcover
  • ISBN: 1138032859
  • ISBN-13: 9781138032859
  • 相關分類: 物理學 Physics

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商品描述

Building on the success of the first edition of this book, the winner of the 2004 British Medical Association Radiology Medical Book Competition, Quantitative MRI of the Brain: Principles of Physical Measurement gives a unique view on how to use an MRI machine in a new way. Used as a scientific instrument it can make measurements of a myriad of physical and biological quantities in the human brain and body. For each small tissue voxel, non-invasive information monitors how tissue changes with disease and responds to treatment.

The book opens with a detailed exposition of the principles of good practice in quantification, including fundamental concepts, quality assurance, MR data collection and analysis and improved study statistical power through minimised instrumental variation. There follow chapters on 14 specific groups of quantities: proton density, T1, T2, T2*, diffusion, advanced diffusion, magnetisation transfer, CEST, 1H and multi-nuclear spectroscopy, DCE-MRI, quantitative fMRI, arterial spin-labelling and image analysis, and finally a chapter on the future of quantification. The physical principles behind each quantity are stated, followed by its biological significance. Practical techniques for measurement are given, along with pitfalls and examples of clinical applications.

This second edition of this indispensable 'how to' manual of quantitative MR shows the MRI physicist and research clinician how to implement these techniques on an MRI scanner to understand more about the biological processes in the patient and physiological changes in healthy controls. Although focussed on the brain, most techniques are applicable to characterising tissue in the whole body.

This book is essential reading for anyone who wants to use the gamut of modern quantitative MRI methods to measure the effects of disease, its progression, and its response to treatment.

商品描述(中文翻譯)

本書建立在第一版的成功基礎上，獲得2004年英國醫學協會放射學醫學書籍競賽的獎項，《腦部定量MRI：物理測量原則》提供了一種獨特的視角，展示如何以全新的方式使用MRI機器。作為一種科學儀器，它可以測量人腦和身體中無數的物理和生物量。對於每個小的組織體素，非侵入性的信息監測組織如何隨著疾病變化及對治療的反應。

本書開篇詳細闡述了定量的良好實踐原則，包括基本概念、質量保證、MR數據收集與分析，以及通過最小化儀器變異來提高研究的統計效能。接下來的章節涵蓋了14個特定量的組別：質子密度、T₁、T₂、T₂*、擴散、高級擴散、磁化轉移、CEST、¹H和多核光譜學、DCE-MRI、定量fMRI、動脈自旋標記和影像分析，最後一章探討了定量的未來。每個量的物理原理都被陳述，隨後是其生物學意義。提供了測量的實用技術，並附上陷阱和臨床應用的例子。

這本不可或缺的定量MR“如何做”手冊的第二版，向MRI物理學家和研究臨床醫生展示如何在MRI掃描儀上實施這些技術，以更好地理解患者的生物過程和健康對照組的生理變化。雖然重點在於腦部，但大多數技術也適用於全身組織的特徵描述。

本書是任何希望使用現代定量MRI方法來測量疾病影響、進展及其對治療反應的讀者必讀之作。

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