Introduction to BioMEMS (Hardcover)

Albert Folch

  • 出版商: CRC
  • 出版日期: 2012-08-21
  • 售價: $1,250
  • 貴賓價: 9.8$1,225
  • 語言: 英文
  • 頁數: 528
  • 裝訂: Hardcover
  • ISBN: 1439818398
  • ISBN-13: 9781439818398

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<內容簡介>

How Do We Make Small Things?

  • Why Bother Making Things Small?
  • From Art to Chips
  • Photolithography
  • Micromachining
  • Micromolding
  • Soft Lithography
  • Hydrogel Devices
  • Nanofabrication Techniques
  • Fabrication Based on Self-Assembly: A "Bottom-Up" Approach

Micropatterning of Substrates and Cells

  • Interaction between Surfaces and Biomolecules
  • Surface Engineering
  • Micropatterns of SAMs
  • Micropatterns of Proteins
  • Micropatterns of Cells on Nonbiomolecular Templates
  • Micropatterns of Cells on Biomolecular Templates

Microfluidics

  • Why Go Small?
  • Microscale Behavior of Fluids
  • Fluids in Electrical Fields
  • Fluids in Acoustic Fields
  • Fabrication of Microfluidic Channels
  • Operation of Microfluidic Channels: Practical Concerns
  • Droplet Microfluidics
  • Active Flow Control
  • Micromixers
  • Combinatorial Mixers

Molecular Biology on a Chip

  • The Importance of Miniaturizing Molecular Biology
  • The Importance of Point-of-Care Diagnostics: Where is Cost Really, Really, Really Important?
  • Sample Preparation: A Bloody Example
  • The Problem with Microfluidic Sample Separation
  • Microfluidic Immunoassays
  • Chips for Genomics and Proteomics
  • Electrospray Mass Spectrometry
  • Biochemical Analysis Using Force Sensors

Cell-Based Chips for Biotechnology

  • Microfluidic Flow Cytometers
  • Cell Sorting
  • Cell Trapping
  • Microfluidic Cell Culture Laboratories
  • Gene Expression Cellular Microarrays ("Cellomics")
  • Micro-Bioreactors
  • Cells on Microelectrodes
  • Patch Clamp Chips
  • Cryopreservation
  • Assisted Reproductive Technologies
  • Whole Animal Testing

BioMEMS for Cell Biology

  • An Enabling Technology: The Hurdles
  • Cell-Substrate Signaling
  • Cell-Cell Communication
  • Cell Migration
  • BioMEMS for Cellular Neurobiology
  • Developmental Biology on a Chip
  • Yeast Biology
  • Plant Cell Biology
  • Microfluidics for Studying Cellular Dynamics

Tissue Microengineering

  • Microscaffolding
  • Micropatterned Cocultures
  • Stem Cell Engineering
  • Morphogenesis

Implantable Microdevices

  • Dental Implants
  • Implantable Microelectrodes
  • Delivery of Soluble Signals into the Body
  • Microtools for Surgery
  • Insect Research

Appendix

Index