Autism Spectrum Disorder: Understanding the Female Phenotype
暫譯: 自閉症譜系障礙：理解女性表型

Mazzone, Luigi, Siracusano, Martina, Pelphrey, Kevin A.

Autism Spectrum Disorder: Understanding the Female Phenotype
  • 出版商: Springer
  • 出版日期: 2024-08-20
  • 售價: $4,770
  • 貴賓價: 9.5 折 $4,532
  • 語言: 英文
  • 頁數: 198
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 3031620712
  • ISBN-13: 9783031620713

    • 海外代購書籍(需單獨結帳)

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商品描述

This book provides a comprehensive overview of the current state of knowledge on autism in females, in order to help understand and clarify gender implications in the autistic female phenotype. Despite the reported higher risk of developing autism in males than in females, few studies have investigated the gender differences at the clinical and neurobiological level. Possible genetic protective factors, as well as differing neurobiological brain trajectories, could be responsible for the male/female discrepancy in prevalence rates (4:1). Moreover, a different clinical phenotype regarding the onset of symptoms, behavioral features and social motivation often skews diagnosis in women. Specifically, the phenomenon of camouflaging or hiding symptoms in high functioning females, due to behavioral coping strategies, contributes to incorrect or delayed diagnosis.

In addition to addressing an important gap in the literature, this book provides concrete and specific diagnostic recommendations and intervention strategies. In addition, a dedicated chapter presents clinical case reports and shares the personal experiences of autistic women. Given its scope, the book will appeal to clinicians and practitioners, as well as researchers and students in the fields of child and adult psychiatry, psychology and neuropsychiatry.

商品描述(中文翻譯)

本書提供了對女性自閉症現狀的全面概述，以幫助理解和澄清自閉症女性表型中的性別影響。儘管報告指出男性發展自閉症的風險高於女性，但很少有研究探討臨床和神經生物學層面的性別差異。可能的遺傳保護因素以及不同的神經生物學大腦發展軌跡，可能是造成男性/女性流行率差異（4:1）的原因。此外，關於症狀發作、行為特徵和社交動機的不同臨床表型，常常使女性的診斷出現偏差。具體而言，高功能女性因行為應對策略而掩飾或隱藏症狀的現象，導致不正確或延遲的診斷。

除了填補文獻中的重要空白，本書還提供具體和明確的診斷建議和干預策略。此外，專門的一章介紹臨床案例報告並分享自閉症女性的個人經歷。考慮到其範疇，本書將吸引臨床醫生和從業者，以及兒童和成人精神病學、心理學和神經精神病學領域的研究人員和學生。

作者簡介

Luigi Mazzone, MD, PhD, Full Professor in Child Neuropsychiatry. He is currently the Chief of the Child and Adolescent Psychiatry Division and the Director of the Medical Residency School of the University of Rome Tor Vergata, Italy. Several are the international fellowships he experienced during his academic career: the National Institute of Mental Health (NIMH), Bethesda, MD, USA; the Pediatric Brain Imaging Laboratory at Columbia University, NY, USA. Luigi Mazzone has focused his research and clinical activity both on the study of neurobiological substrates and on the characterization of the clinical phenotype of neurodevelopmental disorders such as autism spectrum disorder and ADHD. To date, he has published more than 150 articles in peer reviewed international scientific journals. He has already published with Springer the volume "Psychiatric Symptoms and Comorbidities in Autism Spectrum Disorder" in 2016.

Martina Siracusano, MD, PhD, is currently a Clinical Researcher at the Department of Biomedicine and Prevention of the University of Rome Tor Vergata (Italy) and carries out her main clinical activity in the Child and Adolescent Psychiatry Division of the Rome Tor Vergata University Hospital. Her primary research and clinical topic of interest is on autism spectrum disorder (early diagnosis, identification of biomarkers, medical comorbidities, genetic syndromes). She is actually involved in several research projects granted by the Italian National Health System focused on these themes.

Kevin Pelphrey, a neuroscientist and expert on child brain development, is the Harrison-Wood Professor of Neurology at the University of Virginia, USA. As a cognitive neuroscientist, his research investigates the brain basis of autism and related neurodevelopmental disorders. His multidisciplinary team seeks to understand the causes of autism to help get the right treatment to the right individual at the right time. Kevin is the Principal Investigator of the NIH Autism Center for Excellence--Neurogenetics of Females with Autism Network. His contributions to science have been recognized by receipt of a NIH Scientist Career Development Award, the John Merck Scholars Award, the Microsoft Corporation's Breakthrough Award, and the American Psychological Association's Boyd McCandless Award for distinguished early career theoretical contributions to Developmental Psychology. As a father and advocate, he serves by appointment of the United States Secretary of Health and Human Services as a member of the Federal Interagency Autism Coordinating Committee, USA.

作者簡介(中文翻譯)

路易吉·馬佐內，醫學博士，哲學博士，兒童神經精神病學全職教授。他目前是義大利羅馬托爾維爾加大學兒童與青少年精神病學部門的主任及醫學住院醫師學校的校長。在他的學術生涯中，他曾參加多個國際獎學金計畫：美國馬里蘭州貝塞斯達的國立精神衛生研究所（NIMH）；美國紐約哥倫比亞大學的兒童腦成像實驗室。路易吉·馬佐內的研究和臨床活動專注於神經生物學基礎的研究以及神經發展障礙的臨床表型特徵的描述，例如自閉症譜系障礙和注意力不足過動症（ADHD）。截至目前，他已在國際同行評審的科學期刊上發表超過150篇文章。他於2016年與Springer出版了《自閉症譜系障礙中的精神病症狀與共病情況》一書。

馬丁娜·西拉卡薩諾，醫學博士，哲學博士，目前是義大利羅馬托爾維爾加大學生物醫學與預防系的臨床研究員，並在羅馬托爾維爾加大學醫院的兒童與青少年精神病學部門進行主要的臨床活動。她的主要研究和臨床興趣主題是自閉症譜系障礙（早期診斷、生物標記的識別、醫療共病、遺傳綜合症）。她目前參與多個由義大利國家衛生系統資助的研究項目，專注於這些主題。

凱文·佩爾弗里，神經科學家及兒童大腦發展專家，現任美國維吉尼亞大學哈里森-伍德神經學教授。作為一名認知神經科學家，他的研究探討自閉症及相關神經發展障礙的腦基礎。他的多學科團隊旨在了解自閉症的成因，以便在正確的時間為正確的個體提供合適的治療。凱文是美國國立衛生研究院自閉症卓越中心——女性自閉症神經遺傳學網絡的首席研究員。他對科學的貢獻獲得了國立衛生研究院科學家職業發展獎、約翰·梅克獎學金、微軟公司的突破獎，以及美國心理學會的博伊德·麥肯德利斯獎，以表彰他在發展心理學領域的卓越早期理論貢獻。作為一名父親和倡導者，他被美國衛生與公共服務部部長任命為美國聯邦自閉症協調委員會的成員。

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