Leucine-Rich Repeat Kinase 2 (Lrrk2)

Rideout, Hardy J.

  • 出版商: Springer
  • 出版日期: 2018-08-07
  • 售價: $6,640
  • 貴賓價: 9.5$6,308
  • 語言: 英文
  • 頁數: 271
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3319842870
  • ISBN-13: 9783319842875
  • 海外代購書籍(需單獨結帳)

商品描述

This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.