Collagen Mimetic Peptides and Their Biophysical Characterization
暫譯: 膠原蛋白模擬肽及其生物物理特性表徵

Xiao, Jianxi

Collagen Mimetic Peptides and Their Biophysical Characterization
  • 出版商: Springer
  • 出版日期: 2024-08-06
  • 售價: $5,270
  • 貴賓價: 9.5 折 $5,007
  • 語言: 英文
  • 頁數: 226
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 9811019401
  • ISBN-13: 9789811019401
  • 相關分類: 生物資訊 Bioinformatics

    • 海外代購書籍(需單獨結帳)

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商品描述

This book embarks on an enlightening journey through the molecular landscape of collagen mimic peptides, shedding light on their significance and potential. In the intricate realm of biomolecules, collagen's preeminence as the most abundant protein in the human body, forming the foundational scaffolding of tissues and organs, renders it a subject of profound scientific interest. It explores diverse facets related to collagen mimic peptides, spanning aspects such as bioinformatic analysis, synthetic strategies, pathological collagen targeting, and the construction of homotrimeric, heterotrimeric and self-assembled peptide models. Furthermore, it provides an exhaustive investigation into biophysical techniques, encompassing Circular Dichroism (CD), X-ray crystallography, Nuclear Magnetic Resonance (NMR), Fluorescence, and Raman spectroscopy, thereby empowering researchers to unravel the structural intricacies of these peptides. The book unravels the profound implications of collagen mimic peptides across a spectrum of scientific domains, including protein science, biomaterials, bioanalysis, and beyond. Its accessibility and insights cater not only to seasoned researchers but also to undergraduate and graduate students eager to delve into the complexities of this fundamental protein.

商品描述(中文翻譯)

本書展開了一段啟發性的旅程，深入探討膠原蛋白模擬肽的分子景觀，揭示其重要性和潛力。在生物分子的複雜領域中，膠原蛋白作為人體中最豐富的蛋白質，構成組織和器官的基礎支架，使其成為深具科學興趣的主題。本書探討與膠原蛋白模擬肽相關的多樣面向，包括生物信息學分析、合成策略、病理膠原蛋白靶向以及同聚三聚體、異聚三聚體和自組裝肽模型的構建。此外，本書對生物物理技術進行了全面的調查，涵蓋圓二色性（Circular Dichroism, CD）、X射線晶體學、核磁共振（Nuclear Magnetic Resonance, NMR）、螢光和拉曼光譜學，從而使研究人員能夠揭示這些肽的結構複雜性。本書揭示了膠原蛋白模擬肽在蛋白質科學、生物材料、生物分析等多個科學領域的深遠影響。其可讀性和見解不僅適合資深研究人員，也適合渴望深入了解這一基本蛋白質複雜性的本科生和研究生。

作者簡介

Dr. Jianxi Xiao received his bachelor's degree from Wuhan University in 2003 and completed his Ph.D. at Rutgers University-New Brunswick, New Jersey, in 2009. He pursued postdoctoral research at Rutgers University and subsequently attained a full professorship at Lanzhou University's College of Chemistry and Chemical Engineering in 2012. Dr. Xiao holds the distinguished title of Cuiying Scholar at Lanzhou University and is honored with the prestigious "Feitian Scholar" professorship in Gansu Province. In addition, he serves as Director of Medical Collagen Engineering Research Center in Gansu Province and as Director of Joint Collagen Research Center at Lanzhou University. His research interests encompass the development and characterization of innovative collagen mimic peptides, collagen-targeting peptide probes, and collagen-based biomaterials. Dr. Xiao's extensive work has significantly advanced our comprehension of collagen's structure, function, and pathology, leading to the publication of over 70 academic papers in esteemed journals.

作者簡介(中文翻譯)

蕭建熙博士於2003年獲得武漢大學的學士學位，並於2009年在美國新澤西州的羅格斯大學（Rutgers University-New Brunswick）完成博士學位。他在羅格斯大學進行了博士後研究，並於2012年在蘭州大學化學與化工學院獲得正教授職位。蕭博士擁有蘭州大學的崔英學者（Cuiying Scholar）榮譽稱號，並獲得甘肅省的「飛天學者」（Feitian Scholar）教授榮譽。此外，他還擔任甘肅省醫療膠原蛋白工程研究中心主任及蘭州大學聯合膠原蛋白研究中心主任。他的研究興趣包括創新膠原蛋白模擬肽的開發與特徵分析、膠原蛋白靶向肽探針以及基於膠原蛋白的生物材料。蕭博士的廣泛研究顯著提升了我們對膠原蛋白結構、功能及病理的理解，並在知名期刊上發表了超過70篇學術論文。

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