商品描述
The book is a compilation of the latest developments in the technology and applications of stimuli-responsive nanosystems for cancer therapy. The book begins with an overview of recent advances in various stimuli, including endogenous triggers related to tumor microenvironments such as pH, temperature, enzymes and exogenous stimuli such as light, temperature, ultrasound and magnetic field, which could significantly augment anticancer therapy. A gamut of nanosystems investigated for cancer therapy, some major systems being liposomes, polymer nanoparticles, lipid nanoparticles, inorganic nanoparticles, hybrid nanoparticles and a range of other nanosystems which are stimuli responsive are covered in detail in the subsequent chapters. The chapters comprehensively cover the various nanosystems from development to evaluation to their application. This book is a valuable resource for scientists, professors, researchers, as well as medical and industry professionals working in the area of cancer and targeted drug delivery. It is also proposed as a textbook for master's students opting for a course in targeted drug delivery
商品描述(中文翻譯)
本書匯編了最新的刺激響應納米系統在癌症治療中的技術與應用發展。書籍首先概述了各種刺激的最新進展，包括與腫瘤微環境相關的內源性觸發因素，如 pH 值、溫度、酶，以及外源性刺激，如光、溫度、超聲波和磁場，這些因素可以顯著增強抗癌治療。隨後的章節詳細介紹了多種用於癌症治療的納米系統，其中一些主要系統包括脂質體、聚合物納米顆粒、脂質納米顆粒、無機納米顆粒、混合納米顆粒以及其他一系列刺激響應的納米系統。各章節全面涵蓋了這些納米系統的開發、評估及其應用。本書對於在癌症及靶向藥物傳遞領域工作的科學家、教授、研究人員以及醫療和行業專業人士來說，是一個寶貴的資源。此外，本書也建議作為選擇靶向藥物傳遞課程的碩士生的教科書。
作者簡介
Padma V. Devarajan is Advisor and Chair Professor at the SIES School of Pharmaceutical Sciences with over three decades of experience as an academician and researcher. She was formerly Dean and Professor in Pharmacy and Member-Board of Governors, at the Institute of Chemical Technology, Mumbai, India. Her research focuses on the design and development of innovative targeted nanomedicine for cancer and infectious diseases, non-invasive bio-enhanced delivery of peptides, proteins, nucleic acids and interventions for veterinary health care. Her research addresses critical aspects such as scale-up, commercialization and affordability to ensure societal outreach. She has published extensively in peer-reviewed journals and is a reviewer for many journals. She has several patents and authored books. She is a recipient of several national and international research and innovation awards, including the Women in Science award of the Controlled Release Society Inc., USA. Dr. Sathish Dyawanapelly is an Assistant Professor at the Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai, India. He has a Ph.D. in pharmaceutics from the Institute of Chemical Technology, Mumbai, and a master's degree in pharmacy from the National Institute of Pharmaceutical Education and Research, Raebareli. His research area focuses on the design and development of drug delivery systems (polymer, lipid, and metal nanoparticles), biomaterials, nanomedicines, and pharmaceutical formulation technology. He has authored or co-authored numerous book chapters and published over 35 publications in peer-reviewed international journals and 3 book chapters. He developed and transferred 3 different technologies to industries. He is an Editorial member for Scientific Reports (Nature), PLOS ONE, Frontiers in Drug Delivery, Discover Pharmaceutical Sciences (Springer), and Current Indian Science (Bentham Science) and serves as a reviewer of peer-reviewed international journals. He is a member of many international scientific societies and organizations. Vijayabhaskarreddy Junnuthula is a grant-funded researcher at the University of Helsinki, Finland. His research prominently revolves around the development of nanomedicine, spanning various domains within pharmaceutical sciences, most notably pharmaceutics, pharmacokinetics, and local drug delivery for diverse therapeutic applications. He has been supported by the Finnish Cultural Foundation and was a recipient of the Marie Curie Fellowship from the European Commission under the Horizon 2020 program. He was awarded the Solvay Chair Prize at the French Society of Nanomedicine conference in Bordeaux, France. He published several high-impact journals as an author. He is a peer reviewer for several pharmaceutical science journals, such as the International Journal of Pharmaceutics, Journal of Drug Delivery Science and Technology, BMC Pharmacology, Signal Transduction, and Targeted Therapy.
作者簡介(中文翻譯)
Padma V. Devarajan 是 SIES 藥學科學院的顧問及講座教授，擁有超過三十年的學術及研究經驗。她曾擔任印度孟買化學技術學院的藥學院院長及教授，以及董事會成員。她的研究專注於創新靶向納米醫學的設計與開發，針對癌症和傳染病，非侵入性生物增強的肽、蛋白質、核酸的傳遞，以及獸醫健康護理的介入。她的研究解決了關鍵的問題，如擴大生產、商業化及可負擔性，以確保社會的普及。她在同行評審的期刊上發表了大量文章，並擔任多本期刊的審稿人。她擁有多項專利並著有書籍。她獲得了多項國內外研究與創新獎項，包括美國控制釋放學會的女性科學獎。
Dr. Sathish Dyawanapelly 是印度孟買化學技術學院藥學科學與技術系的助理教授。他擁有孟買化學技術學院的藥劑學博士學位，以及來自 Raebareli 國立藥學教育與研究所的藥學碩士學位。他的研究領域專注於藥物傳遞系統（聚合物、脂質和金屬納米顆粒）、生物材料、納米醫學及藥物配方技術的設計與開發。他撰寫或共同撰寫了多篇書籍章節，並在同行評審的國際期刊上發表了超過 35 篇文章及 3 篇書籍章節。他將 3 種不同的技術開發並轉移至產業。他是《Scientific Reports》（Nature）、《PLOS ONE》、《Frontiers in Drug Delivery》、《Discover Pharmaceutical Sciences》（Springer）及《Current Indian Science》（Bentham Science）的編輯成員，並擔任多本同行評審國際期刊的審稿人。他是多個國際科學學會和組織的成員。
Vijayabhaskarreddy Junnuthula 是芬蘭赫爾辛基大學的資助研究員。他的研究主要圍繞納米醫學的開發，涵蓋藥學科學中的多個領域，特別是藥劑學、藥物動力學及針對各種治療應用的局部藥物傳遞。他獲得芬蘭文化基金會的支持，並曾獲得歐洲委員會在地平線 2020 計畫下的瑪麗居里獎學金。他在法國波爾多的法國納米醫學學會會議上獲得了索爾維講座獎。他作為作者在多本高影響力的期刊上發表了數篇文章。他是多本藥學科學期刊的同行評審，如《International Journal of Pharmaceutics》、《Journal of Drug Delivery Science and Technology》、《BMC Pharmacology》、《Signal Transduction》和《Targeted Therapy》。
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