The Concise Manual of Apheresis Therapy
暫譯: 簡明血漿分離療法手冊

Dr. Eisei NOIRI

Dr. Eisei Noiri is internationally recognized for his contributions to the field of acute kidney injury and his expertise in acute blood purification therapy and apheresis. From 2005 to 2015, he served as Associate Professor and Head of the Department of Hemodialysis and Apheresis at the University of Tokyo Hospital. During this period, he was actively engaged in clinical practice, research, and education, while also promoting the standardization of therapies to enhance the quality and precision of patient care. Through the National University Liaison Council, these initiatives were disseminated among national university hospitals, contributing to the advancement of high-level clinical practice in Japan.
In the area of apheresis therapy--often performed in critically ill patients--Dr. Noiri has advocated for accurate, evidence-based prescriptions, sometimes described as "precision apheresis." Such approaches have played an important role in improving patient outcomes. Many of the core techniques of apheresis originated in Japan, and Dr. Noiri has endeavored to present them in a clear and accessible manner for both domestic and international audiences.
The first English edition of this manual was well received in Japan and abroad, including Chinese-speaking regions. The favorable reception of that edition has enabled the publication of this revised second edition. It is the editor's sincere hope that this volume will serve as a useful reference for healthcare teams engaged in apheresis worldwide.

Prof. Kent DOI

Prof. Kent Doi is internationally recognized as a leading authority in acute kidney injury and critical care medicine. Originally trained as a nephrologist and now serving as a critical care physician, he has become one of Japan's most respected key opinion leaders, bridging two disciplines with a rare breadth of expertise.
At the University of Tokyo Hospital, he chairs the Department of Emergency and Critical Care Medicine, where his leadership extends across nephrology, emergency medicine, and disaster medical management. He also serves as President of the Japanese Society for Acute Blood Purification in Critical Care and Vice President of the Japanese Society for Emergency Medicine. In these roles, he plays a pivotal part in shaping the direction of Japan's acute medicine, ensuring that the nation's critical care system--from disaster response to pandemic preparedness--remains resilient and forward-looking.
Prof. Doi has been at the forefront of integrating big data analytics and artificial intelligence into acute care research, pioneering predictive models that redefine how we anticipate and respond to patient deterioration. His work has helped establish precision medicine approaches in AKI and blood purification, combining advanced science with bedside relevance.
With his broad vision and global standing, Prof. Doi brings both authority and innovation to this revised edition. His editorial guidance has ensured that the book reflects not only Japan's unique leadership in blood purification therapy, but also the evolving international standards of critical care.

野入英生博士

野入英生博士因其在急性腎損傷領域的貢獻以及在急性血液淨化療法和血漿分離術方面的專業知識而享有國際聲譽。從2005年到2015年，他擔任東京大學醫院血液透析與血漿分離科的副教授及科主任。在此期間，他積極參與臨床實踐、研究和教育，同時推動療法的標準化，以提高病人護理的質量和精確性。通過國立大學聯絡協會，這些倡議在全國大學醫院中得以傳播，促進了日本高水平臨床實踐的發展。

在血漿分離療法領域——通常在重症病人中進行——野入博士提倡準確、基於證據的處方，有時被稱為「精準血漿分離」。這些方法在改善病人結果方面發揮了重要作用。許多血漿分離的核心技術源於日本，野入博士努力以清晰且易於理解的方式向國內外觀眾介紹這些技術。

本手冊的第一版英文版在日本及海外，包括中文地區，均受到良好評價。該版的良好反響使得本修訂第二版的出版成為可能。編輯真誠希望本書能成為全球從事血漿分離的醫療團隊的有用參考。

土井健教授

土井健教授在急性腎損傷和重症醫學領域享有國際聲譽，並被認為是領先的權威。最初受訓為腎臟科醫生，現在擔任重症醫生，他已成為日本最受尊敬的關鍵意見領袖之一，將兩個學科的專業知識結合在一起，展現出罕見的廣度。

在東京大學醫院，他擔任急診與重症醫學科的主任，其領導範圍涵蓋腎臟科、急診醫學和災害醫療管理。他還擔任日本急性血液淨化重症醫學會的會長和日本急診醫學會的副會長。在這些角色中，他在塑造日本急性醫學的方向上發揮了關鍵作用，確保國家的重症醫療系統——從災害應對到疫情準備——保持韌性和前瞻性。

土井教授在將大數據分析和人工智慧整合進急性護理研究方面處於前沿，開創了重新定義我們如何預測和應對病人惡化的預測模型。他的工作幫助建立了急性腎損傷和血液淨化中的精準醫療方法，將先進科學與臨床相關性相結合。

憑藉其廣闊的視野和全球地位，土井教授為本修訂版帶來了權威性和創新性。他的編輯指導確保了本書不僅反映了日本在血液淨化療法中的獨特領導地位，還體現了不斷演變的國際重症醫療標準。