Pseudotyped Viruses

Wang, Youchun

  • 出版商: Springer
  • 出版日期: 2024-04-15
  • 售價: $7,480
  • 貴賓價: 9.5$7,106
  • 語言: 英文
  • 頁數: 348
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 9819901154
  • ISBN-13: 9789819901159
  • 海外代購書籍(需單獨結帳)

商品描述

This book intends to report the new progress of pseudotyped viruses, including the construction of pseudotyped viruses with different strategies or vectors for most important viruses. Especially for emerging viruses, optimization of the condition and parameters for assay development based on the pseudotyped viruses and widely application as surrogate of authentic virus to study the biological functions of virus, detection of neutralizing antibody, screening viral entry inhibiters, and others. It includes most pseudotyped viruses that have the protein of the target virus on the surface of the parent virus with incomplete genome. The book is likely to be of interest to all researchers in the field of virology, vaccine, and anti-viral drug development and evaluation.

商品描述(中文翻譯)

本書旨在報告偽型病毒的最新進展,包括使用不同策略或載體構建偽型病毒以應對最重要的病毒。尤其針對新興病毒,優化基於偽型病毒的測試開發條件和參數,並廣泛應用偽型病毒作為真實病毒的替代品,研究病毒的生物功能、檢測中和抗體、篩選病毒進入抑制劑等。本書包括大多數偽型病毒,其表面蛋白是不完整基因組的目標病毒的蛋白。本書對於病毒學、疫苗和抗病毒藥物的研究和評估領域的所有研究人員可能都感興趣。

作者簡介

Dr. Youchun Wang is now professor and executive director of Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Kunming, China. He used to be chief expert on quality control of vaccines and deputy director of the National Institutes for Food and Drug Controls (NIFDC), co-director of WHO Collaborating Center for Standardization and Evaluation of Biologicals, and director of NMPA Key Laboratory for Quality Research and Evaluation of Biological Products. He got his Medical Degree (MD) on Epidemiology from Peking Medical University and PhD on Virology from University College London (UCL). He has mainly done research works on hepatitis virus, HIV, HPV, and emerging viruses such as Ebola virus, SARS-CoV-2, and others. He now focuses on pseudotyped viruses for different viruses, especially for emerging viruses, and has also developed new methods for quality control of viral vaccines and diagnostics. He obtained several grants from WellcomeTrust in UK, Ministry of Science and Technology, National Foundation of Natural Science, and others in China. He has published more than 320 academic papers, 150 of which were published in Cell, Nature, Science, Cell Host & Microbe, and other SCI journals as the first or corresponding author. His book was also published by Springer Nature before. He has held several positions in academic associations, such as former Chairman of Medical Virology and Vice Chairman of Medical Microbiology and Immunology of Chinese Medical Association, former Vice Chairman of Chinese Laboratory Animal Association, former Chairman of Beijing Medical Virology, and Chairman of the vaccine committee of Chinese Pharmacopoeia.

作者簡介(中文翻譯)

王友春博士現任中國醫學科學院與北京協和醫學院醫學生物學研究所的教授和執行主任。他曾擔任國家食品藥品監督管理局疫苗質量控制首席專家和副局長,世界衛生組織生物製品標準化與評價合作中心聯合主任,以及國家藥品監督管理局生物製品質量研究與評價重點實驗室主任。他在北京醫科大學獲得流行病學醫學學位(MD),在倫敦大學學院(UCL)獲得病毒學博士學位(PhD)。他主要從事肝炎病毒、HIV、HPV以及埃博拉病毒、SARS-CoV-2等新興病毒的研究工作。他目前專注於不同病毒的偽型病毒研究,尤其是新興病毒,並且還開發了病毒疫苗和診斷的新方法。他獲得了英國威康信託基金、中國科技部、國家自然科學基金等多個資助。他發表了320多篇學術論文,其中150篇發表在Cell、Nature、Science、Cell Host & Microbe等SCI期刊上,作為第一作者或通訊作者。他的書也曾由Springer Nature出版。他在學術協會中擔任過多個職位,如中國醫學會醫學病毒學分會前主任、醫學微生物學和免疫學副主任委員,中國實驗動物學會前副主任委員,北京醫學病毒學會主任委員,以及中國藥典疫苗專業委員會主任。