Introduction to Cell Mechanics and Mechanobiology
暫譯: 細胞力學與機械生物學導論

Jacobs, Christopher R., Huang, Hayden, Mofrad, Mohammad R. Kaazempur

  • 出版商: CRC
  • 出版日期: 2026-09-23
  • 售價: $5,550
  • 貴賓價: 9.5 折 $5,272
  • 語言: 英文
  • 頁數: 312
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 0367477289
  • ISBN-13: 9780367477288
  • 相關分類: 靜力學 Engineering-mechanics
  • 海外代購書籍(需單獨結帳)

相關主題

商品描述

This comprehensive second edition provides a pedagogical introduction to cell mechanics and mechanobiology. featuring quantitative descriptions of key concepts and solved examples throughout. The textbook demonstrates how understanding cellular responses to mechanical forces allows us to predict cell behavior and functionality in various environments.

Introduction to Cell Mechanics and Mechanobiology, Second Edition, asks key questions about the quantitative concepts that comprise this interdisciplinary field. The authors provide clear explanations of complex mechanobiological phenomena, from single-molecule mechanics to whole-cell responses. This book covers essential topics, including cellular polymers, cytoskeleton networks, membrane mechanics, and mechanotransduction. There are primer chapters on solid mechanics, fluid mechanics, statistical mechanics, and cell biology to ensure accessibility for students from diverse backgrounds.

Designed for advanced undergraduate and graduate students in biomedical engineering, bioengineering, and mechanical engineering, users will appreciate complete derivations of relevant equations, practical laboratory applications, and comprehensive coverage of nuclear biomechanics. The twelve detailed chapters provide a complete framework for understanding the technical and biological aspects of cellular mechanics. Thus, this book is an invaluable resource for mastering the quantitative principles of mechanobiology.

商品描述(中文翻譯)

這本內容完整的第二版以教學導向介紹細胞力學與機械生物學(mechanobiology),全書貫穿關鍵概念的定量描述與詳盡的解題範例。本教材說明,了解細胞對機械力的反應,能讓我們預測細胞在各種環境中的行為與功能。

《Introduction to Cell Mechanics and Mechanobiology》第二版針對構成此一跨學科領域的定量概念,提出一系列關鍵問題。作者以清楚易懂的方式解釋複雜的機械生物學現象,涵蓋從單分子力學到整體細胞反應的各個層面。本書涵蓋細胞聚合物、細胞骨架網絡、膜力學與機械轉導(mechanotransduction)等重要主題。此外,書中也安排固體力學、流體力學、統計力學與細胞生物學的基礎章節,確保不同背景的學生都能理解內容。

本書專為生醫工程、生物工程與機械工程領域的高年級大學生及研究生設計。讀者將從中獲得相關方程式的完整推導、實際的實驗室應用,以及對細胞核生物力學的全面介紹。全書十二個詳盡章節,為理解細胞力學的技術與生物學層面提供完整架構。因此,本書是掌握機械生物學定量原理不可或缺的資源。

作者簡介

Christopher R. Jacobs (1965-2018) was a professor of Biomedical Engineering at Columbia University, where he served as the director of the Cell and Molecular Biomechanics Lab. A recognized leader in the field, Dr. Jacobs made seminal contributions to the understanding of bone cellular mechanotransduction and computational biomechanics, conducting research that aided in the development of new therapies for age-related bone loss and osteoporosis. His dedication to bridging the disciplines of mechanics and biology continues to influence the field.

Hayden Huang is a biomedical engineer by training. He currently works on issues at the intersection of health care and technology to help inform policymakers. Previously, he was a faculty member in the Department of Biomedical Engineering at Columbia University, where his research investigated cell mechanics and cardiovascular physiology. Dr. Huang was a key architect of the first edition of Introduction to Cell Mechanics and Mechanobiology, drawing on his experience teaching the subject to a wide range of students from engineering to biological backgrounds.

Mohammad R. Kaazempur Mofrad is a professor of Bioengineering and Mechanical Engineering at UC Berkeley, where he leads a multidisciplinary research program at the interface of biomechanics, mechanobiology, artificial intelligence (AI), and computational biology. His laboratory investigates how physical forces shape biological structure and function across molecular, cellular, and multicellular scales, while also developing computational tools and AI-driven approaches to advance human health.

作者簡介(中文翻譯)

Christopher R. Jacobs(1965–2018)曾任 Columbia University 生物醫學工程學教授,並擔任 Cell and Molecular Biomechanics Lab 主任。Jacobs 博士是該領域公認的先驅,對骨骼細胞機械轉導與計算生物力學的理解做出了奠基性貢獻;他的研究促進了針對老年性骨質流失與骨質疏鬆症的新療法開發。他致力於連結力學與生物學兩大學科,至今仍持續影響著這個領域。

Hayden Huang 受過生物醫學工程專業訓練。目前,他致力於研究醫療保健與科技交會領域的議題,協助政策制定者取得相關資訊。在此之前,他曾任 Columbia University 生物醫學工程學系教員,研究範疇涵蓋細胞力學與心血管生理學。Huang 博士是《Introduction to Cell Mechanics and Mechanobiology》第一版的主要策劃者之一;他將自身教授這門課程的經驗融入書中,這些經驗涵蓋從工程學到生物學等不同背景的廣泛學生。

Mohammad R. Kaazempur Mofrad 是 UC Berkeley 生物工程與機械工程學教授,並在生物力學、機械生物學、人工智慧(AI)與計算生物學的交界處,領導一項多學科研究計畫。他的實驗室探討物理力量如何在分子、細胞與多細胞等不同尺度上形塑生物結構與功能,同時也開發計算工具與 AI 驅動的方法,以推進人類健康領域的發展。